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Browse our anti-Dystrophin (DMD) Antibodies

Full name:
anti-Dystrophin Antibodies (DMD)
On www.antibodies-online.com are 101 Dystrophin (DMD) Antibodies from 21 different suppliers available. Additionally we are shipping Dystrophin Kits (42) and Dystrophin Proteins (7) and many more products for this protein. A total of 155 Dystrophin products are currently listed.
Synonyms:
BMD, cb664, CG7240, CG7243, CG7344, CG17750, CG31175, CG34157, CMD3B, det, DKFZp459C1629, DKFZp468A1620, DLP, DLP1, DLP2, DLP3, DLP186, dmd, dmDLP, dmDp186, dmDys, Dmel\\CG34157, DNADMD1, Dp71, Dp117, Dp186, Dp205, Dp427, DXS142, DXS164, DXS206, DXS230, DXS239, DXS268, DXS269, DXS270, DXS272, DXSmh7, DXSmh9, dys, GI3046716, IDLP, im:6911785, mdx, MGC79631, MGC83347, pke, RATDMD, zfDYS, zgc:110165
list all antibodies Gene Name GeneID UniProt
DMD 1756 P11532
DMD 24907  
DMD 13405 P11531

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Most Popular Reactivities for anti-Dystrophin (DMD) Antibodies

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anti-Human Dystrophin Antibodies:

anti-Rat (Rattus) Dystrophin Antibodies:

anti-Mouse (Murine) Dystrophin Antibodies:

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Top referenced anti-Dystrophin Antibodies

  1. Fish Monoclonal Dystrophin Primary Antibody for ICC, IF - ABIN267904 : Morris, Ellis, Nguyen: A quantitative ELISA for dystrophin. in Journal of immunological methods 1993 (PubMed)
    Show all 8 references for ABIN267904

  2. Chicken Monoclonal Dystrophin Primary Antibody for IHC (p), WB - ABIN1107040 : Chelly, Hamard, Koulakoff, Kaplan, Kahn, Berwald-Netter: Dystrophin gene transcribed from different promoters in neuronal and glial cells. in Nature 1990 (PubMed)
    Show all 2 references for ABIN1107040

  3. Human Polyclonal Dystrophin Primary Antibody for ICC, IF - ABIN4306551 : Aoyama, Kawase, Bando, Monji, Murohara et al.: Dipeptidyl Peptidase 4 Inhibition Alleviates Shortage of Circulating Glucagon-Like Peptide-1 in Heart Failure and Mitigates Myocardial Remodeling and Apoptosis via the Exchange Protein Directly ... in Circulation. Heart failure 2016 (PubMed)
    Show all 2 references for ABIN4306551

  4. Chicken Monoclonal Dystrophin Primary Antibody for IHC (p), IHC - ABIN267033 : Hosur, Kavirayani, Riefler, Carney, Lyons, Gott, Cox, Shultz: Dystrophin and dysferlin double mutant mice: a novel model for rhabdomyosarcoma. in Cancer genetics 2012 (PubMed)
    Show all 2 references for ABIN267033

More Antibodies against Dystrophin Interaction Partners

Xenopus laevis Dystrophin (DMD) interaction partners

  1. Ordered disorder of the astrocytic dystrophin-associated protein complex in the norm and pathology.

Zebrafish Dystrophin (DMD) interaction partners

  1. Forced expression of embryonic dystrophin in zebrafish using an exon-skipping approach severely impairs the mobility and muscle architecture.

  2. Spatio-temporal differences in dystrophin dynamics at mRNA and protein levels have been revealed using a novel reporter system.

  3. Data indicate that ataluren (0.1-1 muM, 3-5 dpf) improved contractile function (~60% improvement of force at 0.5 muM) and dystrophin expression.

  4. Ordered disorder of the astrocytic dystrophin-associated protein complex in the norm and pathology.

  5. early expression of the short carboxyl-terminal dystrophin transcript, with expression of the full length muscle transcript occurring during myogenesis.

