Browse our anti-CYP1A1 (CYP1A1) Antibodies

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anti-Cytochrome P450, Family 1, Subfamily A, Polypeptide 1 Antibodies (CYP1A1)
On are 128 Cytochrome P450, Family 1, Subfamily A, Polypeptide 1 (CYP1A1) Antibodies from 22 different suppliers available. Additionally we are shipping CYP1A1 Kits (33) and CYP1A1 Proteins (10) and many more products for this protein. A total of 182 CYP1A1 products are currently listed.
AHH, AHRR, CP11, CYP1, CYP1A1, Cyp1a2, Cyp45c, Cypc45c, CYPIA1, P-450MC, P1-450, P450-1, P450-C, P450DX
list all antibodies Gene Name GeneID UniProt
CYP1A1 1543 P04798
CYP1A1 24296 P00185
CYP1A1 13076 P00184

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Most Popular Reactivities for anti-CYP1A1 (CYP1A1) Antibodies

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anti-Human CYP1A1 Antibodies:

anti-Rat (Rattus) CYP1A1 Antibodies:

anti-Mouse (Murine) CYP1A1 Antibodies:

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Top referenced anti-CYP1A1 Antibodies

  1. Human Monoclonal CYP1A1 Primary Antibody for WB - ABIN1882231 : Pande, Amos, Eng, Frazier: Interactions between cigarette smoking and selected polymorphisms in xenobiotic metabolizing enzymes in risk for colorectal cancer: A case-only analysis. in Molecular carcinogenesis 2010 (PubMed)
    Show all 5 references for 1882231

  2. Human Monoclonal CYP1A1 Primary Antibody for WB - ABIN1882232 : Sabitha, Reddy, Jamil: Smoking related risk involved in individuals carrying genetic variants of CYP1A1 gene in head and neck cancer. in Cancer epidemiology 2010 (PubMed)
    Show all 5 references for 1882232

  3. Human Monoclonal CYP1A1 Primary Antibody for IHC, ELISA - ABIN969511 : Canova, Hashibe, Simonato, Nelis, Metspalu, Lagiou, Trichopoulos, Ahrens, Pigeot, Merletti, Richiardi, Talamini, Barzan, Macfarlane, Macfarlane, Holcátová, Bencko, Benhamou, Bouchardy, Kjaerheim et al.: Genetic associations of 115 polymorphisms with cancers of the upper aerodigestive tract across 10 European countries: the ARCAGE project. ... in Cancer research 2009 (PubMed)
    Show all 2 references for 969511

  4. Human Polyclonal CYP1A1 Primary Antibody for EIA, WB - ABIN360414 : Delpisheh, Brabin, Topping, Reyad, Tang, Brabin: A case-control study of CYP1A1, GSTT1 and GSTM1 gene polymorphisms, pregnancy smoking and fetal growth restriction. in European journal of obstetrics, gynecology, and reproductive biology 2009 (PubMed)
    Show all 2 references for 360414

  5. Human Polyclonal CYP1A1 Primary Antibody for EIA, IHC (p) - ABIN360413 : Zhuo, Wang, Zhuo, Zhu, Wang, Zhu, Li, Chen: CYP1A1 and GSTM1 polymorphisms and oral cancer risk: association studies via evidence-based meta-analyses. in Cancer investigation 2009 (PubMed)
    Show all 2 references for 360413

  6. Cow (Bovine) Polyclonal CYP1A1 Primary Antibody for IHC, WB - ABIN2776792 : Ikeda, Sasazuki, Natsukawa, Shaura, Koizumi, Kasuga, Ohnami, Sakamoto, Yoshida, Iwasaki, Tsugane: Screening of 214 single nucleotide polymorphisms in 44 candidate cancer susceptibility genes: a case-control study on gastric and colorectal cancers in the Japanese population. in The American journal of gastroenterology 2008 (PubMed)

  7. Human Polyclonal CYP1A1 Primary Antibody for IHC (p), WB - ABIN392526 : Foster, Jacobsen, Kenna, Schulz-Utermoehl, Morikawa, Salmu, Wilson: Differential effect of troglitazone on the human bile acid transporters, MRP2 and BSEP, in the PXB hepatic chimeric mouse. in Toxicologic pathology 2012 (PubMed)

  8. Rat (Rattus) Polyclonal CYP1A1 Primary Antibody for ELISA, WB - ABIN4302060 : Sulem, Gudbjartsson, Geller, Prokopenko, Feenstra, Aben, Franke, den Heijer, Kovacs, Stumvoll, Mägi, Yanek, Becker, Boyd, Stacey, Walters, Jonasdottir, Thorleifsson, Holm, Gudjonsson, Rafnar et al.: Sequence variants at CYP1A1-CYP1A2 and AHR associate with coffee consumption. ... in Human molecular genetics 2011 (PubMed)

