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Browse our anti-SMC1A (SMC1A) Antibodies

Full name:
anti-Structural Maintenance of Chromosomes 1A Antibodies (SMC1A)
On www.antibodies-online.com are 236 Structural Maintenance of Chromosomes 1A (SMC1A) Antibodies from 27 different suppliers available. Additionally we are shipping SMC1A Kits (7) and SMC1A Proteins (4) and many more products for this protein. A total of 250 SMC1A products are currently listed.
Synonyms:
5830426I24Rik, CDLS2, DXS423E, im:7158706, mKIAA0178, NV15570, Sb1.8, SMC-1A, smc1, smc1a, smc1aa, Smc1alpha, Smc1l1, SMC1L2, Smcb, xSMC1, zgc:76902
list all antibodies Gene Name GeneID UniProt
SMC1A 8243 Q14683
SMC1A 24061 Q9CU62
SMC1A 63996 Q9Z1M9

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Top referenced anti-SMC1A Antibodies

  1. Human Polyclonal SMC1A Primary Antibody for ELISA, ICC - ABIN151508 : Udayakumar, Bladen, Hudson, Dynan: Distinct pathways of nonhomologous end joining that are differentially regulated by DNA-dependent protein kinase-mediated phosphorylation. in The Journal of biological chemistry 2003 (PubMed)
    Show all 30 references for ABIN151508

  2. Human Polyclonal SMC1A Primary Antibody for IP, PLA - ABIN151518 : Bekker-Jensen, Lukas, Kitagawa, Melander, Kastan, Bartek, Lukas: Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks. in The Journal of cell biology 2006 (PubMed)
    Show all 21 references for ABIN151518

  3. Human Polyclonal SMC1A Primary Antibody for ELISA, ICC - ABIN151528 : Leung-Pineda, Ryan, Piwnica-Worms: Phosphorylation of Chk1 by ATR is antagonized by a Chk1-regulated protein phosphatase 2A circuit. in Molecular and cellular biology 2006 (PubMed)
    Show all 7 references for ABIN151528

  4. Human Polyclonal SMC1A Primary Antibody for IHC (p) - ABIN196936 : Yang, Mehta, Uzri, Jayaram, Velmurugan: Mutations in a partitioning protein and altered chromatin structure at the partitioning locus prevent cohesin recruitment by the Saccharomyces cerevisiae plasmid and cause plasmid missegregation. in Molecular and cellular biology 2004 (PubMed)
    Show all 3 references for ABIN196936

  5. Human Polyclonal SMC1A Primary Antibody for IHC (p) - ABIN197408 : Kim, Xu, Kastan: Involvement of the cohesin protein, Smc1, in Atm-dependent and independent responses to DNA damage. in Genes & development 2002 (PubMed)
    Show all 3 references for ABIN197408

  6. Human Polyclonal SMC1A Primary Antibody for IP, WB - ABIN318942 : Jones, Sgouros: The cohesin complex: sequence homologies, interaction networks and shared motifs. in Genome biology 2001 (PubMed)
    Show all 2 references for ABIN318942

  7. Chicken Polyclonal SMC1A Primary Antibody for WB - ABIN2780766 : Barber, McManus, Yuen, Reis, Parmigiani, Shen, Barrett, Nouhi, Spencer, Markowitz, Velculescu, Kinzler, Vogelstein, Lengauer, Hieter: Chromatid cohesion defects may underlie chromosome instability in human colorectal cancers. in Proceedings of the National Academy of Sciences of the United States of America 2008 (PubMed)

  8. Human Monoclonal SMC1A Primary Antibody for FACS, IHC - ABIN488213 : Paech, Webb, Kuiper, Nilsson, Gustafsson, Kushner, Scanlan: Differential ligand activation of estrogen receptors ERalpha and ERbeta at AP1 sites. in Science (New York, N.Y.) 1997 (PubMed)

  9. Human Monoclonal SMC1A Primary Antibody for ICC, FACS - ABIN969406 : Kim, Choi, Kim, Woo, Chung: Reoxygenation following hypoxia activates DNA-damage checkpoint signaling pathways that suppress cell-cycle progression in cultured human lymphocytes. in FEBS letters 2007 (PubMed)

More Antibodies against SMC1A Interaction Partners

Zebrafish Structural Maintenance of Chromosomes 1A (SMC1A) interaction partners

  1. zebrafish embryos and SMC1A-mutated pa (show NIPBL Antibodies)tient-derived fibroblasts were used to analyze abnormalities induced by SMC1A loss of function

Human Structural Maintenance of Chromosomes 1A (SMC1A) interaction partners

  1. High SMC1A expression is associated with prostate cancer.

  2. Results showed that the high expression of SMC1 often promoted epithelial-mesenchymal transition, accompanied by the enhanced expression of Brachyury (show TBX1 Antibodies) in triple-negative breast cancer cells.

  3. SMC1A plays an oncogenic role in colorectal cancer.

  4. Loss-of-function mutations of SMC1A may be associated with early-onset encephalopathy with epilepsy.

  5. numerous dysregulated genes occupied by cohesin by combining the transcriptome of CdLS (show NIPBL Antibodies) cell lines carrying mutations in SMC1A gene, were identified.

  6. two novel de novo heterozygous frameshift mutations in the SMC1A gene were identified in two patients with developmental delay and epilepsy.

