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c-mos (show MOS ELISA Kits) mRNA localizes with Zorba around the animal pole in the zebrafish oocyte suggesting that the animal cortex is the central core of oocyte maturation in zebrafish.
CPEB1 regulation of MMP9 (show MMP9 ELISA Kits) mRNA expression mediates metastasis of breast cancer cells
The host RNA-binding protein (show PTBP1 ELISA Kits) CPEB1 was highly induced after cytomegalovirus infection and ectopic expression of CPEB1 in non-infected cells recapitulated infection-related post-transcriptional changes. CPEB1 was also required for poly(A)-tail lengthening of viral RNAs important for productive infection.
Expression levels of CPEB4 and CPEB1 genes are correlated with overall survival in patients with glioma.
WEE1 (show WEE1 ELISA Kits) is regulated at the translational level by CPEB1 and miR (show MLXIP ELISA Kits)-15b in a coordinated and cell-cycle-dependent manner.
This mechanical catalysis makes possible a positive feedback loop that would help localize the formation of CPEB fibers to active synapse areas and mark those synapses for forming a long-term memory after the prion form is established. The functional role of the CPEB helical oligomers in this mechanism carries with it implications for targeting such species in neurodegenerative diseases.
Structural Analysis of the Pin1 (show PIN1 ELISA Kits)-CPEB1 interaction and its potential role in CPEB1 degradation has been described.
Identify a mechanism of VEGF overexpression in liver and mesentery that promotes pathologic, but not physiologic, angiogenesis, via sequential and nonredundant functions of CPEB1 and CPEB4.
CPEB1, 2, and 4, are essential to successful mitotic cell division.
Results suggest that CPEB1-mediated translational control is essential for the differentiation of GSCs.
CPEB accelerates deadenylation and decay of the c-myc mRNA by recruiting the Tob-Caf1 complex.
DAZL (show DAZL ELISA Kits) and CPEB1 regulate mRNA translation during oocyte maturation.
cytoplasmic-element-binding control of transforming growth factor beta-activated kinase 1 (show MAP3K7 ELISA Kits) mRNA translation mediates the inflammatory immune response
Myoepithelial cells prevent EMT (show ITK ELISA Kits) by influencing the polarity and proliferation of luminal epithelial cells in a mechanism that requires translational silencing of myoepithelial Twist1 (show TWIST1 ELISA Kits) by CPEB1.
Fmr1 (show FMR1 ELISA Kits)(-/y); Cpeb1(-/-) double-knockout mice displayed amelioration of biochemical, morphological, electrophysiological and behavioral phenotypes associated with fragile X (show FMR1 ELISA Kits) syndrome.
poly(A) polymerase (show PAPOLA ELISA Kits) Gld2 (show PAPD4 ELISA Kits), deadenylase PARN (show PARN ELISA Kits), and translation inhibitory factor neuroguidin (Ngd (show NGDN ELISA Kits)) are components of a dendritic CPEB-associated polyadenylation apparatus
CPEB-mediated zonal occludens-1 mRNA localization is essential for tight-junction assembly and mammary epithelial cell polarity
when the Cpeb1 knockout mice were fed a high-fat diet, their livers became insulin (show INS ELISA Kits)-resistant.Our results show that Cpeb1 regulated translation is a key process involved in insulin (show INS ELISA Kits) signaling
CPEB deficiency not only increases IL-6 (show IL6 ELISA Kits) production but also renders the cell incapable of a senescence-promoting response.
CPEB, localized in oocyte cytoplasm, was hyperphosphorylated during prophase/metaphase-I transition.
Aurora kinase A (show AURKA ELISA Kits) is unlikely to be involved in CPEB1 activating phosphorylation and cyclin B1 (show CCNB1 ELISA Kits) mRNA polyadenylation during meiotic maturation of porcine oocytes.
results suggest the involvement of mammalian CPEB1 in Cyclin B syntheses and meiotic resumption in mammalian oocytes
This gene encodes a member of the cytoplasmic polyadenylation element (CPE) binding protein family. This highly conserved protein binds to a specific RNA sequence called the CPE found in the 3' UTR of some mRNAs. Similar proteins in Xenopus and mouse function to induce cytoplasmic polyadenylation of dormant mRNAs with short polyA tails, resulting in their translation. Members of this protein family regulate translation of cyclin B1 during embryonic cell divisions. Multiple transcript variants encoding different isoforms have been found for this gene.
cytoplasmic polyadenylation element binding protein 1
, CPE-binding protein 1
, cytoplasmic polyadenylation element-binding protein 1
, cytoplasmic polyadenylation element-binding protein 1-like
, Orb/CPEB-related RNA-binding protein
, protein Zorba
, zebrafish orb-type a
, CPEB-related RNA binding protein