More Antibodies against CYP1A1 Interaction Partners

Pig (Porcine) Cytochrome P450, Family 1, Subfamily A, Polypeptide 1 (CYP1A1) interaction partners

  1. Significant CYP1A1 expression increases over control animals was observed in ileum tissue in swine exposed to a single dose of 10 mgkg-bw-1 PAHs

  2. There was no association between CYP1A1 C genotype and survival in the overall study population

  3. The effect of human chorionic gonadotropin on the activities of cytochrome P-450 (show CYP Antibodies) CYP1A1, cytochrome P-450 (show CYP Antibodies) CYP2B1 (show Cyp2b1 Antibodies) and methoxyresorufin O-demethylase (show MBD2 Antibodies) (MROD) was studied in intact male pigs of 2 breeds.[CYP2B1 (show Cyp2b1 Antibodies); MROD]

  4. This study demonstrated for the first time that the serum testosterone level is one of the physiological factors which regulate constitutive expression of hepatic CYP1A1 and CYP1A2 (show CYP1A2 Antibodies) in pigs.

  5. The findings demonstrate a gender-related difference in the constitutive expression of hepatic CYP1A1 in Meishan pigs and further indicate that testosterone down-regulates the constitutive gene expression of the enzyme.

  6. Distinct subtypes of urinary bladder epithelial cells with inducible and non-inducible cytochrome P-450 (show CYP Antibodies) CYP1A1 are reported.

  7. Effect of beta-napthoflavone on AHR (show AHR Antibodies)-related gene, CYP1A1, in the pig is reported.

Human Cytochrome P450, Family 1, Subfamily A, Polypeptide 1 (CYP1A1) interaction partners

  1. the CYP1A1 polymorphisms are potential risk factors for digestive tract cancer.

  2. was observed that the variant genotypes of GSTM1 (show GSTM1 Antibodies), GSTT1 (show GSTT1 Antibodies), GSTP1 (show GSTP1 Antibodies) and CYP1A1 did not significantly increase the risk of cervical cancer (CC), however, statistically significant increased risk was observed for women who used wood for cooking and had GSTM1 (show GSTM1 Antibodies) (null) genotype.

  3. CYP1A1*2A was not associated with Colorectal Cancer(CRC (show CALR Antibodies))development (OR = 1.566; 95% confidence interval [CI] = 0.90-2.73; p = 0.12); C allele-carrying individuals who had smoked within the past 5 years had a significant risk of CRC (show CALR Antibodies) (OR = 2.28; 95% CI = 1.07-4.86; p = 0.043).

  4. CYP1A1 polymorphisms were not associated with sporadic colorectal neoplasms.

  5. Allele frequency of the CYP1A1 3801T>C polymorphism does not correlate with semen production as determined by sperm counts or sperm function as determined by fertilization rates with ICSI.

  6. data indicate that CYP1A1 I462V allele confers the least carcinogen-associated genotoxicity, compared to CYP1A1; however, results vary depending on the chemical carcinogen and the genotoxic endpoint

  7. By sequencing Apc (show APC Antibodies) and Ctnnb1 (show CTNNB1 Antibodies) genes, we found that most PhIP (show PHIP Antibodies)-induced small intestinal tumors in obese mice carried only a single heterozygous mutation in Apc (show APC Antibodies) . Our findings demonstrate that PhIP (show PHIP Antibodies)-induced small intestinal carcinogenesis in hCYP1A-db/db (show LEPR Antibodies) mice is promoted by obesity and involves Apc (show APC Antibodies) mutation and inactivation by DNA hypermethylation

  8. The rapid activation of the Ah receptor (show AHR Antibodies) and CYP1A1 protein expression by higher chlorinated polychlorinated naphthalene point to their toxicity; however, it is not sufficient for potential carcinogenicity.

  9. The polymorphism of CYP1A1*4 is associated with esophageal squamous cell carcinoma risk.

  10. Our results showed that 3 single nucleotide polymorphisms of ACE rs4340, IL-6 rs1800795, and NOS3 rs1799983 were significantly associated with the risks of mycoplasma pneumoniae pneumonia (MPP), while no differences were observed in genotype frequencies of GSTM1 and CYP1A1. The combinations of ACE/NOS3/CYP1A1 and ACE /NOS3 contribute to the genetic susceptibility of MPP in Chinese children.

Mouse (Murine) Cytochrome P450, Family 1, Subfamily A, Polypeptide 1 (CYP1A1) interaction partners

  1. Miroestrol suppressed beta-naphthoflavone increases in CYP1A1.

  2. Taken together, CAPE decreases 3-MC-mediated CYP1A1 expression, and this inhibitory response is associated with inhibition of AhR (show AHR Antibodies) and HIF-1alpha (show HIF1A Antibodies) induction.

