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Browse our Ataxin 1 (ATXN1) ELISA Kits

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Ataxin 1 ELISA Kits (ATXN1)
On www.antibodies-online.com are 31 Ataxin 1 (ATXN1) ELISA Kits from 6 different suppliers available. Additionally we are shipping Ataxin 1 Antibodies (208) and Ataxin 1 Proteins (8) and many more products for this protein. A total of 259 Ataxin 1 products are currently listed.
Synonyms:
2900016G23Rik, ataxin 1b, Atx1, atxn1, C85907, CG4547, D6S504E, dAtx-1, dAtx1, Dmel\\CG4547, ENSMUSG00000074917, Gm10786, sca1
list all ELISA KIts Gene Name GeneID UniProt
ATXN1 6310 P54253
ATXN1 20238 P54254
ATXN1 25049 Q63540

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More ELISA Kits for Ataxin 1 Interaction Partners

Fruit Fly (Drosophila melanogaster) Ataxin 1 (ATXN1) interaction partners

  1. Ataxin-1 induces intranuclear accumulation of dAtx2/hAtaxin-2 in both Drosophila and SCA1 postmortem neurons

  2. mutant ataxin-1 and huntingtin (show HTT ELISA Kits) induce developmental and late-onset neuronal pathologies in Drosophila models

Human Ataxin 1 (ATXN1) interaction partners

  1. SCA1 phenotypes could be reversed by partial suppression of human mutant ATXN1 mRNA by rAAV.miS1 when delivered after symptom onset in mice.

  2. SCA1 relative frequency in Poland shows the highest value compared with the data from other countries worldwide in patient with Spinocerebellar ataxias

  3. Studied Ataxin-1 using molecular modeling to investigate the protein-protein interactions contributing to the AXH domain dimer stability.

  4. Data indicate that in spinocerebellar ataxia (show USP14 ELISA Kits) type 1 patients the spinocerebellar ataxia type 1 protein trinucleotide repeat expansion (CAG)n was great than 39, comparing with normal 6-38.

  5. This study reports the results of molecular dynamics simulations of AXH monomer of Ataxin-1.

  6. Systematic replacement of each lysine residue in the AXH domain revealed that the lysine at 589 (K589) of ATXN1 is essential for its ubiquitylation by UbcH6 (show UBE2E1 ELISA Kits).

  7. Results show that two SNPs in ATXN1 gene have a founder effect of the same repeat carrying allele as in the general Indian population suggesting that that Spinocerebellar ataxia (show USP14 ELISA Kits) type 1 disease onset is significantly delayed when transmission is maternal.

  8. this work provides the structural and molecular basis of the interaction between RBM17 (show RBM17 ELISA Kits) and the phosphorylated form of ATXN1.

  9. Partner recognition of the AXH domain of the transcriptional co-regulator ataxin-1 is fine-tuned by a subtle balance between self- and hetero-associations.

  10. We measured cerebellar neurochemical alterations in a knock-in mouse model of spinocerebellar ataxia (show USP14 ELISA Kits) type 1, a hereditary movement disorder, using ultra-high field magnetic resonance spectroscopy (MRS).

Mouse (Murine) Ataxin 1 (ATXN1) interaction partners

  1. Maternal diabetes induced caspase 3 (show CASP3 ELISA Kits)-dependent apoptosis in Sca1(+) cardiac progenitor cells derived from embryonic day 17.5 (E17.5). Both maternal diabetes and high glucose in vitro activated the pro-apoptotic transcription factor, Forkhead O 3a (FoxO3a (show FOXO3 ELISA Kits)) via dephosphorylation at threonine 32 (Thr (show TRH ELISA Kits)-32) residue.

  2. Data establish a novel role for ATXN1 in the hippocampus as an intrinsic regulator of precursor cell proliferation, and suggest a mechanism by which polyQ expansion and loss of ATXN1 affect hippocampal function, potentially contributing to cognitive deficits and depression

  3. The results of this study found that upregulation of cholecystokinin (Cck (show CCK ELISA Kits)) and subsequent interaction with the Cck1 (show CCL28 ELISA Kits) receptor likely underlies the lack of progressive Purkinje cell pathology in Pcp2-ATXN1[30Q]D776 mice.

  4. Mutant ATXN1 forms oligomers whose levels correlate with disease progression in the Atxn1154Q/+ mice.

  5. The study showed that Sca1(+)Lin(-) bone marrow contains an endodermal precursor population of cells that differentiates into hepatocytes.

