You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Rat (Rattus) CBL antibody for Fluorescence Microscopy

Recommended CBL Antibody (supplied by: Log in to see )

Antigen
Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL) Antibodies
  • 4732447J05Rik
  • C-CBL
  • c-Cbl
  • c-cbl-like
  • cbl
  • Cbl-2
  • CBL2
  • FRA11B
  • NSLL
  • RGD1561386
  • RNF55
Reactivity
Human, Mouse (Murine), Rat (Rattus)
249
134
128
6
4
4
4
1
1
1
Host
Rabbit
201
36
16
1
Clonality
Polyclonal
Conjugate
This CBL antibody is un-conjugated
7
7
7
7
6
5
5
5
5
5
5
5
4
2
2
Application
Fluorescence Microscopy (FM), ELISA, Western Blotting (WB)
168
71
66
55
55
32
18
17
6
5
4
3
3
1
1
1
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

It's quick and easy to submit your validation proposal. I want to validate this product

Learn more

Catalog No. ABIN1001990
$ 455.07
Plus shipping costs $45.00

Top referenced anti-CBL antibody for Fluorescence Microscopy

Similar anti-CBL Antibodies

Application / Reactivity Rat (Rattus) Mouse (Murine)
ELISA 31 Antibodies 35 Antibodies
Enzyme Immunoassay (EIA) 4 Antibodies 4 Antibodies
Flow Cytometry (FACS) 4 Antibodies 4 Antibodies
Fluorescence Microscopy (FM) 1 Antibodies 1 Antibodies
Immunochromatography (IC) 2 Antibodies 2 Antibodies
Immunocytochemistry (ICC) 6 Antibodies 6 Antibodies
Immunofluorescence (IF) 27 Antibodies 27 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 55 Antibodies
Immunohistochemistry (IHC) 37 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 23 Antibodies
Immunoprecipitation (IP) 5 Antibodies
Western Blotting (WB) 75 Antibodies

General

Antigen Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL) Antibodies
Reactivity Human, Mouse (Murine), Rat (Rattus)
(249), (134), (128), (6), (4), (4), (4), (1), (1), (1)
Host Rabbit
(201), (36), (16), (1)
Clonality
Polyclonal
Conjugate This CBL antibody is un-conjugated
(7), (7), (7), (7), (6), (5), (5), (5), (5), (5), (5), (5), (4), (2), (2)
Application Fluorescence Microscopy (FM), ELISA, Western Blotting (WB)
(168), (71), (66), (55), (55), (32), (18), (17), (6), (5), (4), (3), (3), (1), (1), (1), (1)
Pubmed 3 references available
Supplier Log in to see

Product Details anti-CBL Antibody

Target Details CBL Application Details Handling References for anti-CBL Antibody (ABIN1001990) Images
Blocking Peptide Blocking peptide for this product available: ABIN1004304
Purification Affinity chromatography purified via peptide column.
Immunogen Cbl antibody was raised against a 14 amino acid peptide from near the carboxy terminus of human cbl.
Isotype IgG

Target Details CBL

Product Details anti-CBL Antibody Application Details Handling References for anti-CBL Antibody (ABIN1001990) Images back to top
Antigen
Alternative Name Casitas B-lineage Lymphoma Proto-Oncogene (CBL Antibody Abstract)
Background The mammalian cbl family of ubiquitin ligases consists of three homologs known as cbl (also known as c-Cbl), Cbl-B, and Cbl-3 which share highly conserved a tyrosine-kinase-binding domain, linker and RING finger domain in their amino-terminal halves. Similar to other E3 ubiquitin ligases, Cbl catalyzes the transfer of ubiquitin from an E2 or Ubc (ubiquitin-conjugating) enzyme to the e-amino group of a lysine residue of the substrate protein. Cbl acts to negatively regulate many types of cell-surface receptors, including the Syk protein tyrosine kinase family. Cbl is thought to be involved in T- and B-cell signaling, in addition to thymus development. Of the three known homologs in the cbl family, cbl antibody reacts specifically with cbl. Multiple isoforms of cbl have been reported.
Pathways TCR Signaling, Interferon-gamma Pathway, EGFR Signaling Pathway

Application Details

Product Details anti-CBL Antibody Target Details CBL Handling References for anti-CBL Antibody (ABIN1001990) Images back to top
Application Notes Cbl antibody can be used for detection of cbl by Western blot at 0.5 – 1 µg/ml. (Optimal dilution should be determined by user.) Antibody can also be used for immunofluorescence microscopy and ELISA and might be suited for other applications not tested so far.
Restrictions For Research Use only

Handling

Product Details anti-CBL Antibody Target Details CBL Application Details References for anti-CBL Antibody (ABIN1001990) Images back to top
Format Liquid
Buffer Antibody is supplied in PBS containing 0.02% sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Antibody can be stored at 4 °C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. During shipment, small volumes of antibody will occasionally become entrapped in the seal of the product vial. For products with volumes of 200 myl or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap.
Storage 4 °C
Expiry Date 12 months

References for anti-CBL Antibody (ABIN1001990)

Product Details anti-CBL Antibody Target Details CBL Application Details Handling Images back to top
Background publications

Swaminathan, Tsygankov: "The Cbl family proteins: ring leaders in regulation of cell signaling." in: Journal of cellular physiology, Vol. 209, Issue 1, pp. 21-43, 2006

Weissman: "Themes and variations on ubiquitylation." in: Nature reviews. Molecular cell biology, Vol. 2, Issue 3, pp. 169-78, 2001

Product cited in:

Thien, Langdon: "c-Cbl and Cbl-b ubiquitin ligases: substrate diversity and the negative regulation of signalling responses." in: The Biochemical journal, Vol. 391, Issue Pt 2, pp. 153-66, 2005