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Jra recruits the HP1a (show CBX5 Antibodies)/KDM4A (show KDM4A Antibodies) complex to its gene body region upon osmotic stress to reduce H3K36 methylation levels and disrupt H3K36 methylation-dependent histone deacetylation
Data thus identify Atf3 (show ATF3 Antibodies) as a new functional partner of Drosophila Jun (show JUN Antibodies) during development.
Fos and Jun (show JUN Antibodies), the two components of AP1, are abundantly expressed in motor neurons; a model in which AP1 directly modulates NMJ plasticity processes through a cell autonomous pathway in the motor neuron is supported
Src (show SRC Antibodies), Jun N-terminal kinase (show MAPK8 Antibodies), and STAT (show STAT1 Antibodies) pathways are inhibited by Drosophila C-terminal Src kinase (show CSK Antibodies), which negatively regulates organ growth and cell proliferation
AP1 acts as a repressor by recruiting the deacetylase complex to terminate activation of a group of NF-kappaB target genes
We observed complex genetic interactions between mnn1 and jun (show JUN Antibodies) in different developmental settings. Our data support the idea that one function of menin (show MEN1 Antibodies) is to modulate Jun (show JUN Antibodies) activity in a manner dependent on the cellular context.
AP-1 mediated synapse enhancement and its relationship to increases in synapse number, Ca2 (show CA2 Antibodies)+ influx, Ca2 (show CA2 Antibodies)+ sensitivity of vesicle fusion or synaptic vesicle number, were examined.
Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGATCA-3'.
, Jun oncogene
, Jun related antigen
, activator protein 1
, complementation group V