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anti-Human CD137 antibody for Flow Cytometry

Recommended CD137 Antibody (supplied by: Log in to see )

Antigen
Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9) Antibodies
  • 4-1BB
  • A930040I11Rik
  • AA408498
  • AI325004
  • CD137
  • Cd137
  • CDw137
  • ILA
  • Ly63
  • TNFRSF9
  • zgc:136557
Reactivity
Human
156
76
16
9
3
1
Host
Mouse
75
49
41
26
25
Clonality
Monoclonal
Conjugate
This CD137 antibody is conjugated to Alexa Fluor 700
25
19
15
5
2
2
2
2
2
2
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS)
137
85
75
21
20
15
12
7
7
6
5
2
2
2
1
1
1
1
1
Supplier
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Catalog No. ABIN2657240
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.28290245 ABIN2660941 FACS Biotin Mouse IgG1 kappa Log in to see 4B4-1 8
0.28290245 ABIN2663017 FACS IF PE Mouse IgG1 kappa Log in to see 4B4-1 8
0.28290245 ABIN2660273 FACS PerCP-Cy5.5 Mouse IgG1 kappa Log in to see 4B4-1 8
0.28290245 ABIN2658481 FACS APC Mouse IgG1 kappa Log in to see 4B4-1 10
0.28290245 ABIN2665542 FACS Mouse IgG1 kappa Log in to see 4B4-1 8
0.28290245 ABIN2664205 FACS Mouse IgG1 kappa Log in to see 4B4-1 8
0.28290245 ABIN262814 FACS Biotin Mouse IgG1 kappa Log in to see 4B4-1
0.28290245 ABIN262813 FACS IP ELISA Mouse IgG1 kappa Log in to see 4B4-1
0.28290245 ABIN1169065 FACS WB Rabbit Log in to see Polyclonal
0.28290245 ABIN4896671 FACS PE Mouse IgG2b AA 24-186 Log in to see 145501
0.28290245 ABIN4899793 ELISA (Detection) FACS ICC WB Biotin Goat IgG AA 24-186 Log in to see Polyclonal 1
0.28290245 ABIN4899794 FACS WB Mouse IgG2b AA 24-186 Log in to see 145501
0.28290245 ABIN4899795 FACS WB Mouse IgG2b AA 24-186 Log in to see 145501
0.0010564557 ABIN610408 Func FACS ELISA FITC Mouse IgG1, kappa Log in to see 4B4-1 4
0.0010564557 ABIN474083 FACS FITC Mouse IgG1, kappa Log in to see 4B4 (4B4-1)
0.0010564557 ABIN958288 Func ICC FACS ELISA WB Goat IgG Log in to see Polyclonal
0.0010564557 ABIN180377 FACS IF Mouse IgG1 Log in to see BBK-2
0.0010564557 ABIN610409 Func FACS ELISA PE Mouse IgG1, kappa Log in to see 4B4-1
0.0010564557 ABIN610407 Func FACS ELISA Biotin Mouse IgG1, kappa Log in to see 4B4-1
0.0010564557 ABIN1837865 FACS PE Mouse IgG1 Log in to see 4B4-1

Top referenced anti-CD137 antibody for Flow Cytometry

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Application / Reactivity Human
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Functional Studies (Func) 18 Antibodies
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General

Antigen Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9) Antibodies
Reactivity Human
(156), (76), (16), (9), (3), (1)
Host Mouse
(75), (49), (41), (26), (25)
Clonality (Clone)
Monoclonal   ( )
Conjugate This CD137 antibody is conjugated to Alexa Fluor 700
(25), (19), (15), (5), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Application Flow Cytometry (FACS)
(137), (85), (75), (21), (20), (15), (12), (7), (7), (6), (5), (2), (2), (2), (1), (1), (1), (1), (1)
Pubmed 8 references available
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Product Details anti-CD137 Antibody

