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Data suggest that the distinct spatial and temporal distribution patterns of KCTD8 (show KCTD8 ELISA Kits), 12, 12b, and 16 underlie functional differences in native GABA(B) responses.
Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization.
potassium channel tetramerisation domain containing 16
, BTB/POZ domain-containing protein KCTD16
, potassium channel tetramerization domain-containing protein 16