Browse our IL1RAPL1 Proteins (IL1RAPL1)

Full name:
Interleukin 1 Receptor Accessory Protein-Like 1 Proteins (IL1RAPL1)
On www.antibodies-online.com are 14 Interleukin 1 Receptor Accessory Protein-Like 1 (IL1RAPL1) Proteins from 5 different suppliers available. Additionally we are shipping IL1RAPL1 Antibodies (74) and IL1RAPL1 Kits (6) and many more products for this protein. A total of 98 IL1RAPL1 products are currently listed.
Synonyms:
6330532G10Rik, C030039N24, IL1R8, Il1rapl, MRX10, MRX21, MRX34, OPHN4, TIGIRR-2
list all proteins Gene Name GeneID UniProt
IL1RAPL1 11141 Q9NZN1
IL1RAPL1 331461  
IL1RAPL1 317553 P59824

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IL1RAPL1 Proteins (IL1RAPL1) by Origin

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Top referenced IL1RAPL1 Proteins

  1. Human IL1RAPL1 Protein expressed in Human Cells - ABIN2002254 : Yoshida, Mishina: Zebrafish orthologue of mental retardation protein IL1RAPL1 regulates presynaptic differentiation. in Molecular and cellular neurosciences 2008 (PubMed)
    Show all 4 references for 2002254

  2. Mouse (Murine) IL1RAPL1 Protein expressed in Human Cells - ABIN2008390 : Gambino, Pavlowsky, Béglé, Dupont, Bahi, Courjaret, Gardette, Hadjkacem, Skala, Poulain, Chelly, Vitale, Humeau: IL1-receptor accessory protein-like 1 (IL1RAPL1), a protein involved in cognitive functions, regulates N-type Ca2+-channel and neurite elongation. in Proceedings of the National Academy of Sciences of the United States of America 2007 (PubMed)
    Show all 3 references for 2008390

More Proteins for IL1RAPL1 Interaction Partners

Human Interleukin 1 Receptor Accessory Protein-Like 1 (IL1RAPL1) interaction partners

  1. Altered DNA methylation (show HELLS Proteins) in IL1RAPL1 involves in the etiology of Bipolar disorder and Major Depressive disorder .

  2. rs12007907 variant in IL1RAPL gene was negatively associated with asthma and IL-13 (show IL13 Proteins) production in Latin American children.

  3. Our study expands the molecular repertoire of IL1RAPL1 mutations in intellectual disability and points out the need of more accurate clinical descriptions to better define the related phenotype

  4. It was indicated that a defect in IL1RAPL1 that controls excitatory synapsis formation results in the excitation-inhibition balance affecting various cerebral functions.

  5. Novel IL1RAPL1 mutations associated with intellectual disability impair synaptogenesis.

  6. The interaction of the IL1RAPL1 family of proteins with PTPdelta and RhoGAP2 reveals a pathophysiological mechanism of cognitive impairment associated with a novel type of trans-synaptic signaling.

  7. The IL1RAPL1 gene is of interest as a candidate gene for autism spectrum disorder as mutations or deletions in the gene have previously been reported in individuals from families with ASD (show ARSD Proteins).

  8. Nearly all patients with deletions involving DAX1 (show NR0B1 Proteins), but not DMD (show DMD Proteins), had mental retardation if IL1RAPL1 was deleted. If ILIRAPLI & DMD (show DMD Proteins) were intact, the patients with DAX1 (show NR0B1 Proteins) deletions only rarely had normal development.

  9. Report confirms the role of the IL1RAPL1 gene in causing nonspecific mental retardation in males.

  10. DMD (show DMD Proteins) gene and its immediately distal neighbor, the 1.8 Mb IL1RAPL1 gene are abundantly expressed in normal brain but were dramatically underexpressed in every brain tumor cell line and xenograft.

Mouse (Murine) Interleukin 1 Receptor Accessory Protein-Like 1 (IL1RAPL1) interaction partners

  1. Here we show that the X-linked intellectual disability protein interleukin-1 receptor accessory protein like 1 (IL1RAPL1) regulates dendrite morphology of mice hippocampal neurons and induced pluripotent stem cell-derived neurons from a patient carrying a null mutation of IL1RAPL1 gene.

  2. These results thus reveal the decoding mechanism of splice-insert signaling codes for synaptic differentiation induced by trans-synaptic adhesion between PTPdelta and IL1RAPL1/IL-1RAcP (show IL1RAP Proteins).

  3. These results suggest that IL1RAPL1 ablation resulted in spine density decrease and affected not only learning but also behavioural flexibility, locomotor activity and anxiety.

  4. It was indicated that a defect in IL1RAPL1 that controls excitatory synapsis formation results in the excitation-inhibition balance affecting various cerebral functions.

  5. IL1RAPL1 associated with mental retardation and autism regulates the formation and stabilization of glutamatergic synapses of cortical neurons through RhoA (show RHOA Proteins) signaling pathway.

  6. the results of this study suggested that constitutive absence of Il1rapl1 disrupts this balance, possibly explaining the deficit in LTP (show SCP2 Proteins) induction in vivo and the behavioral deficits observed in KO mice.

  7. results suggest that IL1RAPL1 mediates synapse formation through trans-synaptic interaction with PTPdelta.

  8. Absence of IL1RAPL1 causes a transient disinhibition of deep cerebellar nuclei neurons between postnatal days 10 and 14.

IL1RAPL1 Protein Profile

Protein Summary

The protein encoded by this gene is a member of the interleukin 1 receptor family and is similar to the interleukin 1 accessory proteins. It is most closely related to interleukin 1 receptor accessory protein-like 2 (IL1RAPL2). This gene and IL1RAPL2 are located at a region on chromosome X that is associated with X-linked non-syndromic mental retardation. Deletions and mutations in this gene were found in patients with mental retardation. This gene is expressed at a high level in post-natal brain structures involved in the hippocampal memory system, which suggests a specialized role in the physiological processes underlying memory and learning abilities.

Alternative names and synonyms associated with IL1RAPL1

  • interleukin 1 receptor accessory protein-like 1 (IL1RAPL1)
  • interleukin 1 receptor accessory protein-like 1 (Il1rapl1)
  • 6330532G10Rik protein
  • C030039N24 protein
  • IL1R8 protein
  • Il1rapl protein
  • MRX10 protein
  • MRX21 protein
  • MRX34 protein
  • OPHN4 protein
  • TIGIRR-2 protein

Protein level used designations for IL1RAPL1

interleukin 1 receptor accessory protein-like 1 , IL-1-RAPL-1 , IL-1RAPL-1 , IL1RAPL-1 , X-linked interleukin-1 receptor accessory protein-like 1 , interleukin 1 receptor-8 , interleukin-1 receptor accessory protein-like 1 , mental retardation, X-linked 10 , oligophrenin-4 , three immunoglobulin domain-containing IL-1 receptor-related 2

GENE ID SPECIES
100546693 Meleagris gallopavo
11141 Homo sapiens
427993 Gallus gallus
491800 Canis lupus familiaris
100154894 Sus scrofa
541298 Bos taurus
331461 Mus musculus
317553 Rattus norvegicus
450116 Pan troglodytes
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