Target Details CD137 Application Details Handling References for anti-CD137 Antibody (ABIN2657240) Images
Cross-Reactivity Chimpanzee, Baboon, Cynomolgus, Rhesus Monkey
Purification The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 700 under optimal conditions.
Clone 4B4-1
Isotype IgG1 kappa

Target Details CD137

Product Details anti-CD137 Antibody Application Details Handling References for anti-CD137 Antibody (ABIN2657240) Images back to top
Antigen
Alternative Name CD137 (TNFRSF9 Antibody Abstract)
Background CDw137 is a 39 kD transmembrane protein also known as 4-1BB. It is expressed on activated T cells. CDw137 is a type I membrane protein and a member of the tumor necrosis factor receptor superfamily. CDw137 appears to be important for T cell proliferation and survival, and induces monocyte activation through its interaction with 4-1BB ligand.
Research Area Stem Cells, Hematopoietic Progenitors, Cytokines, Innate Immunity, CD Antigens, Apoptosis/Necrosis, Surface Receptors of Immune Cells
Pathways TCR Signaling

Application Details

Product Details anti-CD137 Antibody Target Details CD137 Handling References for anti-CD137 Antibody (ABIN2657240) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-CD137 Antibody Target Details CD137 Application Details References for anti-CD137 Antibody (ABIN2657240) Images back to top
Concentration 0.5 mg/mL
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Protect from prolonged exposure to light. Do not freeze.
Storage 4 °C
Storage Comment The antibody solution should be stored undiluted between 2°C and 8°C

References for anti-CD137 Antibody (ABIN2657240)

Product Details anti-CD137 Antibody Target Details CD137 Application Details Handling Images back to top
Background publications

Sica, Chen: "Modulation of the immune response through 4-1BB." in: Advances in experimental medicine and biology, Vol. 465, pp. 355-62, 2000

Kienzle, von Kempis: "CD137 (ILA/4-1BB), expressed by primary human monocytes, induces monocyte activation and apoptosis of B lymphocytes." in: International immunology, Vol. 12, Issue 1, pp. 73-82, 2000

Salih, Kosowski, Haluska, Starling, Loo, Lee, Aruffo, Trail, Kiener: "Constitutive expression of functional 4-1BB (CD137) ligand on carcinoma cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 165, Issue 5, pp. 2903-10, 2000

Langstein, Michel, Fritsche, Kreutz, Andreesen, Schwarz: "CD137 (ILA/4-1BB), a member of the TNF receptor family, induces monocyte activation via bidirectional signaling." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 160, Issue 5, pp. 2488-94, 1998

Schwarz, Blanco, von Kempis, Valbracht, Lotz: "ILA, a member of the human nerve growth factor/tumor necrosis factor receptor family, regulates T-lymphocyte proliferation and survival." in: Blood, Vol. 87, Issue 7, pp. 2839-45, 1996

Garni-Wagner, Lee, Kim, Wilde, Kang, Kwon: "4-1BB is expressed on CD45RAhiROhi transitional T cell in humans." in: Cellular immunology, Vol. 169, Issue 1, pp. 91-8, 1996

Gruss, Dower: "Tumor necrosis factor ligand superfamily: involvement in the pathology of malignant lymphomas." in: Blood, Vol. 85, Issue 12, pp. 3378-404, 1995

Alderson, Smith, Tough, Davis-Smith, Armitage, Falk, Roux, Baker, Sutherland, Din: "Molecular and biological characterization of human 4-1BB and its ligand." in: European journal of immunology, Vol. 24, Issue 9, pp. 2219-27, 1994

Images

Product Details anti-CD137 Antibody Target Details CD137 Application Details Handling References for anti-CD137 Antibody (ABIN2657240) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-CD137 antibody (Tumor Necrosis Factor Receptor Superfamily, Member 9)  (Alexa Fluor 700) (ABIN2657240) anti-Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9) antibody (Alexa Fluor 700)