Browse our EOMES Proteins (EOMES)

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Eomesodermin Proteins (EOMES)
On are 4 Eomesodermin (EOMES) Proteins from 2 different suppliers available. Additionally we are shipping EOMES Antibodies (92) and EOMES Kits (6) and many more products for this protein. A total of 110 EOMES products are currently listed.
C77258, eom, eomes, TBR-2, Tbr2, xeomes
list all proteins Gene Name GeneID UniProt
EOMES 8320 O95936
Rat EOMES EOMES 316052  
EOMES 13813 O54839

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EOMES Proteins (EOMES) by Origin

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More Proteins for EOMES Interaction Partners

Zebrafish Eomesodermin (EOMES) interaction partners

  1. Smad2 (show SMAD2 Proteins) and Eomesodermin a (Eomesa) bind common genomic regions proximal to genes involved in mesoderm and endoderm formation, suggesting Eomesa forms a general component of the Smad2 (show SMAD2 Proteins) signalling complex in zebrafish.

  2. Eomesa has a strictly maternal role in the initiation of epiboly, and is required for normal expression of the endoderm markers sox32, bon and og9x (show SEBOX Proteins); however it is not essential for endoderm formation.

  3. Eomes is a Nodal-transducing factor that acts, directly and indirectly, in concert with FoxH1 (show FOXH1 Proteins) to carry out all Nodal-dependent processes during early mesendoderm specification.

  4. Eomes plays a role in specifying the embryonic organizer.

  5. regulates the expression of a zygotic homeobox (show PRRX1 Proteins) transcription factor mtx2 (show MTX2 Proteins)

  6. Results suggest that eomesodermin promotes endoderm induction in marginal blastomeres by facilitating the assembly of a transcriptional activating complex on the casanova promoter.

  7. These results suggest that both Eomes genes are involved in the zebrafish immune response, particularly in lymphocyte function as has been found in mammals.

Pig (Porcine) Eomesodermin (EOMES) interaction partners

  1. the expression of T-bet, Eomes and GATA-3 (show GATA3 Proteins) in combination with additional differentiation molecules within CD4 (show CD4 Proteins)+ and CD8beta+ T cell subsets from different organs of healthy pigs.

Human Eomesodermin (EOMES) interaction partners

  1. Reciprocal regulation of BMF (show BMF Proteins) and BIRC5 (show BIRC5 Proteins) is linked to Eomes overexpression in colorectal cancer.

  2. Eomes(hi) NK cells can be recruited from the circulation during adult life and that circulating Eomes(lo) NK cells are able to upregulate Eomes and molecules mediating liver retention under cytokine conditions similar to those in the liver.

  3. EOMES expression was low in multiple sclerosis (MS), and stable over time. The low EOMES/TBX21 phenotype in MS reflects cd56 (show NCAM1 Proteins)+ cell dysregulation.

  4. we identified a higher Eomes mRNA expression as an independent good prognostic factor for OS and PFS in mRCC patients treated with sorafenib.

  5. Eomes(+) CD4(+) T cells are increased in the peripheral blood and cerebrospinal fluid from patients in a progressive state of multiple sclerosis.

  6. the level of T-bet and Eomesodermin, two T-box transcription factors regulating lymphocyte effector functions, is strongly reduced in NK cells from allogeneic hematopoietic stem cell transplantation recipients compared with healthy control subjects.

  7. This study showed that EOMES (rs2724509; flanking) associated with Alzheimer disease.

  8. This study supports the concept that poor human viral-specific CD8 (show CD8A Proteins)(+) T cell functionality is due to an inverse expression balance between T-bet and Eomes

  9. Report a global loss of 5hmC identified three new genes (ECM1 (show ECM1 Proteins), ATF5 (show ATF5 Proteins), and EOMES) with potential anti-cancer functions that may promote the understanding of the molecular mechanisms of hepatocellular carcinoma development and progression.