  3. Our results support the hypothesis that CYP1A1 protects against hyperoxic lung injury by decreasing oxidative stress.

  4. CYP1A1 contributes to nitric oxide bioavailability and blood pressure regulation mediated by dietary omega-3 polyunsaturated fatty acids.

  5. Aryl hydrocarbon receptor (show AHR Antibodies) mediated induction of hepatic CYP1A1/1A2 is dependent on the presence of ctnnb1 (show CTNNB1 Antibodies).

  6. Suggest that CYP1A induction by coplanar polychlorinated/brominated biphenyls depends on AhR (show AHR Antibodies) transcriptional activity and not on AhR (show AHR Antibodies) expression.

  7. Identify hepatic proteins necessary for the AHR (show AHR Antibodies)-dependent induction of CYP1A1 by 2,3,7,8-tetrachlorodibenzo-p-dioxin.

  8. In livers of HRN mice Cyp1a1, cytochrome b5 (show CYB5A Antibodies) and mEH (show EPHX1 Antibodies) can effectively activate BaP (show PHB2 Antibodies) to DNA binding species, even in the presence of very low amounts of P450 (show POR Antibodies) oxidoreductase (show HSD17B6 Antibodies).

  9. Reactive oxygen species production contributes to benzo[a]pyrene (BaP (show PHB2 Antibodies))-exacerbated atherosclerosis and CYP1A1 plays a protective role against oral BaP (show PHB2 Antibodies) toxicity in aorta

  10. harmine and harmaline are promising candidate to inhibit TCDD-mediated induction of Cyp1a1 in mice hepatic and extrahepatic tissues

Rabbit Cytochrome P450, Family 1, Subfamily A, Polypeptide 1 (CYP1A1) interaction partners

  1. CYP1A1 and CYP1A2 (show CYP1A2 Antibodies) localization into different lipid microdomains is governed by their N-terminal and internal protein regions

CYP1A1 Antigen Profile

Antigen Summary

This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown\; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15.

Alternative names and synonyms associated with CYP1A1

  • cytochrome P450, family 1, subfamily A, polypeptide 1 (CYP1A1) antibody
  • cytochrome P450 1A1 (CYPIA1) antibody
  • cytochrome P450 1A1 (CpipJ_CPIJ010542) antibody
  • cytochrome P450 1A1 (cyp1a1) antibody
  • cytochrome P450 1A1 (CYP1A1) antibody
  • cytochrome P450, family 1, subfamily a, polypeptide 1 (Cyp1a1) antibody
  • cytochrome P4501A1 (CYP1A1) antibody
  • polycyclic hydrocarbon-inducible cytochrome P450c (LOC100328613) antibody
  • AHH antibody
  • AHRR antibody
  • CP11 antibody
  • CYP1 antibody
  • CYP1A1 antibody
  • Cyp1a2 antibody
  • Cyp45c antibody
  • Cypc45c antibody
  • CYPIA1 antibody
  • P-450MC antibody
  • P1-450 antibody
  • P450-1 antibody
  • P450-C antibody
  • P450DX antibody

Protein level used designations for CYP1A1

cytochrome P450 1A1 , CYPIA1 , cytochrome P450 CYP1A1 , aryl hydrocarbon hydroxylase , cytochrome P1-450, dioxin-inducible , cytochrome P450 form 6 , cytochrome P450, subfamily I (aromatic compound-inducible), polypeptide 1 , cytochrome P450-C , cytochrome P450-P1 , flavoprotein-linked monooxygenase , xenobiotic monooxygenase , P450MT2 , P450form6 , cytochrome P1-450 , cytochrome P450 subfamily I (aromatic compound-inducible) member A1 (C6 form c) (C6 form c) , cytochrome P450, 1a1 , cytochrome P450, subfamily I (aromatic compound-inducible), member A1 (C6, form c) (C6, form c) , cytochrome P450MT2 , dioxin-inducible , microsomal monooxygenase , aromatic compound inducible , cytochrome P450 family 1 subfamily a polypeptide 2 , cytochrome P450 subfamily I, polypeptide 1 , cytochrome P450, 1a1, aromatic compound inducible , P-450 PHPAH1 , P450 LM6 , P450 isozyme 6 , cytochrome P-450 PHPAH1 , cytochrome P450 LM6 , cytochrome P450 isozyme 6

678694 Macaca mulatta
704920 Macaca mulatta
6043063 Culex quinquefasciatus
100020715 Monodelphis domestica
100062285 Equus caballus
100145341 Xenopus (Silurana) tropicalis
403103 Sus scrofa
554347 Felis catus
1543 Homo sapiens
24296 Rattus norvegicus
13076 Mus musculus
100686778 Canis lupus familiaris
100135512 Cavia porcellus
100170113 Ovis aries
100328613 Oryctolagus cuniculus
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