anti-Human CBL antibody for Western Blotting

Recommended CBL Antibody (supplied by: Log in to see )

Antigen
Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL) Antibodies
  • 4732447J05Rik
  • Cbl-2
  • c-Cbl
  • cbl
  • C-CBL
  • CBL2
  • FRA11B
  • NSLL
  • RNF55
  • c-cbl-like
  • RGD1561386
  • Casitas B-lineage lymphoma
  • Cbl proto-oncogene, E3 ubiquitin protein ligase
  • Cbl
  • CBL
Epitope
AA 556-906
45
44
28
28
19
6
5
4
4
3
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
276
172
162
7
6
4
4
3
3
1
1
1
Host
Rabbit
220
45
16
1
Clonality
Polyclonal
Conjugate
This CBL antibody is un-conjugated
7
7
7
7
6
5
5
5
5
5
5
5
5
5
4
2
2
Application
Western Blotting (WB)
196
75
74
65
62
50
20
16
11
6
5
3
3
3
1
1
1
1
Options
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Catalog No. ABIN3043746
$ 240.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
2.905818 ABIN1531307 IF IHC ELISA WB Rabbit IgG pTyr700 Log in to see Polyclonal 1
2.905818 ABIN2704545 IC IF IHC WB Rabbit C-Term, pTyr700 Log in to see Polyclonal
2.905818 ABIN2704546 IC IF IHC WB Rabbit C-Term, pTyr774 Log in to see Polyclonal
2.905818 ABIN2705618 IHC WB Rabbit pTyr674 Log in to see Polyclonal
2.905818 ABIN388072 IHC (p) WB Rabbit Ig AA 424-453, C-Term Log in to see Polyclonal 1
2.905818 ABIN388071 IHC (p) WB Rabbit Ig AA 1-30, N-Term Log in to see Polyclonal 1
2.905818 ABIN967970 IF IP IHC WB Mouse IgG1 AA 595-810 Log in to see 17-c 5
2.905818 ABIN967971 IF IP IHC WB Mouse IgG1 AA 595-810 Log in to see 17-c 5
2.905818 ABIN968993 ICC FACS IHC ELISA WB Mouse IgG1 Log in to see 3B12 3
2.905818 ABIN3044183 WB Rabbit IgG AA 863-877, C-Term Log in to see Polyclonal
2.905818 ABIN968810 IF WB Mouse IgG1 pTyr700 Log in to see 47-c 2
2.905818 ABIN968811 IF WB Mouse IgG1 pTyr700 Log in to see 47-c 2
2.905818 ABIN1531306 IF IHC ELISA WB Rabbit IgG pTyr774 Log in to see Polyclonal
2.905818 ABIN1531308 IHC ELISA WB Rabbit IgG pTyr674 Log in to see Polyclonal
2.905818 ABIN967577 IHC (f) WB Mouse IgG1, kappa pTyr774 Log in to see 29-c 2
2.905818 ABIN1532325 IF IHC ELISA WB Rabbit IgG Log in to see Polyclonal
2.905818 ABIN1532326 IF IHC ELISA WB Rabbit IgG Log in to see Polyclonal
2.905818 ABIN1532327 IHC ELISA WB Rabbit IgG Log in to see Polyclonal
2.905818 ABIN3183702 ELISA IF IHC WB Rabbit IgG Ser208 Log in to see Polyclonal
2.905818 ABIN3183701 ELISA IF IHC WB Rabbit IgG Ser207 Log in to see Polyclonal

General

Antigen Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL) Antibodies
Epitope AA 556-906
(45), (44), (28), (28), (19), (6), (5), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(276), (172), (162), (7), (6), (4), (4), (3), (3), (1), (1), (1)
Host Rabbit
(220), (45), (16), (1)
Clonality
Polyclonal
Conjugate This CBL antibody is un-conjugated
(7), (7), (7), (7), (6), (5), (5), (5), (5), (5), (5), (5), (5), (5), (4), (2), (2)
Application Western Blotting (WB)
(196), (75), (74), (65), (62), (50), (20), (16), (11), (6), (5), (3), (3), (3), (1), (1), (1), (1)
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Product Details anti-CBL Antibody

Target Details CBL Application Details Handling Images
Purpose Rabbit IgG polyclonal antibody for E3 ubiquitin-protein ligase CBL(CBL) detection. Tested with WB in Human.
Cross-Reactivity (Details) No cross reactivity with other proteins.
Characteristics Rabbit IgG polyclonal antibody for E3 ubiquitin-protein ligase CBL(CBL) detection. Tested with WB in Human.
Gene Name: Cbl proto-oncogene, E3 ubiquitin protein ligase
Protein Name: E3 ubiquitin-protein ligase CBL
Purification Immunogen affinity purified.
Immunogen E.coli-derived human CBL recombinant protein (Position: A556-T906). Human CBL shares 84% amino acid (aa) sequence identity with mouse CBL.
Isotype IgG

Target Details CBL

Product Details anti-CBL Antibody Application Details Handling Images back to top
Antigen
Alternative Name CBL (CBL Antibody Abstract)
Background CBL(Cbl proto-oncogene) is also known as C-CBL, RNF55, CBL2 and E3 ubiquitin protein ligase. CBL is mapped to chromosome 11q23.3-qter by molecular characterization of the breakpoints in 2 somatic cell hybrids. The encoded protein is one of the enzymes required for targeting substrates for degradation by the proteasome. This protein mediates the transfer of ubiquitin from ubiquitin conjugating enzymes(E2) to specific substrates. This protein also contains an N-terminal phosphotyrosine binding domain that allows it to interact with numerous tyrosine-phosphorylated substrates and target them for proteasome degradation. As such it functions as a negative regulator of many signal transduction pathways. This gene has been found to be mutated or translocated in many cancers including acute myeloid leukaemia. Mutations in this gene are also the cause of Noonan syndrome-like disorder.

Synonyms: 4732447J05Rik antibody|C CBL antibody|Cas Br M (murine) ecotropic retroviral transforming sequence antibody|Cas-Br-M (murine) ecotropic retroviral transforming sequence antibody|Casitas B lineage lymphoma proto oncogene antibody|Casitas B-lineage lymphoma proto-oncogene antibody|CBL 2 antibody|cbl antibody|CBL_HUMAN antibody|CBL2 antibody|E3 ubiquitin protein ligase CBL antibody|E3 ubiquitin-protein ligase CBL antibody|Oncogene CBL2 antibody|Proto oncogene c CBL antibody|Proto-oncogene c-CBL antibody|RGD1561386 antibody|RING finger protein 55 antibody|RNF55 antibody|Signal transduction protein CBL antibody
Gene ID 867
UniProt P22681
Research Area Cancer, Transcription Factors, Proteolysis / Ubiquitin
Pathways TCR Signaling, Interferon-gamma Pathway, EGFR Signaling Pathway, EGFR Downregulation, VEGFR1 Specific Signals

Application Details

Product Details anti-CBL Antibody Target Details CBL Handling Images back to top
Application Notes WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for CBL is approximately 0.25 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.
Comment

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions For Research Use only

Handling

Product Details anti-CBL Antibody Target Details CBL Application Details Images back to top
Format Lyophilized
Reconstitution Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
Concentration 500 μg/mL
Buffer Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Images

Product Details anti-CBL Antibody Target Details CBL Application Details Handling back to top
Supplier Images
Western Blotting (WB) image for anti-Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL) (AA 556-906) antibody (ABIN3043746) anti-Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL) (AA 556-906) antibody