  6. Data suggest that dystrophin functions in regulation of calcium signaling during early stages of slow muscle cell differentiation; calcium signaling in these cells coincide with first spontaneous contractions of embryonic trunk.

  7. analysis of the dystrophin associated protein complex in zebrafish

  8. Data suggest that the progressive muscle degeneration phenotype of dystrophin mutant zebrafish embryos is caused by the failure of embryonic muscle end attachments.

  9. Dystrophin family gene expression in zebrafish is reported.

  10. reduction of dystrophin, dystroglycan (show DAG1 Antibodies) and sarcoglycan (show SGCD Antibodies) at translational level in embryos with overexpressed myostatin2

Fruit Fly (Drosophila melanogaster) Dystrophin (DMD) interaction partners

  1. Dys (show DAG1 Antibodies) protein regulates tarsal joint formation in response to Notch (show NOTCH1 Antibodies) activity during Drosophila leg development.

  2. The findings suggest that the signaling functions of Dystrophin protein are able to ameliorate dilated cardiomyopathy, and thus might help to improve heart muscle function in micro-Dystrophin-based gene therapy approaches.

  3. Nrk (show NRK Antibodies), mbl, capt and Cam (show CALM Antibodies) genetically interact with dystrophin and/or dystroglycan (show DAG1 Antibodies) in the process of axon path-finding in the eye.

  4. only dystroglycan (show DAG1 Antibodies), but not dystrophin deficiency causes myodegeneration induced by energetic stress suggesting that dystroglycan (show DAG1 Antibodies) might be a component of the low-energy pathway and act as a transducer of energetic stress in normal and dystrophic muscles

  5. Dystrophin and the Rho GTPase (show RACGAP1 Antibodies) crossveinless-c signaling pathway likely interact at the postsynaptic side of the NMJ to maintain synaptic homeostasis.

  6. Lack of the large dystrophin isoforms in the postsynaptic muscle cell leads to elevated evoked neurotransmitter release from presynaptic terminals.

  7. Our results indicate the existence of at least two possibly separate roles of dystrophin in muscle, maintaining synaptic homeostasis and preserving the structural stability of the muscle.

  8. The det locus encodes Drosophila dys, which acts with other components of the DAPC to influence intercellular signalling in developing wing veins.

  9. Possibility that Dp186 modulates other non-Gbb/Wit-dependent retrograde signaling pathways required to maintain normal synaptic physiology.

Human Dystrophin (DMD) interaction partners

  1. These data support the hypothesis that skewed XCI is involved in the onset of phenotype in DMD carriers, the X chromosome carrying the normal DMD gene being preferentially inactivated and leading to a moderate-severe muscle involvement.

  2. DMD reversion leads to somatic mosaicism in DMD patient.

  3. In this study, we focused on the phenotype of patients with BMD (show BEST1 Antibodies), who had in-frame deletion starting at exon 45 of the DMD gene, to investigate the appropriate restoration of the reading frame by exon skipping therapy

  4. It concluded that Dp71, comprising Dp71b and Dp71ab, was expressed exclusively in HEK293 cells and that Dp71ab was specifically localized to the nucleus. Our findings suggest that Dp71ab in the nucleus contributes to the diverse functions of HEK293 cells.

  5. This study aimed to provide in vitro quantitative evidence of the ability of human mesoangioblasts to restore dystrophin, in terms of protein accumulation and distribution, within myotubes derived from patients with Duchenne muscular dystrophy.

  6. In TMD patients, a novel locus at genome-wide level of significance (rs73460075, OR = 0.56, P = 3.8 x 10(-8)) in the intron of the dystrophin gene DMD (X chromosome), and a suggestive locus on chromosome 7 (rs73271865, P = 2.9 x 10(-7)) upstream of the Sp4 Transcription Factor ( SP4) gene were identified in the discovery cohort, but neither of these was replicated.

