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Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 ELISA Kits (SPI1)
On www.antibodies-online.com are 9 Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 (SPI1) ELISA Kits from 7 different suppliers available. Additionally we are shipping Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 Antibodies (152) and Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 Proteins (11) and many more products for this protein. A total of 183 Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 products are currently listed.
Synonyms:
2B1, Ab1-021, cb1086, CPi-23, Dis-1, Dis1, Gm5657, OF, pu.1, pu1, Serpina3d, Serpina3l, Sfpi-1, sfpi1, si:by184l24.2, Spi-1, SPI-A, SPI1, Spin1, Spin2a, Tcfpu1, Tfpu.1
list all ELISA KIts Gene Name GeneID UniProt
SPI1 435318  
SPI1 299282  
SPI1 6688 P17947

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Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 (SPI1) ELISA Kits by Reactivity

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More ELISA Kits for Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 Interaction Partners

Mouse (Murine) Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 (SPI1) interaction partners

  1. These studies reveal an important role for PU.1 in the regulation of Igkappa transcription and rearrangement and a requirement for PU.1 and Spi-B (show SPIB ELISA Kits) in B cell development.

  2. expression of an essential mediator of neutrophil terminal differentiation, the ets transcription factor PU.1, was significantly decreased in Hbb (show HBB ELISA Kits)(th3/+) neutrophils in a model of beta-thalassemia

  3. Moreover, the expression of a cell proliferation marker Ki67 (show MKI67 ELISA Kits) was significantly decreased in tumors from the mice not taking doxycycline, compared with that of tumors from the mice continuously taking doxycycline. The present data strongly suggest that PU.1 functions as a tumor suppressor of myeloma cells in vivo.

  4. the affinities of two sequence-divergent ETS (show ETS1 ELISA Kits) homologs, PU.1 and Ets-1 (show ETS1 ELISA Kits), to DNA sites harboring a hemi- and fully methylated CpG dinucleotide, were measured.

  5. this study shows that PU.1 functions as a positive regulator of CD11c (show ITGAX ELISA Kits) gene expression by directly binding to the Itgax (show ITGAX ELISA Kits) promoter and through transactivation of the Irf4 (show IRF4 ELISA Kits) gene

  6. Here we demonstrate that the transcription factors SPI1 (PU.1) and HOXC13 synergistically regulate Zfp521 expression, and identify the regions of the Zfp521 promoter required for this transcriptional activity. We also show that SPI1 and HOXC13 activate Zfp521 in a dose-dependent manner.

  7. findings suggest that Gata1 (show GATA1 ELISA Kits) & PU.1 transcription factors are only executing and reinforcing lineage choice once made. These results challenge the current prevailing model of early myeloid lineage choice

  8. involved in osteoclast development by transactivating NFATc1 (show NFATC1 ELISA Kits) expression via direct binding to the NFATc1 (show NFATC1 ELISA Kits) promoter

  9. GATA1 (show GATA1 ELISA Kits) and PU.1 bind in vitro and in vivo the proximal promoter region of the RPS19 (show RPS19 ELISA Kits) gene which is frequently mutated in Diamond-Blackfan Anemia.

  10. PU.1 Suppresses Th2 Cytokine Expression via Silencing of GATA3 (show GATA3 ELISA Kits) Transcription in Dendritic Cells

Human Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 (SPI1) interaction partners

  1. expression of an essential mediator of neutrophil terminal differentiation, the ets transcription factor (show FEV ELISA Kits) PU.1, was significantly decreased in Hbb (show HBB ELISA Kits)(th3/+) neutrophils in beta-thalassemia

  2. RUNX1 (show RUNX1 ELISA Kits) overexpression induced partial DNA demethylation at SPI1 proximal promoter.

  3. This study demonstrated the novel role of PU.1 in the immune response to A. fumigatus through upregulation of Dectin-1 (show CLEC7A ELISA Kits) expression and its translocation to the nucleus in A. fumigatus-stimulated THP-1 (show GLI2 ELISA Kits) cells.

  4. PU.1 is an important modulator of VDR (show CYP27B1 ELISA Kits) signaling in monocytes.

  5. Forced FOG1 protein expression in K562 erythroleukemia cells induced the expression of SLC4A1 (show SLC4A1 ELISA Kits) protein, but repressed that of transcription factor PU.1.

  6. Moreover, the expression of a cell proliferation marker Ki67 (show MKI67 ELISA Kits) was significantly decreased in tumors from the mice not taking doxycycline, compared with that of tumors from the mice continuously taking doxycycline. The present data strongly suggest that PU.1 functions as a tumor suppressor of myeloma cells in vivo.

