Browse our RAB5 Proteins (RAB5A)

Full name:
RAB5A, Member RAS Oncogene Family Proteins (RAB5A)
On are 21 RAB5A, Member RAS Oncogene Family (RAB5A) Proteins from 9 different suppliers available. Additionally we are shipping RAB5 Antibodies (211) and RAB5 Kits (13) and many more products for this protein. A total of 253 RAB5 products are currently listed.
2410015H04Rik, AI663973, AU021172, DDBDRAFT_0168594, DDBDRAFT_0229401, DDB_0168594, DDB_0229401, nnyRab5a, RAB5, RAB5A
list all proteins Gene Name GeneID UniProt
RAB5A 5868 P20339
RAB5A 271457 Q9CQD1
Rat RAB5A RAB5A 64633  

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RAB5 Proteins (RAB5A) by Origin

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Top referenced RAB5 Proteins

  1. Human RAB5 Protein expressed in Escherichia coli (E. coli) - ABIN1686703 : Woodman: Biogenesis of the sorting endosome: the role of Rab5. in Traffic (Copenhagen, Denmark) 2001 (PubMed)
    Show all 4 references for 1686703

  2. Human RAB5 Protein expressed in Escherichia coli (E. coli) - ABIN666700 : Yao-Borengasser, Varma, Bodles, Rasouli, Phanavanh, Lee, Starks, Kern, Spencer, Rashidi, McGehee, Fried, Kern: Retinol binding protein 4 expression in humans: relationship to insulin resistance, inflammation, and response to pioglitazone. in The Journal of clinical endocrinology and metabolism 2007 (PubMed)
    Show all 2 references for 666700

More Proteins for RAB5 Interaction Partners

Human RAB5A, Member RAS Oncogene Family (RAB5A) interaction partners

  1. CMTM3 (show CMTM3 Proteins) decreases EGFR (show EGFR Proteins) expression, facilitates EGFR (show EGFR Proteins) degradation, and inhibits the EGF (show EGF Proteins)-mediated tumorigenicity of gastric cancer cells by enhancing Rab5 activity.

  2. High RAS-associated protein (show RGL2 Proteins) RAB5 expression correlated with the presence of lymphatic invasion and venous invasion and low E-cadherin (show CDH1 Proteins) expression.

  3. downregulated Rab5a led to slowed cell growth, decreased numbers of migrated cells, decreased numbers of cells at the G0G1 phase and a higher apoptosis rate. However, PDGF (show PDGFA Proteins) significantly rescued these phenomena caused by siRNA against Rab5a

  4. results suggest a new mechanism in which Rab5 induces a change in flexibility of EEA1 (show EEA1 Proteins), generating an entropic collapse force that pulls the captured vesicle towards the target membrane to initiate docking and membrane fusion

  5. structural differences may provide an opportunity to selectively target one Rab5 state and lead to new approaches in the development of Rab5-specific therapies

  6. Data show that rab5 GTP-Binding Protein (Rab5a) is overexpressed in human hepatocellular carcinoma (HCC (show FAM126A Proteins)) and contributes to cancer cell proliferation and invasion through regulation of FAK (show PTK2 Proteins) and AKT (show AKT1 Proteins) signaling.

  7. TTBK2 (show TTBK2 Proteins) down-regulates GluK2 (show GRIK2 Proteins) activity by decreasing the receptor protein abundance in the cell membrane via RAB5-dependent endocytosis.

  8. Results indicate that persistent rab5 overactivation through beta-cleaved carboxy-terminal fragment of APP (show APP Proteins)-APPL1 (show APPL1 Proteins) interactions constitutes a novel APP (show APP Proteins)-dependent pathogenic pathway in Alzheimer's disease

  9. Results demonstrate that DRG2 (show DRG2 Proteins) is an endosomal protein and a key regulator of Rab5 deactivation and Tfn (show Tf Proteins) recycling.

  10. Rab5a is involved in critical events not only at the beginning of the autophagy process with endosomal formation (initiation), but also later on, being important for autophagosome sealing and fusion with lysosomes through an interplay with Beclin 1 (show BECN1 Proteins).

Mouse (Murine) RAB5A, Member RAS Oncogene Family (RAB5A) interaction partners

  1. These data highlight a requirement of Rab5 and the endosomal system for the regulation of gluconeogenic gene expression that has important implications for metabolic diseases.