  7. As exon 44 skipping-amenable DMD has a later loss of ambulation, mutation-specific randomization and selection of placebo groups are essential for the success of clinical trials

  8. We focused on four prevalent mutated proteins deleted in RDelta45-47, RDelta45-48, RDelta45-49, and RDelta45-51, analyzing protein/membrane interactions. Mutants RDelta45-48 and RDelta45-51 led to mild pathologies and displayed a similar triple coiled-coil structure as the full-length DYS (show IKBKAP Antibodies) R16 (show SLC1A5 Antibodies)-21, whereas the two others, RDelta45-47 and RDelta45-49, induced more severe pathologies and showed "fractional" structures unre...

  9. The dystrophin expression plasmids described here will be useful in cell and gene therapy studies aimed at ameliorating Duchenne muscular dystrophy

  10. In Korean boys, 117 different deletions, 48 duplications, and 90 pathogenic sequence variations, including 30 novel variations, were identified. Deletions and duplications accounted for 65.4% and 13.3% of Korean dystrophinopathy, respectively, suggesting that the incidence of large rearrangements in dystrophin is similar among different ethnic groups.

Pig (Porcine) Dystrophin (DMD) interaction partners

  1. Data indicate that skeletal muscles from with a missense mutation in the dystrophin gene is associated with muscle histophatology.

Mouse (Murine) Dystrophin (DMD) interaction partners

  1. To optimize a dystrophin cDNA construct for therapeutic application we designed and produced four human minidystrophins within the packaging capacity of lentiviral vectors. Two novel minidystrophins retained the centrally located neuronal nitric oxide synthase (nNOS (show NOS1 Antibodies))-anchoring domain in order to achieve sarcolemmal nNOS (show NOS1 Antibodies) restoration, which is lost in most internally deleted dystrophin constructs.

  2. Our study demonstrates for the first time that low-level dystrophin can partially preserve heart function.

  3. Dp71 expression in hepatic cells is carried out, in part, by YY1 (show YY1 Antibodies)-, Sp1 (show SP1 Antibodies)- and Sp3 (show SP3 Antibodies)-mediated transcription from the Dp71 promoter.

  4. Deficit in cognitive flexibility was observed in mdx mice in the absence of motor dysfunction or general learning impairments.

  5. Our data also support the hypothesis that altered spatial localization of GABAA (show GABRg1 Antibodies) receptors due to Dp427 loss is a pathological mechanism associated with brain dysfunction in DMD, suggesting that extrasynaptic GABAA (show GABRg1 Antibodies) receptors might be candidate targets for future therapeutic developments.

  6. This finding represents the first functional evidence for a significant role of the dystrophin-associated protein complex in the regulation of Kir2.x channels.

  7. Lack of dystrophin in mdx mice appears associated with defective epithelial differentiation

  8. Dp71Delta78-79 dystrophin mutant stimulates neurite outgrowth in cultured neuronal cells via upregulation and phosphorylation of HspB1 (show HSPB1 Antibodies).

  9. this study provided evidence that the Dystrophin Dp71, a membrane-associated cytoskeletal protein (show DRP2 Antibodies) and the main DMD gene product in the retina, regulates astrocyte morphology and density and is associated with subsequent normal blood vessel development

  10. The novel dystrophin reporter mouse provides a valuable tool for direct visualization of dystrophin expression and will allow the study of dystrophin expression in vivo and in vitro in various tissues by live cell imaging.

Dystrophin (DMD) Antigen Profile

Antigen Summary

The dystrophin gene is the largest gene found in nature, measuring 2.4 Mb. The gene was identified through a positional cloning approach, targeted at the isolation of the gene responsible for Duchenne (DMD) and Becker (BMD) Muscular Dystrophies. DMD is a recessive, fatal, X-linked disorder occurring at a frequency of about 1 in 3,500 new-born males. BMD is a milder allelic form. In general, DMD patients carry mutations which cause premature translation termination (nonsense or frame shift mutations), while in BMD patients dystrophin is reduced either in molecular weight (derived from in-frame deletions) or in expression level. The dystrophin gene is highly complex, containing at least eight independent, tissue-specific promoters and two polyA-addition sites. Furthermore, dystrophin RNA is differentially spliced, producing a range of different transcripts, encoding a large set of protein isoforms. Dystrophin (as encoded by the Dp427 transcripts) is a large, rod-like cytoskeletal protein which is found at the inner surface of muscle fibers. Dystrophin is part of the dystrophin-glycoprotein complex (DGC), which bridges the inner cytoskeleton (F-actin) and the extra-cellular matrix.