  10. HHEX (show HHEX Proteins) promotes hepatic specification by repressing EOMES expression.

Cow (Bovine) Eomesodermin (EOMES) interaction partners

  1. as conceptuses attach to the uterine epithelium, IFNT gene transcription is down-regulated by an increase in EOMES expression and EOMES-CREBBP (show CREBBP Proteins) binding in the attached trophoblast cells.

Mouse (Murine) Eomesodermin (EOMES) interaction partners

  1. HDAC11-knockout T cells displayed enhanced proliferation, proinflammatory cytokine production, and effector molecule expression of Eomes and TBX21 transcription factors previously shown to regulate inflammatory cytokine and effector molecule production.

  2. increases the number of ALP (show CCL21A Proteins)-positive colonies after iPSC induction and decreases expression levels of Eomes and p21 mRNAs. Based on these observations, we propose that the CCR4 (show CCR4 Proteins)-NOT deadenylase activity contributes to iPSC induction.

  3. Results indicated that Eomes bound to the Ifng (show IFNG Proteins) promoter and multiple conserved noncoding sequences in stimulation-dependent and stimulation-independent manners.

  4. Demonstrate by using the T-box brain-2(Cre) mouse line that progenitor cells derived cells contribute 67.5% of glutamatergic but not GABAergic or astrocytic cells to all cortical layers including the earliest generated subplate zone.

  5. a critical role for IRF4 (show IRF4 Proteins) in regulating protective anti-viral CD8 (show CD8A Proteins)+ T cell responses by ensuring a balanced ratio of T-bet to Eomes

  6. Eomes expression is a key determinant of conventional NK versus Type 1 helper Innate Lymphoid Cell maturation following lineage specification.

  7. T-cell-specific deletion of the Eomes gene remarkably ameliorates the late-onset experimental autoimmune encephalomyelitis.

  8. find that while stimulation of CD27 (show CD27 Proteins) in isolation drives weak Eomesodermin(hi) T-bet(lo) CD8 (show CD8A Proteins)(+) T-cell responses to OVA immunization

  9. The data identify a novel role for Eomes in CD4 (show CD4 Proteins)+ T cells and indicate that Eomes expression may act by limiting Foxp3 (show FOXP3 Proteins) induction, which may contribute to the association of EOMES to susceptibility to multiple sclerosis.

  10. type I interferon (show IFNA Proteins) signalling in CD8 (show CD8A Proteins)(+) T cells drives Eomes expression.

EOMES Protein Profile

Protein Summary

This gene encodes a member of a conserved protein family that shares a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. A similiar gene disrupted in mice is shown to be essential during trophoblast development and gastrulation.

Alternative names and synonyms associated with EOMES

  • eomesodermin homolog (Xenopus laevis) (EOMES)
  • eomesodermin (eomes)
  • eomesodermin homolog a (eomesa)
  • eomesodermin homolog (LOC100470077)
  • eomesodermin (EOMES)
  • eomesodermin homolog (LOC100545637)
  • eomesodermin homolog (LOC100602343)
  • eomesodermin homolog (LOC100622125)
  • eomesodermin (Eomes)
  • eomesodermin homolog (Xenopus laevis) (Eomes)
  • C77258 protein
  • eom protein
  • eomes protein
  • TBR-2 protein
  • Tbr2 protein
  • xeomes protein

Protein level used designations for Eomesodermin Proteins (EOMES)

eomesodermin homolog (Xenopus laevis) , eomesodermin , eom-a , eomes1 , eomesodermin homolog , tbr2 , tbr2a , T-box brain protein 2 , T-brain-2

428443 Gallus gallus
470774 Pan troglodytes
100038065 Xenopus (Silurana) tropicalis
100051187 Equus caballus
100431463 Pongo abelii
100532741 Salmo salar
64603 Danio rerio
100470077 Ailuropoda melanoleuca
100524218 Sus scrofa
100545637 Meleagris gallopavo
100602343 Nomascus leucogenys
100622125 Sus scrofa
8320 Homo sapiens
485636 Canis lupus familiaris
316052 Rattus norvegicus
511947 Bos taurus
398065 Xenopus laevis
13813 Mus musculus
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