Browse our Gephyrin (GPHN) ELISA Kits

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Gephyrin ELISA Kits (GPHN)
On are 0 Gephyrin (GPHN) ELISA Kits from different suppliers available. Additionally we are shipping Gephyrin Antibodies (84) and Gephyrin Proteins (4) and many more products for this protein. A total of 94 Gephyrin products are currently listed.
5730552E08Rik, AI662856, BC027112, C230040D23, DKFZp459M0825, Geph, gpgb1, GPH, GPHN, GPHRYN, HKPX1
list all ELISA KIts Gene Name GeneID UniProt
Human GPHN GPHN 10243 Q9NQX3
Mouse GPHN GPHN 268566 Q8BUV3
Rat GPHN GPHN 64845 Q03555

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More ELISA Kits for Gephyrin Interaction Partners

Zebrafish Gephyrin (GPHN) interaction partners

  1. duplicated gephyrin genes mediate Moco biosynthesis and control postsynaptic clustering of glycine receptor (show GLRB ELISA Kits)

Human Gephyrin (GPHN) interaction partners

  1. these data reveal that IQSEC3 (show IQSEC3 ELISA Kits) acts together with gephyrin to regulate inhibitory synapse development.

  2. A missense mutation of gephyrin that was unable to synthesize MoCo and activate MoCo-dependent enzymes was identified.

  3. A yin-yang haplotype pattern encompassing gephyrin consists of 284 divergent nucleotide states and both variants vary drastically from their mutual ancestral haplotype, suggesting rapid evolution.

  4. The N-terminal region of GABRA3 (show GABRA3 ELISA Kits) and the GlyR beta subunit (show POLG ELISA Kits) occupies the same binding site of gephyrin.

  5. Results show that PKC-dependent phosphorylation of GAP43 (show GAP43 ELISA Kits) plays a critical role in regulating postsynaptic gephyrin aggregation in developing GABAergic synapses.

  6. Structural exonic microdeletions affecting the GPHN gene constitute a rare genetic risk factor for IGE and other neuropsychiatric disorders by an impairment of the GABAergic inhibitory synaptic transmission.

  7. The enhancement of Cb-induced gephyrin clustering by GTP (show AK3 ELISA Kits)-TC10 (show RHOQ ELISA Kits) does not depend on the guanine nucleotide exchange activity of Cb but involves an interaction that resembles reported interactions of other small GTPases with their effectors

  8. abnormal accumulations of gephyrin are highly correlated with the neuropathologic diagnosis of Alzheimer disease in 17 AD versus 14 control cases. Furthermore, gephyrin accumulations were specific for AD.

  9. Rare exonic deletions implicate the synaptic organizer Gephyrin (GPHN) in risk for autism, schizophrenia and seizures.

  10. Extracellular signal-regulated kinase and glycogen synthase kinase 3beta regulate gephyrin postsynaptic aggregation and GABAergic synaptic function in a calpain-dependent mechanism

Mouse (Murine) Gephyrin (GPHN) interaction partners

  1. Ablation of gephyrin result in the forebrain-specific loss of postsynaptic gamma2-GABAA (show GABRg1 ELISA Kits) receptors, reduces LTP (show SCP2 ELISA Kits) and network excitability in the dentate gyrus.

  2. adult mice lacking interleukin-1 receptor 1 (show IL1RL1 ELISA Kits) (IL-1R1) exhibit increased expression of both the excitatory scaffolding protein postsynaptic density-95 (PSD-95 (show DLGAP2 ELISA Kits)) and inhibitory scaffolding proteingephyrin, respectively, in the hippocampus.

  3. The results demonstrate that formation of GABAergic synapses containing a postsynaptic gephyrin scaffold is crucial for morphological differentiation, synaptic integration, and long-term survival of adult-born granule cells/

  4. Data suggest that KIF5 (show KIF5A ELISA Kits) regulates gephyrin sorting by a mechanism that involves GSK3 (show GSK3b ELISA Kits) activity.

  5. Pin1 (show PIN1 ELISA Kits)-dependent signaling represents a mechanism to modulate GABAergic transmission by regulating NL2 (show MMEL1 ELISA Kits)/gephyrin interaction.

  6. These results reveal a homeostatic mechanism through which activity regulates the dynamics and function of perisomatic inhibitory synapses, and they identify a CaMKII (show CAMK2G ELISA Kits)-dependent phosphorylation site on gephyrin.

  7. study reveals that palmitoylation of gephyrin by DHHC-12 contributes to dynamic and functional modulation of GABAergic synapses

  8. Within this network, collybistin (show Arhgef9 ELISA Kits) can adopt open/active and closed/inactive conformations to act as a switchable adaptor that links gephyrin to plasma membrane phosphoinositides.

  9. these findings suggest that gephyrin may be a key factor in BDNF (show BDNF ELISA Kits)-dependent GABAAR (show GABRG2 ELISA Kits) regulation in the amygdala.

  10. Data suggest that the loss of neurotransmitter receptor (show GRIN1 ELISA Kits) clustering at inhibitory synapses causes the early lethality of gephyrin deficient mice.

Gephyrin (GPHN) Antigen Profile

Antigen Summary

This gene encodes a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton via high affinity binding to a receptor subunit domain and tubulin dimers. In nonneuronal tissues, the encoded protein is also required for molybdenum cofactor biosynthesis. Mutations in this gene may be associated with the neurological condition hyperplexia and also lead to molybdenum cofactor deficiency. Numerous alternatively spliced transcript variants encoding different isoforms have been described\; however, the full-length nature of all transcript variants is not currently known.

Alternative names and synonyms associated with Gephyrin (GPHN)

  • gephyrin (GPHN) Elisa Kit
  • gephyrin a (gphna) Elisa Kit
  • gephyrin (PTRG_08978) Elisa Kit
  • gephyrin (VDBG_00775) Elisa Kit
  • gephyrin (Tsp_03043) Elisa Kit
  • gephyrin (gphn) Elisa Kit
  • gephyrin (Gphn) Elisa Kit
  • 5730552E08Rik Elisa Kit
  • AI662856 Elisa Kit
  • BC027112 Elisa Kit
  • C230040D23 Elisa Kit
  • DKFZp459M0825 Elisa Kit
  • Geph Elisa Kit
  • gpgb1 Elisa Kit
  • GPH Elisa Kit
  • GPHN Elisa Kit
  • GPHRYN Elisa Kit
  • HKPX1 Elisa Kit

Protein level used designations for Gephyrin (GPHN) ELISA Kits

gephyrin , gephyrin1 , gephyrin-like , gephyrin isoform , putative glycine receptor-tubulin linker protein

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