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anti-Human CD247 antibody for Functional Studies

Recommended CD247 Antibody (supplied by: Log in to see )

Antigen
CD247 Molecule (CD247) Antibodies
  • 4930549J05Rik
  • A430104F18Rik
  • AW552088
  • Cd3
  • Cd3-eta
  • CD3-ZETA
  • Cd3-zeta
  • CD3H
  • Cd3h
  • CD3Q
  • Cd3z
  • CD3Z
  • Cd3zeta
  • CD247
  • im:7156386
  • LOC100136514
  • LOC100136549
  • LOC100305023
  • T3Z
  • T3z
  • Tcrk
  • Tcrz
  • TCRZ
  • TCRzeta
Reactivity
Human
189
69
28
4
2
2
1
Host
Mouse
97
93
11
1
Clonality
Monoclonal
Conjugate
This CD247 antibody is un-conjugated
25
17
7
4
4
4
2
1
1
Application
Functional Studies (Func), Immunofluorescence (IF), Microcytotoxicity Assay (MCA)
144
100
87
31
28
21
15
12
12
8
3
1
1
Supplier
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Catalog No. ABIN1106128
$ 253.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.000873873 ABIN480375 Func IP ELISA WB Mouse IgG1 Cytoplasmic Domain Log in to see

Similar anti-CD247 Antibodies

Application / Reactivity Human
ELISA 78 Antibodies
Enzyme Immunoassay (EIA) 8 Antibodies
Flow Cytometry (FACS) 93 Antibodies
Functional Studies (Func) 2 Antibodies
Immunocytochemistry (ICC) 12 Antibodies
Immunofluorescence (IF) 24 Antibodies
Immunohistochemistry (IHC) 28 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 11 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 15 Antibodies
Immunoprecipitation (IP) 31 Antibodies
Intracellular Staining (ICS) 3 Antibodies
Microcytotoxicity Assay (MCA) 1 Antibodies
Proximity Ligation Assay (PLA) 1 Antibodies
Western Blotting (WB) 133 Antibodies

General

Antigen CD247 Molecule (CD247) Antibodies
Reactivity Human
(189), (69), (28), (4), (2), (2), (1)
Host Mouse
(97), (93), (11), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This CD247 antibody is un-conjugated
(25), (17), (7), (4), (4), (4), (2), (1), (1)
Application Functional Studies (Func), Immunofluorescence (IF), Microcytotoxicity Assay (MCA)
(144), (100), (87), (31), (28), (21), (15), (12), (12), (8), (3), (1), (1)
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Product Details anti-CD247 Antibody

Target Details CD247 Application Details Handling Images
Specificity The antibody reacts with the T-cell specific antigen CD3. Binding of WT32 to T-cells is blocked by OKT3 and immunoprecipitation with WT32 yields a pattern of bands similar to that obtained with OKT3. WT32 is mitogenic for Human Tcells, it inhibits T-cell mediated cytotoxicity, and can induce non-specific cytotoxicity.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Ascites
Clone WT32
Isotype IgG2a

Target Details CD247

Product Details anti-CD247 Antibody Application Details Handling Images back to top
Antigen
Alternative Name CD247 / CD3Z (CD247 Antibody Abstract)
Background CD3 complex is crucial in transducing antigen-recognition signals into the cytopasm of T cells and in regulating the cell surface expression of the TCR complex. T cell activation through the antigen receptor (TCR) involves the cytoplasmic tails of the CD3 subunits CD3 gamma, CD3 delta, CD3 epsilon and CD3 zeta (CD247). These CD3 subunits are structurally related members of the immunoglobulins super family encoded by closely linked genes on human chromosome 11. The CD3 components have long cytoplasmic tails that associate with cytoplasmic signal transduction molecules. This association is mediated at least in part by a double tyrosine-based motif present in a single copy in the CD3 subunits. CD3 may play a role in TCR-induced growth arrest, cell survival and proliferation.Synonyms: CD3 zeta chain, T-cell receptor T3 zeta chain, T-cell surface glycoprotein CD3 zeta chain, T3Z, TCRZ
Gene ID 12503
NCBI Accession NP_001106862
UniProt P24161
Research Area CD Antigens, Surface Receptors of Immune Cells
Pathways TCR Signaling

Application Details

Product Details anti-CD247 Antibody Target Details CD247 Handling Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-CD247 Antibody Target Details CD247 Application Details Images back to top
Format Liquid
Buffer PBS, 0.09 % Sodium Azide, 1 % BSA
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store the antibody undiluted at 2-8 °C.