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Browse our COMT (COMT) ELISA Kits

Full name:
Catechol-O-Methyltransferase ELISA Kits (COMT)
On are 34 Catechol-O-Methyltransferase (COMT) ELISA Kits from 9 different suppliers available. Additionally we are shipping COMT Antibodies (189) and COMT Proteins (29) and many more products for this protein. A total of 264 COMT products are currently listed.
comt, Comt1, D16Wsu103e, D330014B15Rik, mb-comt, MGC154444, s-comt

Top referenced COMT ELISA Kits

  1. Human COMT Primary Antibody for ELISA - ABIN481734 : Karpeta, Warzecha, Jerzak, Ptak, Gregoraszczuk: Activation of the enzymes of phase I (CYP2B1/2) and phase II (SULT1A and COMT) metabolism by 2,2',4,4'-tetrabromodiphenyl ether (BDE47) in the pig ovary. in Reproductive toxicology (Elmsford, N.Y.) 2012 (PubMed)

More ELISA Kits for COMT Interaction Partners

Horse (Equine) Catechol-O-Methyltransferase (COMT) interaction partners

  1. An analysis of polymorphisms of the COMT gene as a preliminary step in evaluating the role of the gene in behavior is reported.

Human Catechol-O-Methyltransferase (COMT) interaction partners

  1. The study suggested COMT Val158Met gene polymorphism may not be an independent risk factor for Tardive dyskinesia susceptibility, especially in East Asians (meta-analysis).

  2. Our results suggest a moderating effect of the COMT Val158Met polymorphism on the association between cognitive functioning and White Matter microstructure.

  3. COMT and age may interact to shape daily affective experience across the life span; results suggest that Met (vs. Val) carriers experience lower levels of affective well-being in younger but not in older ages; findings suggest that age-related improvements in emotional functioning may offset genetic vulnerabilities to negative affective experience

  4. Patients with bulimia nervosa and binge-eating disorder presented higher S-COMT activity in erythrocytes, which is in agreement with previous studies on the literature addressing the high-activity COMT allele, Val158, as risk factor for eating disorders.

  5. the association between MTHFR (show MTHFR ELISA Kits) c.C677T (p.A222V) and COMT c.G472A (p.V158M) polymorphisms and their synergism with respect to bipolar I disorder (BID (show BID ELISA Kits)). Our findings indicate the lower activity allele of MTHFR (show MTHFR ELISA Kits) (677T) increased the risk of BID (show BID ELISA Kits). In addition, the concomitant presence of the MTHFR (show MTHFR ELISA Kits) 677T allele with the COMT 472G allele associated with increased susceptibility to BID (show BID ELISA Kits) in our population

  6. Women with COMT Val/Val genotype are at high risk of developing multiple uterine fibroids either positive or negative for MED12 (show MED12 ELISA Kits) exon 2 mutations.

  7. we genotyped five hormone-related genes: estrogen receptor-alpha (ESR1 (show ESR1 ELISA Kits)), aromatase (CYP19 (show CYP19A1 ELISA Kits)), catechol-O-methyl transferase (COMT), sex hormone-binding globulin (SHBG (show SHBG ELISA Kits))and glutathione S-transferase (show GSTa2 ELISA Kits) (GSTP1 (show GSTP1 ELISA Kits)). Our data demonstrate that these ESR1 (show ESR1 ELISA Kits), GSTP1 (show GSTP1 ELISA Kits), and CYP19 (show CYP19A1 ELISA Kits) polymorphisms are associated with risk of BC, and the risk haplotype TGGGGTC could help to identify populations with high susceptibility to BC in Chinese women.

  8. No significant differences were found in COMT genotypes, allele frequencies, or haplotypes among migraine patient groups and controls.

  9. No association of functional polymorphisms in the estrogen metabolism genes COMT with menstrual migraine.

  10. genetic association studies in a population in Denmark: Data suggest that, compared to non-carriers of the COMT SNP rs4680 A allele, carriers/heterozygotes (AA/AG) report higher bone pressure pain tolerance threshold (i.e., less pain) by up to 23.8%.

Mouse (Murine) Catechol-O-Methyltransferase (COMT) interaction partners

  1. Miroestrol restored uterine COMT expression in beta-naphthoflavone-treated mice.

  2. This study report that genetically driven reduction in COMT enzyme activity increased cortical thickness in the prefrontal cortex (PFC (show CFP ELISA Kits)) and postero-parieto-temporal cortex of male, but not female adult mice.

  3. COMT expression in the hippocampus was significantly reduced by high E2 replacement, implying increased catecholamine levels in the hippocampus of high E2 mice.

  4. COMT overexpressing mice display an increase in dopamine release capacity in the striatum, suggesting increased COMT activity may affect dopamine signaling by enhancing synaptic clearance in the cortex and changes in striatal presynaptic dopamine function

  5. These data confirm at the level of mouse working memory and human working memory-associated physiology a genetic interaction between COMT and DTNBP1 (show DTNBP1 ELISA Kits).

  6. The results of this study suggest that individual differences in COMT activity do not affect primary reinforcing effects of cocaine in mice.

  7. Inhibition of COMT via serotonin binding contributes to pain hypersensitivity.

  8. COMT knockout mice were more impulsive compared with wild-type littermates.

  9. Data show that in male catechol-O-methyltransferase COMT(-/-)-mice, the total number of T-, and B-lymphocytes from spleen increased but the T-cell proliferative response decreased.

  10. decreased COMT activity was associated with some changes in feeding microstructure in rats and mice

COMT Antigen Profile

Antigen Summary

Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini. Several transcript variants are formed through the use of alternative translation initiation sites and promoters.

Alternative names and synonyms associated with COMT

  • catechol-O-methyltransferase (COMT) Elisa Kit
  • catechol-O-methyltransferase (comt) Elisa Kit
  • catechol-O-methyltransferase (comt.2) Elisa Kit
  • catechol-o-methyltransferase (Rv1703c) Elisa Kit
  • catechol-o-methyltransferase (Mb1729c) Elisa Kit
  • catechol O-methyltransferase-like (LOC100630273) Elisa Kit
  • catechol-O-methyltransferase (Comt) Elisa Kit
  • comt Elisa Kit
  • Comt1 Elisa Kit
  • D16Wsu103e Elisa Kit
  • D330014B15Rik Elisa Kit
  • mb-comt Elisa Kit
  • MGC154444 Elisa Kit
  • s-comt Elisa Kit

Protein level used designations for COMT

catechol-O-methyltransferase , catechol-o-methyltransferase , catechol O-methyltransferase, soluble form , catechol O-methyltransferase, membrane-bound form , catechol O-methyltransferase , O-methyltransferase , catechol-O-methyltransferase 1 , catecholamine-O-methyltransferase

416783 Gallus gallus
458655 Pan troglodytes
549111 Xenopus (Silurana) tropicalis
549911 Xenopus (Silurana) tropicalis
779254 Xenopus laevis
885066 Mycobacterium tuberculosis H37Rv
1092683 Mycobacterium bovis AF2122/97
100033869 Equus caballus
100146509 Equus caballus
100630273 Equus caballus
1312 Homo sapiens
445450 Canis lupus familiaris
12846 Mus musculus
24267 Rattus norvegicus
618278 Bos taurus
100155530 Sus scrofa
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