  7. we demonstrated that miR (show MLXIP ELISA Kits)-22 promoted monocyte/macrophage differentiation, and MECOM (EVI1 (show MECOM ELISA Kits)) mRNA is a direct target of miR (show MLXIP ELISA Kits)-22 and MECOM (EVI1 (show MECOM ELISA Kits)) functions as a negative regulator in the differentiation.The miR (show MLXIP ELISA Kits)-22-mediated MECOM (show MECOM ELISA Kits) degradation increased c-Jun (show JUN ELISA Kits) but decreased GATA2 (show GATA2 ELISA Kits) expression, which results in increased interaction between c-Jun (show JUN ELISA Kits) and PU.1

  8. we conclude that PU.1 transactivates the pIII through direct binding to Ets (show ETS1 ELISA Kits)-motifs in the promoter in pDCs

  9. Our results suggest the existence of a Vav1 (show VAV1 ELISA Kits)/PU.1/miR (show MLXIP ELISA Kits)-142-3p network that supports all-trans retinoic acid -induced differentiation in acute promyelocytic leukemia (show PML ELISA Kits) -derived cells

  10. Our data suggest that E2A (show TCF3 ELISA Kits) antagonism of PU.1 activity contributes to its ability to commit multipotential hematopoietic progenitors to the lymphoid lineages.

Pig (Porcine) Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 (SPI1) interaction partners

Zebrafish Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 (SPI1) interaction partners

  1. The vertical and paralleled Pu.1/Spi-b (show SPIB ELISA Kits) regulatory networks control the development of rostral blood island and ventral wall of dorsal aorta-borne macrophages by regulating Irf8 (show IRF8 ELISA Kits).

  2. eaf1 has a role in suppressing foxo3b expression to modulate transcriptional activity of gata1 (show GATA1 ELISA Kits) and spi1 in primitive hematopoiesis

  3. Our results indicate that Kzp (show ANPEP ELISA Kits) is a critical transcriptional factor for the expression of gata2 and pu.1 to modulate primitive hematopoiesis.

  4. Runx1 (show RUNX1 ELISA Kits) is induced by high Pu.1 level and in turn transrepresses pu.1 expression, thus constituting a negative feedback loop that fashions a favorable Pu.1 level required for balanced fate commitment to neutrophils versus macrophages.

  5. The authors show that tif1gamma (show TRIM33 ELISA Kits) modulates the erythroid versus myeloid fate outcomes from HSCs by differentially controlling the levels of gata1 (show GATA1 ELISA Kits) and pu.1.

  6. found a gene group downregulated on spi1 knockdown,containing all 5 previously identified Spi1-dependent genes as well as a large set of novel immune-related genes

  7. In zebrafish, spi1 marks a rostral population of LPM cells committed to a myeloid fate anatomically separated from and developmentally independent of erythroid commitment in the caudal (show CAD ELISA Kits) LPM.

Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 (SPI1) Antigen Profile

Antigen Summary

This gene encodes an ETS-domain transcription factor that activates gene expression during myeloid and B-lymphoid cell development. The nuclear protein binds to a purine-rich sequence known as the PU-box found near the promoters of target genes, and regulates their expression in coordination with other transcription factors and cofactors. The protein can also regulate alternative splicing of target genes. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 (SPI1)

  • serine (or cysteine) peptidase inhibitor, clade A, member 3D, pseudogene (Serpina3d-ps) Elisa Kit
  • Serine protease inhibitor (LOC299282) Elisa Kit
  • spleen focus forming virus (SFFV) proviral integration oncogene (SPI1) Elisa Kit
  • spleen focus forming virus (SFFV) proviral integration oncogene (Spi1) Elisa Kit
  • spleen focus forming virus (SFFV) proviral integration oncogene spi1 (SPI1) Elisa Kit
  • spleen focus forming virus (SFFV) proviral integration oncogene spi1b (spi1b) Elisa Kit
  • 2B1 Elisa Kit
  • Ab1-021 Elisa Kit
  • cb1086 Elisa Kit
  • CPi-23 Elisa Kit
  • Dis-1 Elisa Kit
  • Dis1 Elisa Kit
  • Gm5657 Elisa Kit
  • OF Elisa Kit
  • pu.1 Elisa Kit
  • pu1 Elisa Kit
  • Serpina3d Elisa Kit
  • Serpina3l Elisa Kit
  • Sfpi-1 Elisa Kit
  • sfpi1 Elisa Kit
  • si:by184l24.2 Elisa Kit
  • Spi-1 Elisa Kit
  • SPI-A Elisa Kit
  • SPI1 Elisa Kit
  • Spin1 Elisa Kit
  • Spin2a Elisa Kit
  • Tcfpu1 Elisa Kit
  • Tfpu.1 Elisa Kit

Protein level used designations for SPI1

SPI-1 , SPI-2.1 , contrapsin-like protease inhibitor 3 , contrapsin-like protease inhibitor-related protein , liver regeneration protein lrryan , serine protease inhibitor 1 , serine protease inhibitor 2.1 , serine protease inhibitor 2a , serine protease inhibitor A3L , serpin A3L , 31 kDa transforming protein , 31 kDa-transforming protein , SPI-1 proto-oncogene , hematopoietic transcription factor PU.1 , spleen focus forming virus (SFFV) proviral integration oncogene spi1 , transcription factor PU.1 , SFFV proviral integration 1 protein , SFFV proviral integration 1 , spleen focus forming virus proviral integration oncogene spi1 , Spi-1/PU.1 transcription factor , transcription factor spi1

GENE ID SPECIES
435318 Mus musculus
299282 Rattus norvegicus
6688 Homo sapiens
20375 Mus musculus
366126 Rattus norvegicus
395879 Gallus gallus
611255 Canis lupus familiaris
414912 Sus scrofa
507100 Bos taurus
30117 Danio rerio
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