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anti-Human LIM Domain Binding 2 Protein Antibodies:
anti-Mouse (Murine) LIM Domain Binding 2 Protein Antibodies:
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LDB2 wa (show LDLR Antibodies)s the most co (show APOB Antibodies)nnected gene in a transcription factor regulatory network inferred from transendothelial migration of leukocyte and atherosclerosis module genes in coronary and carotid artery disease macrophages.
The transcription co-factor LIM domain binding 2 (LDB2) was identified as a potential high-hierarchy regulator of the atherosclerosis-module.
Results show that CLP36 is accumulated in Atg7 (show ATG7 Antibodies)-deficient cardiomyocytes, and suggest that autophagy may protect cardiomyocytes from the ischemia-reperfusion injury through the clearance of CLP36.
An intricate regulatory network exists that is mediated by Ldb1 (show LDB1 Antibodies) and Ldb2, and promotes retinal progenitor cells proliferation and multipotency; it also controls specification of mammalian retina cells.
CLIM interacts with estrogen receptor alpha (show ESR1 Antibodies) at the H19 (show NCKAP1 Antibodies) locus, potentially explaining the higher expression of H19 (show NCKAP1 Antibodies) in female than male corneas.
In Ldlr (show LDLR Antibodies)(-/-)Apob(100 (show APOB Antibodies)/100) mice, loss of Ldb2 increased atherosclerotic lesion size approximately 2-fold and decreased plaque stability.
Isl1 (show ISL1 Antibodies) and the Ldb co-regulators of transcription are essential early determinants of mouse limb development
Data show an inhibitory function of CLP-36 in GPVI (show GP6 Antibodies) immunoreceptor tyrosine-based activation motif signaling and as a key regulator of arterial thrombosis.
Data suggest that Ldb1 (show LDB1 Antibodies)/2 function to maintain SLK (show SLK Antibodies) in an inactive state before its activation.
results indicate that alpha-actinin, CLP36 and palladin form a protein complex and contribute to regulation of the actin cytoskeleton
splice isoforms lacking the LIm (show PDLIM5 Antibodies)-interaction domain are present in the Ldb1 (show LDB1 Antibodies) genes of mammals, chick, and Xenopus.
The fine tuning of TGF-beta (show TGFB1 Antibodies) signaling derives from positive and negative control by Ldb2a.
Genes encoding LIM domain-binding factors were initially isolated in a screen for proteins that physically interact with the LIM domains of nuclear proteins (summarized by Semina et al., 1998
LIM domain binding 2
, LIM domain-binding protein 2-like
, LIM domain binding protein CLIM-1
, LIM domain-binding factor CLIM1
, LIM domain-binding protein 2
, carboxyl-terminal LIM domain-binding protein 1
, LIM binding domain 2
, LIM domain-binding factor-2
, LIM-domain-binding protein 2a
, LIM-domain-binding protein 2b
, LIM-domain binding factor 2