  6. HMGB1 (show HMGB1 ELISA Kits) facilitates repair of mitochondrial DNA damage of mutant ataxin-1 knock-in mice.

  7. The RNA-binding protein PUMILIO1 (PUM1 (show PUM1 ELISA Kits)) not only directly regulates ATAXIN1 but also plays an unexpectedly important role in neuronal function. Loss of Pum1 (show PUM1 ELISA Kits) caused progressive motor dysfunction and SCA1-like neurodegeneration with motor impairment, primarily by increasing Ataxin1 levels.

  8. study found a new function of ataxin-1: the modulation of Pp2a activity and the regulation of its holoenzyme composition, with the polyglutamine mutation within Atxn1 altering this function in the spinocerebellar ataxia (show USP14 ELISA Kits) type 1 mouse cerebellum before disease onset

  9. Delivery of either ataxin-1-like viral vectors to Spinocerebellar Ataxia (show USP14 ELISA Kits) Type 1 mice cerebella resulted in widespread cerebellar Purkinje cell transduction

  10. downregulation of several components of the RAS-MAPK (show MAPK1 ELISA Kits)-MSK1 (show RPS6KA5 ELISA Kits) pathway decreases ATXN1 levels and suppresses neurodegeneration in mice

Ataxin 1 (ATXN1) Antigen Profile

Antigen Summary

The autosomal dominant cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum, brain stem and spinal cord. Clinically, ADCA has been divided into three groups: ADCA types I-III. ADCAI is genetically heterogeneous, with five genetic loci, designated spinocerebellar ataxia (SCA) 1, 2, 3, 4 and 6, being assigned to five different chromosomes. ADCAII, which always presents with retinal degeneration (SCA7), and ADCAIII often referred to as the `pure' cerebellar syndrome (SCA5), are most likely homogeneous disorders. Several SCA genes have been cloned and shown to contain CAG repeats in their coding regions. ADCA is caused by the expansion of the CAG repeats, producing an elongated polyglutamine tract in the corresponding protein. The expanded repeats are variable in size and unstable, usually increasing in size when transmitted to successive generations. The function of the ataxins is not known. This locus has been mapped to chromosome 6, and it has been determined that the diseased allele contains 41-81 CAG repeats, compared to 6-39 in the normal allele, and is associated with spinocerebellar ataxia type 1 (SCA1). At least two transcript variants encoding the same protein have been found for this gene.

Alternative names and synonyms associated with Ataxin 1 (ATXN1)

  • ataxin 1 (ATXN1) Elisa Kit
  • ataxin 1b (atxn1b) Elisa Kit
  • Ataxin 1 (Atx-1) Elisa Kit
  • ataxin 1 (Atxn1) Elisa Kit
  • ataxin 1-like (ATXN1L) Elisa Kit
  • 2900016G23Rik Elisa Kit
  • ataxin 1b Elisa Kit
  • Atx1 Elisa Kit
  • atxn1 Elisa Kit
  • C85907 Elisa Kit
  • CG4547 Elisa Kit
  • D6S504E Elisa Kit
  • dAtx-1 Elisa Kit
  • dAtx1 Elisa Kit
  • Dmel\\CG4547 Elisa Kit
  • ENSMUSG00000074917 Elisa Kit
  • Gm10786 Elisa Kit
  • sca1 Elisa Kit

Protein level used designations for Ataxin 1 (ATXN1) ELISA Kits

ataxin 1 , spinocerebellar ataxia type 1 , Ataxin1 , Atx-1-PB , CG4547-PB , ataxin-1 , ataxin-1-like , spinocerebellar ataxia type 1 protein , spinocerebellar ataxia 1 homolog , spinocerebellar ataxia 1 , spinocerebellar ataxia type 1 protein homolog , spinocerebellar ataxia type 1 protien

GENE ID SPECIES
100065748 Equus caballus
493678 Felis catus
565841 Danio rerio
747421 Pan troglodytes
31624 Drosophila melanogaster
100025666 Monodelphis domestica
100402564 Callithrix jacchus
100437511 Pongo abelii
100467930 Ailuropoda melanoleuca
100588152 Nomascus leucogenys
6310 Homo sapiens
20238 Mus musculus
25049 Rattus norvegicus
488232 Canis lupus familiaris
100154571 Sus scrofa
616399 Bos taurus
100719683 Cavia porcellus
420843 Gallus gallus
101113284 Ovis aries
489725 Canis lupus familiaris
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