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anti-Human CD4 antibody for Complement Mediated Cell Depletion

Recommended CD4 Antibody (supplied by: Log in to see )

Antigen
CD4 Molecule (CD4) Antibodies
  • cd4
  • CD4mut
  • L3T4
  • Ly-4
  • p55
  • W3/25
Reactivity
Human
1067
630
221
61
44
43
23
22
21
19
18
15
13
9
8
7
7
6
5
5
4
3
2
2
2
2
1
1
Host
Rat
1240
588
236
4
2
1
Clonality
Monoclonal
Conjugate
This CD4 antibody is conjugated to PE
267
230
164
114
39
36
36
33
31
30
26
24
21
17
16
15
13
12
11
11
11
10
10
10
10
10
9
8
8
7
5
5
5
4
4
4
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Application
Activation (Act), Blocking Reagent (BR), Complement Mediated Cell Depletion (CMCD), Depletion (Dep), Flow Cytometry (FACS), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
1575
393
362
299
286
255
158
91
83
69
33
28
26
18
14
11
10
9
7
7
6
6
5
5
5
4
2
2
2
2
2
1
1
1
1
1
1
1
Supplier
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Available images

Catalog No. ABIN2662640
Contact our Customer Service for availability and price in your country.
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.00086569745 ABIN2662641 Act BR CMCD Dep FACS IF IP IHC WB PE Rat IgG2b kappa Log in to see A161A1 5

Top referenced anti-CD4 antibody for Complement Mediated Cell Depletion

Similar anti-CD4 Antibodies

Application / Reactivity Human
Activation (Act) 3 Antibodies
Biochemical Assay (BCA) 6 Antibodies
Blocking Antibody (Inhibition) 1 Antibodies
Blocking Reagent (BR) 9 Antibodies
Complement Mediated Cell Depletion (CMCD) 2 Antibodies
Depletion (Dep) 4 Antibodies
ELISA 239 Antibodies
ELISA (Capture) 1 Antibodies
ELISA (Detection) 1 Antibodies
ELISpot (Detection) (ELISPOT (Detection)) 1 Antibodies
Enzyme Immunoassay (EIA) 6 Antibodies
Flow Cytometry (FACS) 694 Antibodies
Functional Studies (Func) 31 Antibodies
Immunochromatography (IC) 3 Antibodies
Immunocytochemistry (ICC) 38 Antibodies
Immunofluorescence (IF) 92 Antibodies

General

Antigen CD4 Molecule (CD4) Antibodies
Reactivity Human
(1067), (630), (221), (61), (44), (43), (23), (22), (21), (19), (18), (15), (13), (9), (8), (7), (7), (6), (5), (5), (4), (3), (2), (2), (2), (2), (1), (1)
Host Rat
(1240), (588), (236), (4), (2), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This CD4 antibody is conjugated to PE
(267), (230), (164), (114), (39), (36), (36), (33), (31), (30), (26), (24), (21), (17), (16), (15), (13), (12), (11), (11), (11), (10), (10), (10), (10), (10), (9), (8), (8), (7), (5), (5), (5), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Activation (Act), Blocking Reagent (BR), Complement Mediated Cell Depletion (CMCD), Depletion (Dep), Flow Cytometry (FACS), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
(1575), (393), (362), (299), (286), (255), (158), (91), (83), (69), (33), (28), (26), (18), (14), (11), (10), (9), (7), (7), (6), (6), (5), (5), (5), (4), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Pubmed 5 references available
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Product Details anti-CD4 Antibody

Target Details CD4 Application Details Handling References for anti-CD4 Antibody (ABIN2662640) Images
Purification The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
Clone A161A1
Isotype IgG2b kappa

Target Details CD4

Product Details anti-CD4 Antibody Application Details Handling References for anti-CD4 Antibody (ABIN2662640) Images back to top
Antigen
Alternative Name CD4 (CD4 Antibody Abstract)
Background CD4, also known as T4/Leu-3, is a 55 kD single-chain type I transmembrane glycoprotein and member of the immunoglobulin superfamily. It is expressed on most thymocytes, helper T cells, type II NKT cells, and monocytes/macrophages. CD4 is part of the TCR/CD3 complex, binds to β2 domain from the MHC class II molecule, and participates in TCR signal transduction. CD4 is the receptor of IL-16 and is a coreceptor for the human immunodeficiency virus (HIV) and human herpes virus 7 (HHV-7).
Research Area Immunology, Adaptive Immunity, Hematopoietic Progenitors, CD Antigens, Surface Receptors of Immune Cells
Pathways TCR Signaling

Application Details

Product Details anti-CD4 Antibody Target Details CD4 Handling References for anti-CD4 Antibody (ABIN2662640) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-CD4 Antibody Target Details CD4 Application Details References for anti-CD4 Antibody (ABIN2662640) Images back to top
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Protect from prolonged exposure to light. Do not freeze.
Storage 4 °C
Storage Comment The antibody solution should be stored undiluted between 2°C and 8°C.

References for anti-CD4 Antibody (ABIN2662640)

Product Details anti-CD4 Antibody Target Details CD4 Application Details Handling Images back to top
Background publications

Zhu, Yamane, Paul: "Differentiation of effector CD4 T cell populations (*)." in: Annual review of immunology, Vol. 28, pp. 445-89, 2010

Vignali: "CD4 on the road to coreceptor status." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 184, Issue 11, pp. 5933-4, 2010

Zhou, Chong, Littman: "Plasticity of CD4+ T cell lineage differentiation." in: Immunity, Vol. 30, Issue 5, pp. 646-55, 2009

Singer, Adoro, Park: "Lineage fate and intense debate: myths, models and mechanisms of CD4- versus CD8-lineage choice." in: Nature reviews. Immunology, Vol. 8, Issue 10, pp. 788-801, 2008

Zhu, Paul: "CD4 T cells: fates, functions, and faults." in: Blood, Vol. 112, Issue 5, pp. 1557-69, 2008

Images

Product Details anti-CD4 Antibody Target Details CD4 Application Details Handling References for anti-CD4 Antibody (ABIN2662640) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-CD4 antibody (CD4 Molecule)  (PE) (ABIN2662640) anti-CD4 Molecule (CD4) antibody (PE)