anti-Mouse (Murine) CBL antibody for Immunocytochemistry

Recommended CBL Antibody (supplied by: Log in to see )

Antigen
Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL) Antibodies
  • 4732447J05Rik
  • Cbl-2
  • c-Cbl
  • cbl
  • C-CBL
  • CBL2
  • FRA11B
  • NSLL
  • RNF55
  • c-cbl-like
  • RGD1561386
  • Casitas B-lineage lymphoma
  • Cbl proto-oncogene, E3 ubiquitin protein ligase
  • Cbl
  • CBL
Reactivity
Human, Mouse (Murine), Rat (Rattus)
276
171
161
7
6
4
4
3
3
1
1
1
Host
Mouse
221
44
16
1
Clonality
Monoclonal
Conjugate
This CBL antibody is un-conjugated
7
7
7
7
6
5
5
5
5
5
5
5
5
5
4
2
2
Application
Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
196
74
73
65
62
50
20
15
10
6
5
3
3
3
1
1
1
1
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Catalog No. ABIN968993
$ 430.10
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN211561 ICC IP WB Mouse IgG AA 878-906 Log in to see
1 ABIN4288401 ELISA FACS ICC IF IHC WB Mouse IgG1 Log in to see 3B12
1 ABIN2590840 ELISA FACS ICC IF IHC (p) WB Mouse IgG1 Log in to see 3B12
1 ABIN4288402 ICC IF IHC IHC (p) WB Rabbit IgG Log in to see Polyclonal
1 ABIN4880224 ELISA FACS ICC IHC WB Mouse IgG1 Log in to see 3B12
1 ABIN2590846 ICC IF IHC (p) WB Rabbit pTyr774 Log in to see Polyclonal
1 ABIN2738636 ICC IF IHC (p) WB Rabbit C-Term Log in to see Polyclonal
1 ABIN4288400 ICC IF IHC IHC (p) WB Rabbit Log in to see Polyclonal

General

Antigen Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL) Antibodies
Reactivity Human, Mouse (Murine), Rat (Rattus)
(276), (171), (161), (7), (6), (4), (4), (3), (3), (1), (1), (1)
Host Mouse
(221), (44), (16), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This CBL antibody is un-conjugated
(7), (7), (7), (7), (6), (5), (5), (5), (5), (5), (5), (5), (5), (5), (4), (2), (2)
Application Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
(196), (74), (73), (65), (62), (50), (20), (15), (10), (6), (5), (3), (3), (3), (1), (1), (1), (1)
Pubmed 3 references available
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Product Details anti-CBL Antibody

Target Details CBL Application Details Handling ProductDetails: References for anti-CBL antibody (ABIN968993) Images
Purification Ascites
Immunogen Purified recombinant fragment of human C-CBL expressed in E. Coli.
Clone 3B12
Isotype IgG1

Target Details CBL

Product Details anti-CBL Antibody Application Details Handling ProductDetails: References for anti-CBL antibody (ABIN968993) Images back to top
Antigen
Alternative Name C-CBL (CBL Antibody Abstract)
Background The cbl oncogene was first identified as part of a transforming retrovirus which induces mouse pre-B and pro-B cell lymphomas. As an adaptor protein for receptor protein-tyrosine kinases, it positively regulates receptor protein-tyrosine kinase ubiquitination in a manner dependent upon its variant SH2 and RING finger domains. Ubiquitination of receptor protein-tyrosine kinases terminates signaling by marking active receptors for degradation.
Molecular Weight 120 kDa
Gene ID 867
HGNC 867
Pathways TCR Signaling, Interferon-gamma Pathway, EGFR Signaling Pathway, EGFR Downregulation, VEGFR1 Specific Signals

Application Details

Product Details anti-CBL Antibody Target Details CBL Handling ProductDetails: References for anti-CBL antibody (ABIN968993) Images back to top
Application Notes ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
Restrictions For Research Use only

Handling

Product Details anti-CBL Antibody Target Details CBL Application Details ProductDetails: References for anti-CBL antibody (ABIN968993) Images back to top
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment 4°C, -20°C for long term storage

ProductDetails: References for anti-CBL antibody (ABIN968993)

Product Details anti-CBL Antibody Target Details CBL Application Details Handling Images back to top
Product cited in:

Sproul, Xu, Wilhelm, Gire, Greene: "Cbl negatively regulates JNK activation and cell death." in: Cell research, Vol. 19, Issue 8, pp. 950-61, 2009

Sanada, Suzuki, Shih, Otsu, Kato, Yamazaki, Tamura, Honda, Sakata-Yanagimoto, Kumano, Oda, Yamagata, Takita, Gotoh, Nakazaki, Kawamata, Onodera, Nobuyoshi, Hayashi, Harada, Kurokawa, Chiba, Mori et al.: "Gain-of-function of mutated C-CBL tumour suppressor in myeloid neoplasms. ..." in: Nature, Vol. 460, Issue 7257, pp. 904-8, 2009

Loh, Sakai, Flotho, Kang, Fliegauf, Archambeault, Mullighan, Chen, Bergstraesser, Bueso-Ramos, Emanuel, Hasle, Issa, van den Heuvel-Eibrink, Locatelli, Stary, Trebo, Wlodarski, Zecca, Shannon et al.: "Mutations in CBL occur frequently in juvenile myelomonocytic leukemia. ..." in: Blood, Vol. 114, Issue 9, pp. 1859-63, 2009

Images

Product Details anti-CBL Antibody Target Details CBL Application Details Handling ProductDetails: References for anti-CBL antibody (ABIN968993) back to top
Supplier Images
ELISA image for anti-Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL) antibody (ABIN968993) Figure 1: Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green: Antigen (50 n...
Flow Cytometry (FACS) image for anti-Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL) antibody (ABIN968993) Figure 2: Flow cytometric analysis of MCF-7 cells using C-CBL mouse mAb (blue) and ne...
Immunocytochemistry (ICC) image for anti-Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL) antibody (ABIN968993) Figure 3: Immunofluorescence analysis of Hela cells using C-CBL mouse mAb (green) . B...
Immunohistochemistry (IHC) image for anti-Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL) antibody (ABIN968993) Figure 4: Immunohistochemical analysis of paraffin-embedded ovarian cancer tissues us...
Immunohistochemistry (IHC) image for anti-Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL) antibody (ABIN968993) Figure 5: Immunohistochemical analysis of paraffin-embedded bladder cancer tissues us...
Western Blotting (WB) image for anti-Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL) antibody (ABIN968993) Figure 6: Western blot analysis using C-CBL mouse mAb against RAJI (1), RAW264.7 (2),...
Western Blotting (WB) image for anti-Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL) antibody (ABIN968993) Figure 7: Western blot analysis using C-CBL mAb against human C-CBL (AA: 684-865) rec...