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|Antigen||CD4 Molecule (CD4) Antibodies|
|Reactivity||Cat (Feline) Alternatives|
|Conjugate||This CD4 antibody is conjugated to FITC Alternatives|
Flow Cytometry (FACS), Immunohistochemistry (IHC)
|2 references available|
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Product Details anti-CD4 AntibodyTarget Details CD4 Application Details Handling References for anti-CD4 antibody (ABIN135501) Images
|Characteristics||The antibody detects: Feline CD4, Mr 65 kDa|
Target Details CD4Product Details anti-CD4 Antibody Application Details Handling References for anti-CD4 antibody (ABIN135501) Images back to top
|Alternative Name||CD4 (CD4 Antibody Abstract)|
|Background||Feline CD4, a member of the immunoglobulin superfamily of cell surface receptors, is a type I transmembrane glycoprotein that is expressed on the helper/inducer subpopulation of peripheral T lymphocytes. It is present on approximately 55 % of thymocytes, 15 % of splenocytes, 40 % of lymph node cells, and 25 % of peripheral blood lymphocytes. CD4 functions as an accessory molecule in the recognition of foreign antigens in association with MHC Class II antigens by T cells.|
|Research Area||Immunology, Adaptive Immunity, Hematopoietic Progenitors, CD Antigens, Surface Receptors of Immune Cells|
|Pathways||TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events|
Application DetailsProduct Details anti-CD4 Antibody Target Details CD4 Handling References for anti-CD4 antibody (ABIN135501) Images back to top
FACS: 1 µg/10^6 cells
Representative data are included in this product insert.
Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
|Sample Volume||1 mL|
|Restrictions||For Research Use only|
HandlingProduct Details anti-CD4 Antibody Target Details CD4 Application Details References for anti-CD4 antibody (ABIN135501) Images back to top
|Buffer||Product is supplied as 0.5 mg in 1.0 mL of PBS / NaN3.|
|Precaution of Use||WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.|
Protect conjugated products from light.
Each reagent is stable for the period shown on the bottle label if stored as directed.
References for anti-CD4 antibody (ABIN135501)Product Details anti-CD4 Antibody Target Details CD4 Application Details Handling Images back to top
Dean, Quackenbush, Ackley, Cooper, Hoover: "Flow cytometric analysis of T-lymphocyte subsets in cats." in: Veterinary immunology and immunopathology, Vol. 28, Issue 3-4, pp. 327-35, 1991
Ackley, Hoover, Cooper: "Identification of a CD4 homologue in the cat." in: Tissue antigens, Vol. 35, Issue 2, pp. 92-8, 1990
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