Alternative names and synonyms associated with Dystrophin (DMD)

  • dystrophin (DMD) antibody
  • dystrophin (Dmd) antibody
  • dystrophin (dmd) antibody
  • Dystrophin (Dys) antibody
  • dystrophin, muscular dystrophy (Dmd) antibody
  • BMD antibody
  • cb664 antibody
  • CG7240 antibody
  • CG7243 antibody
  • CG7344 antibody
  • CG17750 antibody
  • CG31175 antibody
  • CG34157 antibody
  • CMD3B antibody
  • det antibody
  • DKFZp459C1629 antibody
  • DKFZp468A1620 antibody
  • DLP antibody
  • DLP1 antibody
  • DLP2 antibody
  • DLP3 antibody
  • DLP186 antibody
  • dmd antibody
  • dmDLP antibody
  • dmDp186 antibody
  • dmDys antibody
  • Dmel\\CG34157 antibody
  • DNADMD1 antibody
  • Dp71 antibody
  • Dp117 antibody
  • Dp186 antibody
  • Dp205 antibody
  • Dp427 antibody
  • DXS142 antibody
  • DXS164 antibody
  • DXS206 antibody
  • DXS230 antibody
  • DXS239 antibody
  • DXS268 antibody
  • DXS269 antibody
  • DXS270 antibody
  • DXS272 antibody
  • DXSmh7 antibody
  • DXSmh9 antibody
  • dys antibody
  • GI3046716 antibody
  • IDLP antibody
  • im:6911785 antibody
  • mdx antibody
  • MGC79631 antibody
  • MGC83347 antibody
  • pke antibody
  • RATDMD antibody
  • zfDYS antibody
  • zgc:110165 antibody

Protein level used designations for anti-Dystrophin (DMD) Antibodies

dystrophin , Duchenne muscular dystrophy , dystrophin isoform Dp116 , sap , sapje , CG34157-PA , CG34157-PB , CG34157-PC , CG34157-PD , CG34157-PE , CG34157-PF , CG34157-PG , CG34157-PH , CG34157-PI , CG34157-PJ , CG34157-PK , CG34157-PL , Dys-PA , Dys-PB , Dys-PC , Dys-PD , Dys-PE , Dys-PF , Dys-PG , Dys-PH , Dys-PI , Dys-PJ , Dys-PK , Dys-PL , Dystrophin-like protein 1 , Dystrophin-like protein 186 , Dystrophin-like protein 2 , Dystrophin-like protein 3 , detached , dystrophin Dp186 , dystrophin (muscular dystrophy, Duchenne and Becker types) , dystrophin Dp71 isoform , RNDNADMD1 , apodystrophin-3 , apodystrophin-I , dystrophin transcript variant Dp71e , dystrophin, muscular dystrophy , X-linked muscular dystrophy

GENE ID SPECIES
100051515 Equus caballus
708073 Macaca mulatta
399334 Xenopus laevis
100172693 Pongo abelii
465557 Pan troglodytes
493417 Xenopus (Silurana) tropicalis
100174396 Pongo abelii
100329118 Xenopus (Silurana) tropicalis
449606 Pan troglodytes
445738 Ciona intestinalis
83773 Danio rerio
42327 Drosophila melanogaster
100406331 Callithrix jacchus
1756 Homo sapiens
606758 Canis lupus familiaris
24907 Rattus norvegicus
396236 Gallus gallus
100727002 Cavia porcellus
497636 Sus scrofa
540755 Bos taurus
101119444 Ovis aries
13405 Mus musculus
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