Browse our NRP2 Proteins (NRP2)

Full name:
Neuropilin 2 Proteins (NRP2)
On are 12 Neuropilin 2 (NRP2) Proteins from 5 different suppliers available. Additionally we are shipping NRP2 Antibodies (106) and NRP2 Kits (20) and many more products for this protein. A total of 148 NRP2 products are currently listed.
1110048P06Rik, neuropilin-2, Np-2, Np2, Npn-2, Npn2, PRO2714, VEGF165R2
list all proteins Gene Name GeneID UniProt
NRP2 8828 O60462
NRP2 18187 O35375
NRP2 81527 O35276

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NRP2 Proteins (NRP2) by Origin

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Top referenced NRP2 Proteins

  1. Human NRP2 Protein expressed in Human Cells - ABIN2003250 : Chen, Chédotal, He, Goodman, Tessier-Lavigne: Neuropilin-2, a novel member of the neuropilin family, is a high affinity receptor for the semaphorins Sema E and Sema IV but not Sema III. in Neuron 1997 (PubMed)
    Show all 6 references for 2003250

  2. Human NRP2 Protein expressed in Human Cells - ABIN2003248 : Yuan, Moyon, Pardanaud, Bréant, Karkkainen, Alitalo, Eichmann: Abnormal lymphatic vessel development in neuropilin 2 mutant mice. in Development (Cambridge, England) 2002 (PubMed)
    Show all 6 references for 2003248

More Proteins for NRP2 Interaction Partners

Human Neuropilin 2 (NRP2) interaction partners

  1. NRP2 (show NELL2 Proteins) promotes tumourigenesis and metastasis in Oesophageal squamous cell carcinoma (ESCC) through deregulation of ERK-MAPK (show MAPK1 Proteins)-ETV4 (show ETV4 Proteins)-MMP-E-cadherin (show CDH1 Proteins) signalling.

  2. The summarizes the structure and function features of pathway-related molecules of VEGFC (show VEGFC Proteins)/D-VEGFR3 (show FLT4 Proteins)/NRP2 (show NELL2 Proteins) axis, stages of various tumors and their molecular mechanisms and significances in tuthe expression changes of these molecules in different anatomic organs or histopathologic types or development lymphatic metastasis.

  3. NRP2 inhibits WDFY1 transcription by preventing the nuclear localization of a transcription factor, Fetal ALZ50-reactive clone 1 (FAC1).

  4. Sequence Requirements for Neuropilin-2 Recognition by ST8SiaIV (show ST8SIA4 Proteins) and Polysialylation of Its O-Glycans.

  5. the concurrent high expression of VEGF-C (show VEGFC Proteins) and NRP2 (show NELL2 Proteins) is predictive of the unfavorable prognosis in glioblastoma.

  6. SEMA3F (show SEMA3F Proteins)-NRP2 (show NELL2 Proteins) interactions inhibit intracellular PI-3K activity, mTORC2 (show CRTC2 Proteins)-dependent signaling, RhoA (show RHOA Proteins) activity and cytoskeletal stress fiber formation.

  7. NRP2 (show NELL2 Proteins)/WDFY1 (show WDFY1 Proteins) axis is required for maintaining endocytic activity in cancer cells, which supports their oncogenic activities and confers drug resistance.

  8. Data show significant increases in semaphorin3C, 3D and their receptor neuropilin-2 in degenerate samples which were shown to contain nerves and blood vessels, compared to non-degenerate samples without nerves and blood vessels.

  9. the novel interplay between PAX8 (show PAX8 Proteins) and Neuropilin-2

  10. This is the first study in the literature showing that neuropilin-2 and ezrin (show EZR Proteins) are related with prognosis in patients with advanced renal cell carcinoma (show MOK Proteins).

Mouse (Murine) Neuropilin 2 (NRP2) interaction partners

  1. Nrp2 deficiency increased blood vessel permeability and decreased lymphatic vessel drainage during inflammation, highlighting the importance of the NRP2/SEMA3F (show SEMA3F Proteins) pathway in the modulation of tissue swelling and resolution of postinflammatory edema.

  2. These results point to a new role for NRP2 in the positioning of neurons during adult hippocampal neurogenesis, acting via the GSK3beta signaling pathway.

  3. The authors demonstrate that expression of Semaphorin-3F (show SEMA3F Proteins) in the outer hair cell region inhibits type I spiral ganglion neuron process extension by activating Neuropilin-2 receptors expressed on spiral ganglion neurons.

  4. neuropilin-2 is developmentally regulated.

  5. Data show that Chicken ovalbumin upstream promoter transcription factor (show NR2F1 Proteins) II (COUP-TFII (show NR2F2 Proteins))-induced expression of Neuropilin-2 (Nrp2) and its down-regulation control the destination of preoptic area (POa)-derived GABAergic neurons.

  6. Study demonstrates that polysialic acid-SynCAM 1 (show CADM1 Proteins) defines a subpopulation of NG2 (show Vcan Proteins) cells and identifies the presence of polysialic acid-NRP2 in microglia

  7. This study suggested that neuropilins play an essential role in coordinating NCC (show SLC12A3 Proteins) migration with fate specification.

  8. High NRP2 expression is associated with medulloblastoma.

  9. Npn2 is selectively expressed in distinct populations of commissural neurons in both the dorsal and ventral spinal cord.

  10. Nrp2 contributes to the establishment of uncrossed projections by dopaminergic axons.

NRP2 Protein Profile

Protein Summary

This gene encodes a member of the neuropilin family of receptor proteins. The encoded transmembrane protein binds to SEMA3C protein sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C and SEMA3F protein sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F, and interacts with vascular endothelial growth factor (VEGF). This protein may play a role in cardiovascular development, axon guidance, and tumorigenesis. Multiple transcript variants encoding distinct isoforms have been identified for this gene.

Alternative names and synonyms associated with NRP2

  • neuropilin 2 (NRP2)
  • neuropilin 2 (Nrp2)
  • 1110048P06Rik protein
  • neuropilin-2 protein
  • Np-2 protein
  • Np2 protein
  • Npn-2 protein
  • Npn2 protein
  • PRO2714 protein
  • VEGF165R2 protein

Protein level used designations for Neuropilin 2 Proteins (NRP2)

neuropilin-2 , neuropilin-2a(17) , neuropilin-2a(22) , neuropilin-2b(0) , receptor for VEGF165 and semaphorins class3 , vascular endothelial cell growth factor 165 receptor 2

8828 Homo sapiens
18187 Mus musculus
81527 Rattus norvegicus
374157 Gallus gallus
541004 Bos taurus
488487 Canis lupus familiaris
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