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Browse our CBL (CBL) ELISA Kits

Full name:
Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence ELISA Kits (CBL)
On www.antibodies-online.com are 12 Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL) ELISA Kits from 5 different suppliers available. Additionally we are shipping CBL Antibodies (252) and CBL Proteins (5) and many more products for this protein. A total of 291 CBL products are currently listed.
Synonyms:
4732447J05Rik, C-CBL, c-cbl-like, cbl, Cbl-2, CBL2, FRA11B, NSLL, RGD1561386, RNF55
list all ELISA KIts Gene Name GeneID UniProt
CBL 12402 P22682
CBL 867 P22681
CBL 500985  

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CBL (CBL) ELISA Kits by Reactivity

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More ELISA Kits for CBL Interaction Partners

Mouse (Murine) Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL) interaction partners

  1. Cbl down-regulation protects mice against high-fat diet-induced obesity and insulin (show INS ELISA Kits) resistance.

  2. Cbl-b and c-Cbl regulate the degradation of Osterix through the ubiquitin-proteasome pathway.

  3. Overexpression of Smad7 (show SMAD7 ELISA Kits) in human HaCaT keratinocyte cells and mouse skin tissues elevated EGF receptor (EGFR (show EGFR ELISA Kits)) activity by impairing ligand-induced ubiquitination and degradation of activated receptor, which is induced by the E3 ubiquitin ligase c-Cbl.

  4. Erbin (show ERBB2IP ELISA Kits) promotes tumourigenesis and tumour growth in colorectal cancer by stabilizing epidermal growth factor receptor (show EGFR ELISA Kits)

  5. Whereas Cbl-PI3K interaction regulates differentiation and survival, bone resorption is predominantly regulated by Cbl-b in osteoclasts.

  6. c-Cbl activation promotes myocyte apoptosis, inhibits angiogenesis, and causes adverse cardiac remodeling after myocardial infarction.

  7. Data indicate a Cbl/p85 (show ECM1 ELISA Kits)/epsin-1 (show EPN1 ELISA Kits) pathway in erythropoietin receptor (EpoR (show EPOR ELISA Kits)) endocytosis.

  8. These results support the notion that the distal cytoplasmic domain of CD5 (show CD5 ELISA Kits), including Y463, plays a relevant role in the downmodulation of TCR signals in thymocytes via c-Cbl.

  9. c-Cbl conjugates neural precursor cell-expressed, developmentally downregulated 8 (NEDD8), a ubiquitin-like protein, to TbetaRII at Lys556 and Lys567.

  10. the novel role for Syk (show SYK ELISA Kits) signaling and the Syk (show SYK ELISA Kits)-binding ubiquitin ligase (show RNF123 ELISA Kits) c-Cbl in the BCR (show BCR ELISA Kits)-mediated processing and presentation of cognate antigen and

Human Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL) interaction partners

  1. H19 non coding RNA-derived miR-675 enhances tumorigenesis and metastasis of breast cancer cells by downregulating c-Cbl and Cbl-b.

  2. The study reveals a role of CBL in restricting myeloid proliferation of human AML1 (show RUNX1 ELISA Kits)-ETOinduced leukemia, and identifies UBASH3B (show STS1 ELISA Kits) as a potential target for pharmaceutical intervention.

  3. By up-regulating the expression of c-Cbl and Cbl-b, which leads to inhibition of PI3K (show PIK3CA ELISA Kits)/Akt (show AKT1 ELISA Kits) signaling and down-regulation of P-gp (show ABCB4 ELISA Kits) expression, beta-elemene is capable of enhancing the efficacy of doxorubicin in leukemia and gastric cancer cells.

  4. Genotype-phenotype correlation analysis performed on available records indicated that germline CBL mutations cause a variable phenotype characterized by a relatively high frequency of neurological features, predisposition to diseases.

  5. The result indicated that TMZ may overcome TRAIL resistance in GSCs by suppressing c-FLIP (show CFLAR ELISA Kits) expression through c-Cbl-mediated ubiquitination and degradation

  6. Demonstrate role for CBL in the control of AXL (show AXL ELISA Kits)/SYK (show SYK ELISA Kits)/LYN (show LYN ELISA Kits) network mediating resistance to nilotinib treatment in chronic myeloid leukemia (show BCL11A ELISA Kits) cells.

  7. Overexpression of Smad7 (show SMAD7 ELISA Kits) in human HaCaT keratinocyte cells and mouse skin tissues elevated EGF receptor (EGFR (show EGFR ELISA Kits)) activity by impairing ligand-induced ubiquitination and degradation of activated receptor, which is induced by the E3 ubiquitin ligase c-Cbl.

  8. Here we report on three unrelated patients with CBL mutations manifesting with hydrops fetalis, fetal pleural effusions and/or congenital hydro-/chylothorax. Our findings further connect the CBL syndrome with the RASopathies.

  9. These results suggest that dysregulation of ubiquitination is a key mechanism of EGFR (show EGFR ELISA Kits) hyperactivation in PDAC and that low CBL may define PDAC tumors likely to respond to erlotinib treatment.

  10. The penetrance of the CBL Y371C mutation was 30% for JMML and 40% for all leukemia.

CBL Antigen Profile

Antigen Summary

This gene is a proto-oncogene that encodes a RING finger E3 ubiquitin ligase. The encoded protein is one of the enzymes required for targeting substrates for degradation by the proteasome. This protein mediates the transfer of ubiquitin from ubiquitin conjugating enzymes (E2) to specific substrates. This protein also contains an N-terminal phosphotyrosine binding domain that allows it to interact with numerous tyrosine-phosphorylated substrates and target them for proteasome degradation. As such it functions as a negative regulator of many signal transduction pathways. This gene has been found to be mutated or translocated in many cancers including acute myeloid leukaemia. Mutations in this gene are also the cause of Noonan syndrome-like disorder.

Alternative names and synonyms associated with CBL

  • Casitas B-lineage lymphoma (Cbl) Elisa Kit
  • Cbl proto-oncogene, E3 ubiquitin protein ligase (CBL) Elisa Kit
  • Cbl proto-oncogene, E3 ubiquitin protein ligase (Cbl) Elisa Kit
  • 4732447J05Rik Elisa Kit
  • C-CBL Elisa Kit
  • c-cbl-like Elisa Kit
  • cbl Elisa Kit
  • Cbl-2 Elisa Kit
  • CBL2 Elisa Kit
  • FRA11B Elisa Kit
  • NSLL Elisa Kit
  • RGD1561386 Elisa Kit
  • RNF55 Elisa Kit

Protein level used designations for CBL

E3 ubiquitin-protein ligase CBL , casitas B-lineage lymphoma proto-oncogene , proto-oncogene c-CBL , signal transduction protein CBL , Cas-Br-M (murine) ecotropic retroviral transforming sequence , RING finger protein 55 , fragile site, folic acid type, rare, fra(11)(q23.3) , oncogene CBL2 , proto-oncogene c-Cbl , Casitas B-lineage lymphoma

GENE ID SPECIES
12402 Mus musculus
867 Homo sapiens
489369 Canis lupus familiaris
100518854 Sus scrofa
527418 Bos taurus
500985 Rattus norvegicus
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