Browse our NKAP Proteins (NKAP)

Full name:
NFKB Activating Protein Proteins (NKAP)
On www.antibodies-online.com are 3 NFKB Activating Protein (NKAP) Proteins from 2 different suppliers available. Additionally we are shipping NKAP Antibodies (26) and NKAP Kits (19) and many more products for this protein. A total of 51 NKAP products are currently listed.
Synonyms:
2610020o08rik, AA987160, AI849147, AL024236
list all proteins Gene Name GeneID UniProt
NKAP 79576 Q8N5F7
NKAP 67050 Q9D0F4
NKAP 298342 Q4V7C9

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NKAP Proteins (NKAP) by Origin

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Human NFKB Activating Protein (NKAP) interaction partners

  1. NKAP is required for T cell maturation and the acquisition of functional competency

  2. NKAP is a novel nuclear regulator of TNF (show TNF Proteins)- and IL-1 (show IL1A Proteins)-induced NF-kappaB (show NFKB1 Proteins) activation

  3. NKAP functions as a transcriptional repressor, acting on Notch (show NOTCH1 Proteins) target genes, and is required for alphabeta T cell development.

Mouse (Murine) NFKB Activating Protein (NKAP) interaction partners

  1. NKAP regulates multiple steps in Invariant NKT (show CTSL1 Proteins) cell development and differentiation.

  2. we provide first evidence for the expression of NKAP in neurogenic cells of the adult mammalian brain

  3. Transcriptional repressor NKAP is required for invariant natural killer T cell but not conventional T cell development.

  4. NKAP is required for T cell maturation and the acquisition of functional competency

  5. Inducible deletion of NKAP in adult mice leads to lethality within 2 weeks, at which point hematopoiesis in the bone marrow has halted and hematopoietic stem cells have disappeared.

  6. NKAP is a novel nuclear regulator of TNF (show TNF Proteins)- and IL-1 (show IL1A Proteins)-induced NF-kappaB (show NFKB1 Proteins) activation

  7. NKAP functions as a transcriptional repressor, acting on Notch (show NOTCH1 Proteins) target genes, and is required for alphabeta T cell development.

NKAP Protein Profile

Protein Summary

This gene encodes a protein that is involved in the activation of the ubiquitous transcription factor NF-kappaB. This protein is associated with the the histone deacetylase HDAC3 and with the Notch corepressor complex, and it thereby acts as a transcriptional repressor of Notch target genes. It is also required for alphabeta T cell development. A related pseudogene has been identified on chromosome X, while a related and intronless retrocopy, which has an intact CDS and may be functional, is located on chromosome 6.

Alternative names and synonyms associated with NKAP

  • NFKB activating protein (NKAP)
  • NFKB activating protein (Nkap)
  • 2610020o08rik protein
  • AA987160 protein
  • AI849147 protein
  • AL024236 protein

Protein level used designations for NFKB Activating Protein Proteins (NKAP)

NF-kappa-B-activating protein , NF-kappaB activating protein , nuclear NF-kappaB activating protein

GENE ID SPECIES
79576 Homo sapiens
67050 Mus musculus
298342 Rattus norvegicus
492098 Canis lupus familiaris
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