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Browse our SMC3 (SMC3) ELISA Kits

Full name:
Structural Maintenance of Chromosomes 3 ELISA Kits (SMC3)
On www.antibodies-online.com are 0 Structural Maintenance of Chromosomes 3 (SMC3) ELISA Kits from different suppliers available. Additionally we are shipping SMC3 Antibodies (87) and SMC3 Proteins (6) and many more products for this protein. A total of 99 SMC3 products are currently listed.
Synonyms:
BAM, bamacan, BMH, CDLS3, Cspg6, HCAP, im:7142991, Mmip1, SMC-3, SMC3L1, SmcD, wu:fb22e01, wu:fc30d07, xsmc3
list all ELISA KIts Gene Name GeneID UniProt
Human SMC3 SMC3 9126 Q9UQE7
Mouse SMC3 SMC3 13006 Q9CW03
Rat SMC3 SMC3 29486  

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More ELISA Kits for SMC3 Interaction Partners

Human Structural Maintenance of Chromosomes 3 (SMC3) interaction partners

  1. We identified a large number of mutations in the CC region of both Smc1 (show SMC1A ELISA Kits) and Smc3... we introduced them to the yeast Smc1 (show SMC1A ELISA Kits) and Smc3 CC domains and characterized the effect of these mutant alleles on cohesin's function. We identified a missense mutation in the region of the kink domain of Smc3, which was previously identified in kidney carcinoma

  2. Results show that SMC3 is upregulated in asthma patients and suggest that it may play an important role in atopic asthma development, especially in asthma epithelial-mesenchymal transition.

  3. Data show that histone deacetylase 8 (HDAC8 (show HDAC8 ELISA Kits)) inhibition led to accumulation of acetylated-SMC3 protein but had no influence on the transcription of estrogen-responsive genes.

  4. De novo heterozygous mutations in SMC3 cause a range of Cornelia de Lange syndrome-overlapping phenotypes

  5. cohesin's proposed DNA exit gate is formed by interactions between Scc1 (show PTPRJ ELISA Kits) and the coiled-coil region of Smc3.

  6. Cross-sectional deep-sequencing analysis for clonal hierarchy demonstrated STAG2, SMC3, and RAD21 (show RAD21 ELISA Kits) mutations to be ancestral in 18%, 18%, and 47% of cases, respectively, and each expanded to clonal dominance concordant with disease transformation

  7. Mutations in SMC3 is associated with acute myeloid leukemia (show BCL11A ELISA Kits).

  8. Upon knock-down of human SMC1, much of SMC3 remains stable, accumulates in the cytoplasm and does not associate with other cohesin proteins.

  9. c-MYC (show MYC ELISA Kits) down-regulation caused by cohesin mutations in SMC1A (show SMC1A ELISA Kits) and SMC3 genes may be an early/primary event in the pathogenesis of Cornelia de Lange syndrome.

  10. NIPBL (show NIPBL ELISA Kits), SMC1A (show SMC1A ELISA Kits), and SMC3 mutation-positive patients were equally likely to have congenital heart diseases in Cornelia de lange syndrome.

Mouse (Murine) Structural Maintenance of Chromosomes 3 (SMC3) interaction partners

  1. A positively charged channel within the Smc1 (show SMC1A ELISA Kits)/Smc3 hinge required for sister chromatid cohesion.

Xenopus laevis Structural Maintenance of Chromosomes 3 (SMC3) interaction partners

  1. XEco2 (show ESCO2 ELISA Kits) is the cohesin acetyltransferase responsible for Smc3 acetylation.

  2. Endogenous SMC3 and newly expressed hRAD21 (show RAD21 ELISA Kits) co-localize on chromosomal axes, sites where sister chromatids are tightly paired. hRAD21 (show RAD21 ELISA Kits) recruitment to lampbrush chromosomes is modulated by chromosomal SMC1 (show SMC1A ELISA Kits) and SMC3.

SMC3 Antigen Profile

Antigen Summary

This gene belongs to the SMC3 subfamily of SMC proteins. The encoded protein occurs in certain cell types as either an intracellular, nuclear protein or a secreted protein. The nuclear form, known as structural maintenance of chromosomes 3, is a component of the multimeric cohesin complex that holds together sister chromatids during mitosis, enabling proper chromosome segregation. Post-translational modification of the encoded protein by the addition of chondroitin sulfate chains gives rise to the secreted proteoglycan bamacan, an abundant basement membrane protein.

Alternative names and synonyms associated with SMC3

  • structural maintenance of chromosomes 3 (smc3) Elisa Kit
  • structural maintenance of chromosomes 3 (SMC3) Elisa Kit
  • structural maintenance of chromosomes 3 (Smc3) Elisa Kit
  • BAM Elisa Kit
  • bamacan Elisa Kit
  • BMH Elisa Kit
  • CDLS3 Elisa Kit
  • Cspg6 Elisa Kit
  • HCAP Elisa Kit
  • im:7142991 Elisa Kit
  • Mmip1 Elisa Kit
  • SMC-3 Elisa Kit
  • SMC3L1 Elisa Kit
  • SmcD Elisa Kit
  • wu:fb22e01 Elisa Kit
  • wu:fc30d07 Elisa Kit
  • xsmc3 Elisa Kit

Protein level used designations for SMC3

chondroitin sulfate proteoglycan 6 (bamacan) , SMC protein 3 , basement membrane-associated chondroitin proteoglycan , chromosome-associated polypeptide , structural maintenance of chromosomes protein 3 , chondroitin sulfate proteoglycan 6 , chromosome segregation protein SmcD , mad member-interacting protein 1 , structural maintenace of chromosomes 3 , cohesin complex subunit , bamacan , basement membrane chondroitin sulfate proteoglycan

GENE ID SPECIES
100145671 Xenopus (Silurana) tropicalis
9126 Homo sapiens
13006 Mus musculus
324475 Danio rerio
399092 Xenopus laevis
395188 Gallus gallus
486886 Canis lupus familiaris
281729 Bos taurus
29486 Rattus norvegicus
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