  2. Inpp5e (show INPP5E Proteins), through functional interactions with Rab20 (show RAB20 Proteins) on the phagosome, activates Rab5, which, in turn, increases PtdIns3P and delays phagosome acidification.

  3. FGF21 (show FGF21 Proteins) has a role in promoting endothelial cell angiogenesis through a dynamin-2 (show DNM2 Proteins) and Rab5 dependent pathway

  4. In silico screening for palmitoyl substrates reveals a role for DHHC1/3/10 (zDHHC1/3/11)-mediated neurochondrin (show NCDN Proteins) palmitoylation in its targeting to Rab5-positive endosomes.

  5. In mammalian cells, p110beta acts as a molecular sensor for growth factor availability and induces autophagy by activating a Rab5-mediated signaling cascade.

  6. Data show that Rinl is closely associated with the cytoskeleton and thus contributes to the spatial control of Rab5a and Rab22 signaling at actin-positive compartments.

  7. Data reveal the affinity of Rabex-5 (show RABGEF1 Proteins)/Rabaptin-5/Rab5-GTP (show AK3 Proteins) interaction in the cell, which is quantitatively related to the Rabex-5 (show RABGEF1 Proteins) concentration for the onset of the indirect

  8. Rab5 regulates and coordinates different endocytic mechanisms through its effector Rabankyrin-5 (show ANKFY1 Proteins)

  9. Using retroviral expression and siRNA Rab5a silencing, data demonstrate that Rab5a is essential for the large endosome phenotype and for localization of mannose receptor.

  10. the recruitment of Gapex-5 (show GAPVD1 Proteins) to phagosomes through the microtubule network induces transient Rab5 activation

Pig (Porcine) RAB5A, Member RAS Oncogene Family (RAB5A) interaction partners

  1. Expression of dominant negative Rab5 and Rab7 (show RAB7A Proteins) mutants, but not the dominant negative Rab11 (show RAB11A Proteins) mutant, significantly inhibited classical swine fever virus replication. These results were confirmed by silencing of Rab5 and Rab7 (show RAB7A Proteins).

  2. Dominant-negative mutant rab5 inhibits FMDV infection of IBRS-2 cells.

RAB5 (RAB5A) Protein Profile

Protein Summary

Required for the fusion of plasma membranes and early endosomes (By similarity).

Alternative names and synonyms associated with RAB5 (RAB5A)

  • rab5A protein (rab5A)
  • Rab5a, GTPase (Rab5a)
  • hypothetical protein (Rab5a)
  • Rab GTPase (rab5A)
  • Ras-related protein Rab-5A (rab5a)
  • ras-related protein rab-5a (rab5a)
  • RAB5A, member RAS oncogene family (rab5a)
  • RAB5A, member RAS oncogene family (RAB5A)
  • RAB5A, member RAS oncogene family (LOC100350923)
  • RAB5A, member RAS oncogene family (Rab5a)
  • 2410015H04Rik protein
  • AI663973 protein
  • AU021172 protein
  • DDBDRAFT_0168594 protein
  • DDBDRAFT_0229401 protein
  • DDB_0168594 protein
  • DDB_0229401 protein
  • nnyRab5a protein
  • RAB5 protein
  • RAB5A protein

Protein level used designations for RAB5A

rab5A protein , Rab5a, GTPase , hypothetical protein , Ras-related protein Rab-5A , ras-related protein rab-5a , RAB5A, member RAS oncogene family , ras-related protein Rab-5A , RAS-associated protein RAB5A , small GTP-binding protein rab5 , GTP-binding protein (rab5)

553894 Lotus japonicus
812700 Plasmodium falciparum 3D7
7197170 Phaeodactylum tricornutum CCAP 1055/1
8618246 Dictyostelium discoideum AX4
100195116 Salmo salar
100528297 Ictalurus punctatus
380227 Xenopus laevis
460217 Pan troglodytes
697712 Macaca mulatta
699014 Macaca mulatta
100350923 Oryctolagus cuniculus
5868 Homo sapiens
271457 Mus musculus
64633 Rattus norvegicus
404008 Canis lupus familiaris
539764 Bos taurus
100144499 Sus scrofa
420649 Gallus gallus
101099995 Felis catus
100302084 Ovis aries
100723790 Cavia porcellus
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