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anti-Human NRP2 Antibodies:
anti-Mouse (Murine) NRP2 Antibodies:
anti-Rat (Rattus) NRP2 Antibodies:
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Rat (Rattus) Monoclonal NRP2 Primary Antibody for IF, WB - ABIN968443
Chen, Chédotal, He, Goodman, Tessier-Lavigne: Neuropilin-2, a novel member of the neuropilin family, is a high affinity receptor for the semaphorins Sema E and Sema IV but not Sema III. in Neuron 1997
Show all 4 Pubmed References
Human Polyclonal NRP2 Primary Antibody for WB - ABIN655525
Davare, Lal, Peckham, Prajapati, Gultekin, Rubin, Keller: Secreted meningeal chemokines, but not VEGFA, modulate the migratory properties of medulloblastoma cells. in Biochemical and biophysical research communications 2014
Human Polyclonal NRP2 Primary Antibody for WB - ABIN442214
Roth, Agemy, Kotamraju, Braun, Teesalu, Sugahara, Hamzah, Ruoslahti: Transtumoral targeting enabled by a novel neuropilin-binding peptide. in Oncogene 2012
Human Polyclonal NRP2 Primary Antibody for IHC, IHC (p) - ABIN4338865
Fonseca, Bingle, Santos-Silva, Lopes, de Almeida, de Andrade, Mariano, Kowalski, Rangel, Martins, Meurer, Speight, Vargas: Semaphorins and neuropilins expression in salivary gland tumors. in Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2016
Human Monoclonal NRP2 Primary Antibody for CyTOF, FACS - ABIN4899777
Jaalouk, Ozawa, Sun, Lahdenranta, Schlingemann, Pasqualini, Arap: The original Pathologische Anatomie Leiden-Endothelium monoclonal antibody recognizes a vascular endothelial growth factor binding site within neuropilin-1. in Cancer research 2007
Cow (Bovine) Polyclonal NRP2 Primary Antibody for IHC, ELISA - ABIN1582215
Hey-Cunningham, Markham, Fraser, Berbic: Dysregulation of vascular endothelial growth factors and their neuropilin receptors in the eutopic endometrium of women with endometriosis. in Reproductive sciences (Thousand Oaks, Calif.) 2013
NRP2 (show NELL2 Antibodies) promotes tumourigenesis and metastasis in Oesophageal squamous cell carcinoma (ESCC) through deregulation of ERK-MAPK (show MAPK1 Antibodies)-ETV4 (show ETV4 Antibodies)-MMP-E-cadherin (show CDH1 Antibodies) signalling.
The summarizes the structure and function features of pathway-related molecules of VEGFC (show VEGFC Antibodies)/D-VEGFR3 (show FLT4 Antibodies)/NRP2 (show NELL2 Antibodies) axis, stages of various tumors and their molecular mechanisms and significances in tuthe expression changes of these molecules in different anatomic organs or histopathologic types or development lymphatic metastasis.
NRP2 (show NELL2 Antibodies) inhibits WDFY1 (show WDFY1 Antibodies) transcription by preventing the nuclear localization of a transcription factor, Fetal ALZ50-reactive clone 1 (FAC1 (show BPTF Antibodies)).
Sequence Requirements for Neuropilin-2 Recognition by ST8SiaIV (show ST8SIA4 Antibodies) and Polysialylation of Its O-Glycans.
the concurrent high expression of VEGF-C (show VEGFC Antibodies) and NRP2 (show NELL2 Antibodies) is predictive of the unfavorable prognosis in glioblastoma.
SEMA3F (show SEMA3F Antibodies)-NRP2 (show NELL2 Antibodies) interactions inhibit intracellular PI-3K activity, mTORC2 (show CRTC2 Antibodies)-dependent signaling, RhoA (show RHOA Antibodies) activity and cytoskeletal stress fiber formation.
NRP2 (show NELL2 Antibodies)/WDFY1 (show WDFY1 Antibodies) axis is required for maintaining endocytic activity in cancer cells, which supports their oncogenic activities and confers drug resistance.
Data show significant increases in semaphorin3C, 3D and their receptor neuropilin-2 in degenerate samples which were shown to contain nerves and blood vessels, compared to non-degenerate samples without nerves and blood vessels.
the novel interplay between PAX8 (show PAX8 Antibodies) and Neuropilin-2
This is the first study in the literature showing that neuropilin-2 and ezrin (show EZR Antibodies) are related with prognosis in patients with advanced renal cell carcinoma (show MOK Antibodies).
Nrp2 deficiency increased blood vessel permeability and decreased lymphatic vessel drainage during inflammation, highlighting the importance of the NRP2/SEMA3F (show SEMA3F Antibodies) pathway in the modulation of tissue swelling and resolution of postinflammatory edema.
These results point to a new role for NRP2 in the positioning of neurons during adult hippocampal neurogenesis, acting via the GSK3beta (show GSK3b Antibodies) signaling pathway.
The authors demonstrate that expression of Semaphorin-3F (show SEMA3F Antibodies) in the outer hair cell region inhibits type I spiral ganglion neuron process extension by activating Neuropilin-2 receptors expressed on spiral ganglion neurons.
neuropilin-2 is developmentally regulated.
Data show that Chicken ovalbumin upstream promoter transcription factor (show NR2F1 Antibodies) II (COUP-TFII (show NR2F2 Antibodies))-induced expression of Neuropilin-2 (Nrp2) and its down-regulation control the destination of preoptic area (POa)-derived GABAergic neurons.
Study demonstrates that polysialic acid-SynCAM 1 (show CADM1 Antibodies) defines a subpopulation of NG2 (show Vcan Antibodies) cells and identifies the presence of polysialic acid-NRP2 in microglia
This study suggested that neuropilins play an essential role in coordinating NCC (show SLC12A3 Antibodies) migration with fate specification.
High NRP2 expression is associated with medulloblastoma.
Npn2 is selectively expressed in distinct populations of commissural neurons in both the dorsal and ventral spinal cord.
Nrp2 contributes to the establishment of uncrossed projections by dopaminergic axons.
This gene encodes a member of the neuropilin family of receptor proteins. The encoded transmembrane protein binds to SEMA3C protein sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C and SEMA3F protein sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F, and interacts with vascular endothelial growth factor (VEGF). This protein may play a role in cardiovascular development, axon guidance, and tumorigenesis. Multiple transcript variants encoding distinct isoforms have been identified for this gene.
, receptor for VEGF165 and semaphorins class3
, vascular endothelial cell growth factor 165 receptor 2