  7. Our findings identify both SMC1 and CTCF (show CTCF Antibodies) as critical regulators of the differentiation-dependent life cycle of high-risk human papillomaviruses

  8. same down-regulation of cohesin target (show NIPBL Antibodies)s is observed in SMC1A-mutated patient fibroblasts

  9. Results show that SMC1A is overexpressed in colorectal cancer tissues and correlated with poor prognosis for late stage disease.

  10. The SMC1a mutation leads to chromosomal instability and tumorigenesis in early colorectal adenomas.

Mouse (Murine) Structural Maintenance of Chromosomes 1A (SMC1A) interaction partners

  1. expression analysis of Smc1a and Nipbl (show NIPBL Antibodies) in developing mouse embryos reveals a specific pattern in the hindbrain

  2. SMC1A participates in tissue-specific enhancer-promoter interactions and interactions that demarcate regions of correlated regulatory output.

  3. Point mutation at the Nbs1 (show NBN Antibodies) Threonine 278 site does not affect mouse development, but compromises the Chk2 (show CHEK2 Antibodies) and Smc1 phosphorylation after DNA damage.

  4. A positively charged channel within the Smc1/Smc3 (show SMC3 Antibodies) hinge required for sister chromatid cohesion.

  5. SMC1alpha is mainly associated with homologous or non-homologous synapsed regions. The protein also localizes along meiotic chromosome cores of Spo11 (show SPO11 Antibodies) null spermatocytes.

  6. observations suggest that many of the abnormal stress responses seen in cells lacking ATM (show ATM Antibodies), NBS1 (show NBN Antibodies), or BRCA1 (show BRCA1 Antibodies) result from a failure of ATM (show ATM Antibodies) migration to sites of DNA breaks and a resultant lack of SMC1 phosphorylation.

  7. SMC1beta (show SMC1B Antibodies) was found along the axial elements of synaptonemal complexes in prophase I of testis sections and chromosome spreads . Thus, SMC1beta (show SMC1B Antibodies) and not SMC1alpha is likely involved in maintaining cohesion between sister centromeres until anaphase II.

Cow (Bovine) Structural Maintenance of Chromosomes 1A (SMC1A) interaction partners

SMC1A Antigen Profile

Antigen Summary

Proper cohesion of sister chromatids is a prerequisite for the correct segregation of chromosomes during cell division. The cohesin multiprotein complex is required for sister chromatid cohesion. This complex is composed partly of two structural maintenance of chromosomes (SMC) proteins, SMC3 and either SMC1L2 or the protein encoded by this gene. Most of the cohesin complexes dissociate from the chromosomes before mitosis, although those complexes at the kinetochore remain. Therefore, the encoded protein is thought to be an important part of functional kinetochores. In addition, this protein interacts with BRCA1 and is phosphorylated by ATM, indicating a potential role for this protein in DNA repair. This gene, which belongs to the SMC gene family, is located in an area of the X-chromosome that escapes X inactivation.

Alternative names and synonyms associated with SMC1A

  • structural maintenance of chromosomes 1A, like (smc1al) antibody
  • structural maintenance of chromosomes 1A (SMC1A) antibody
  • structural maintenance of chromosomes 1B (SMC1B) antibody
  • SMC1 structural maintenance of chromosomes 1-like 2 (LOC100337867) antibody
  • structural maintenance of chromosomes 1A (Smc1a) antibody
  • structural maintenance of chromosomes 1A (smc1a) antibody
  • structural maintenance of chromosomes 1A b (smc1ab) antibody
  • 5830426I24Rik antibody
  • CDLS2 antibody
  • DXS423E antibody
  • im:7158706 antibody
  • mKIAA0178 antibody
  • NV15570 antibody
  • Sb1.8 antibody
  • SMC-1A antibody
  • smc1 antibody
  • smc1a antibody
  • smc1aa antibody
  • Smc1alpha antibody
  • Smc1l1 antibody
  • SMC1L2 antibody
  • Smcb antibody
  • xSMC1 antibody
  • zgc:76902 antibody

Protein level used designations for SMC1A

SMC1 structural maintenance of chromosomes 1-like 1 , SMC1 structural maintenance of chromosomes 1-like 2 , structural maintenance of chromosomes 1A , structural maintenance of chromosomes protein 1A-like , SMC protein 1A , SMC-1-alpha , SMC1 (structural maintenance of chromosomes 1, yeast)-like 1 , segregation of mitotic chromosomes 1 , structural maintenance of chromosomes protein 1A , SMC (segregation of mitotic chromosomes 1)-like 1 , chromosome segregation protein SmcB , segregation of mitotic chromosomes b , SMC-like 1 , structural maintenance of chromosomes 1A a , SMC1 protein cohesin subunit , structural maintenance of chromosomes 1 , SMC-protein , DXhXs423e , segregation of mitotic chromosomes-like 1 , structural maintenance of chromosomes 1 like 1 , 14S cohesin SMC1 subunit

GENE ID SPECIES
403060 Danio rerio
677711 Macaca mulatta
418243 Gallus gallus
458907 Pan troglodytes
100337867 Oryctolagus cuniculus
473619 Pan troglodytes
100120122 Nasonia vitripennis
100402111 Callithrix jacchus
100458659 Pongo abelii
8243 Homo sapiens
24061 Mus musculus
559665 Danio rerio
380182 Xenopus laevis
395187 Gallus gallus
480928 Canis lupus familiaris
282370 Bos taurus
63996 Rattus norvegicus
100379087 Xenopus laevis
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