Browse our anti-Orexin (OX) Antibodies

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anti-Orexin Antibodies (OX)
On are 42 Orexin (OX) Antibodies from 11 different suppliers available. Additionally we are shipping Orexin Kits (34) and many more products for this protein. A total of 80 Orexin products are currently listed.
NRCLP1, orexin-A, OX, PPOX

Most Popular Reactivities for anti-Orexin (OX) Antibodies

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Top referenced anti-Orexin Antibodies

  1. Mouse (Murine) Polyclonal OX Primary Antibody for EIA, WB - ABIN492717 : Sakurai, Moriguchi, Furuya, Kajiwara, Nakamura, Yanagisawa, Goto: Structure and function of human prepro-orexin gene. in The Journal of biological chemistry 1999 (PubMed)
    Show all 5 references for 492717

More Antibodies against Orexin Interaction Partners

Mouse (Murine) Orexin (OX) interaction partners

  1. In ORX-KO mice, the ultradian episodic changes in locomotor activity, EEG arousal indices and body temperature were significantly attenuated, but the ultradian patterning was preserved. Findings suggest that the ultradian pattern is common across species and that orexin contributes to driving ultradian episodic changes, however, this neuropeptide is not essential for ultradian pattern generation.

  2. OXA and OX1R (show HCRTR1 Antibodies) are expressed in the testis and that they may help in proliferation and development of germ cells, Leydig cells and Sertoli cells, and in the spermatogenic process and steroidogenesis.

  3. Results thus suggest that type 1 diabetes mellitus impairs testicular steroidogenesis and glucose homeostasis through inhibition of orexin A/OX1R (show HCRTR1 Antibodies) signaling cascade due to decreased OX1R (show HCRTR1 Antibodies) expression in adult mice, thereby affecting germ cell survival and their proliferation in the testis.

  4. Binding of OXA to OX1R (show HCRTR1 Antibodies) is important for the development of the testis.

  5. Results suggest that orexin A bidirectionally modulates hippocampal CA1 (show CA1 Antibodies) synaptic plasticity, inhibiting long-term potentiation via OX1Rs at moderate concentrations while inducing re-potentiation via OX1Rs and OX2Rs, possibly through phospholipase C (show PLC Antibodies) and adenylyl cyclase-protein kinase A signaling at sub-nanomolar concentrations

  6. DYN (show PDYN Antibodies)-A(2-17) interacts with orexin A in the paraventricular hypothalamic nucleus to modulate food intake in mice.

  7. Awake dynamics and brain-wide direct inputs of hypothalamic MCH (show PMCH Antibodies) and orexin/hypocretin networks have been discovered.

  8. Histamine Transmission Modulates the Phenotype of Murine Narcolepsy Caused by Orexin Neuron Deficiency

  9. observation that inhibition of the Orexin-1 receptor signaling blunted binge-like Ethanol, and saccharin drinking suggests that reward-related Orexin circuits participate in the consumption of salient reinforcers regardless of calories.

  10. Results suggest that exercise produces antidepressant effects via suppression of Hcrt/Orx and melanin-concentrating hormone (show PMCH Antibodies) neural systems in the basolateral amygdala

Human Orexin (OX) interaction partners

  1. No association was observed between rs9902709 in HCRT and OSAHS (obstructive sleep apnea) risk in Chinese Han population.

  2. findings show that in few patients with narcolepsy with cataplexy, symptoms and CSF (show CSF2 Antibodies) hypocretin-1 and histamine levels can change over time

  3. actigraphy gives additional information about the stabilization of sleep in patients with narcolepsy type 1; very low hypocretin levels associate with more wake intruding into sleep

  4. There was also a negative correlation between Epworth sleepiness scale scores and orexin levels in Prader-Willi syndrome patients. Decreased cerebrospinal fluid orexin levels in Prader-Willi syndrome may play an important role in severity of obesity and excessive daytime sleepiness.

  5. orexin system may be involved even in the earliest stages of AD, resulting in prolonged sleep latency, reduced sleep efficiency, and REM (show REM1 Antibodies) sleep impairment.

  6. Rapid-onset obesity with hypothalamic dysfunction, hypoventilation, and autonomic dysregulation is highly unlikely to be caused by mutations in the exons of the gene for hypocretin.

  7. Data indicate a positive correlation of nesfatin-1 (show NUCB2 Antibodies) and a negative correlation of orexin-A with body mass index.

  8. This study showed that orexin A induced autophagy through the ERK (show EPHB2 Antibodies) pathway in HCT116 human colon cancer cells.

  9. This is the first time a seasonal variation of hcrt-1 levels has been shown, demonstrating that the hcrt system is, like other neurotransmitter systems, subjected to long term modulation

  10. Significantly reduced csf (show CSF2 Antibodies) levels of hypocretin-1 were found in cluster headache patients compared with controls.

Cow (Bovine) Orexin (OX) interaction partners

  1. The aim of the study was to determine by immunochemistry the expression of leptin (show LEP Antibodies), orexin A and orphanin FQ (show PNOC Antibodies) in the major salivary glands (parotid, submandibular and sublingual) of rat, sheep and cow.

  2. first evidence for the expression of oxA and ox1R (show HCRTR1 Antibodies) in the vestibular glands of mammalian genital tract

Pig (Porcine) Orexin (OX) interaction partners

  1. The impact of the phase of the estrous cycle on the observed changes in plasma orexin levels in domestic pigs.

Orexin (OX) Antigen Profile

Antigen Summary

This gene encodes a hypothalamic neuropeptide precursor protein that gives rise to two mature neuropeptides, orexin A and orexin B, by proteolytic processing. Orexin A and orexin B, which bind to orphan G-protein coupled receptors HCRTR1 and HCRTR2, function in the regulation of sleep and arousal. This neuropeptide arrangement may also play a role in feeding behavior, metabolism, and homeostasis.

Alternative names and synonyms associated with Orexin (OX)

  • hypocretin (Hcrt) antibody
  • hypocretin (orexin) neuropeptide precursor (HCRT) antibody
  • NRCLP1 antibody
  • orexin-A antibody
  • OX antibody
  • PPOX antibody

Protein level used designations for anti-Orexin (OX) Antibodies

Hypocretin (orexin) neuropeptide , orexin , orexin A , orexin B , prepro-orexin , hcrt1 , hypocretin-1 , orexin-A , orexin-B

25723 Rattus norvegicus
15171 Mus musculus
3060 Homo sapiens
101122291 Ovis aries
281222 Bos taurus
607641 Canis lupus familiaris
397305 Sus scrofa
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