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|Antigen||CD4 Molecule (CD4) Antibodies|
|Reactivity||Cat (Feline) Alternatives|
|Conjugate||This CD4 antibody is conjugated to FITC Alternatives|
Flow Cytometry (FACS)
|3 references available|
|Supplier||Log in to see|
Product Details anti-CD4 AntibodyTarget Details CD4 Application Details Handling References for anti-CD4 antibody (ABIN371323) Images
|Specificity||This antibody recognizes Feline CD4 (Mr. 65 kDa)|
|Characteristics||Synonyms: T4/Leu3, T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4|
Target Details CD4Product Details anti-CD4 Antibody Application Details Handling References for anti-CD4 antibody (ABIN371323) Images back to top
|Alternative Name||CD4 (CD4 Antibody Abstract)|
|Background||CD4 is a single chain transmembraneous glycoprotein (59 kDa) which belongs to the immunoglobulin superfamily. CD4 is present on a subset of T lymphocytes ("helper/inducer" T cells) and is also expressed at a lower level on monocytes, tissue macrophages and granulocytes. The antigen is involved in binding to MHC class II molecules. The intracellular domain of the antigen is associated with p56lck protein tyrosine kinase.Synonyms: T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4|
|Research Area||Immunology, Adaptive Immunity, Hematopoietic Progenitors, CD Antigens, Surface Receptors of Immune Cells|
|Pathways||TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events|
Application DetailsProduct Details anti-CD4 Antibody Target Details CD4 Handling References for anti-CD4 antibody (ABIN371323) Images back to top
Flow Cytometry: < / = 1 μg/10^6 cells. (Ref.1-3)
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-CD4 Antibody Target Details CD4 Application Details References for anti-CD4 antibody (ABIN371323) Images back to top
|Buffer||PBS containing 0.09 % Sodium Azide as preservative.|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Storage||4 °C/-20 °C|
Store the antibody undiluted at 2-8 °C for one month or in (aliquots) at -20 °C for longer. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
|Expiry Date||12 months|
References for anti-CD4 antibody (ABIN371323)Product Details anti-CD4 Antibody Target Details CD4 Application Details Handling Images back to top
Dean, Quackenbush, Ackley, Cooper, Hoover: "Flow cytometric analysis of T-lymphocyte subsets in cats." in: Veterinary immunology and immunopathology, Vol. 28, Issue 3-4, pp. 327-35, 1991
Ackley, Hoover, Cooper: "Identification of a CD4 homologue in the cat." in: Tissue antigens, Vol. 35, Issue 2, pp. 92-8, 1990
Ackley, Yamamoto, Levy, Pedersen, Cooper: "Immunologic abnormalities in pathogen-free cats experimentally infected with feline immunodeficiency virus." in: Journal of virology, Vol. 64, Issue 11, pp. 5652-5, 1990
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