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anti-Human CD4 antibody for Depletion

Recommended CD4 Antibody (supplied by: Log in to see )

Antigen
CD4 Molecule (CD4) Antibodies
  • cd4
  • CD4mut
  • L3T4
  • Ly-4
  • p55
  • W3/25
Reactivity
Human
1197
694
240
69
52
45
25
23
22
21
19
15
14
12
9
8
7
7
7
7
6
5
5
5
3
2
2
2
1
1
1
Host
Rat
1362
666
276
4
2
1
Clonality
Monoclonal
Conjugate
This CD4 antibody is conjugated to PE
284
238
176
114
44
42
42
39
39
38
36
32
26
24
22
22
21
20
19
19
19
19
19
16
15
13
9
8
8
8
7
7
5
5
4
4
4
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Application
Activation (Act), Blocking Reagent (BR), Complement Mediated Cell Depletion (CMCD), Depletion (Dep), Flow Cytometry (FACS), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
1808
435
398
356
309
299
178
136
100
70
33
28
28
26
22
18
14
11
10
9
7
6
6
5
5
5
4
2
2
2
2
2
2
1
1
1
1
1
1
1
1
Supplier
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Available images

Catalog No. ABIN2662640
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008709465 ABIN2663436 BR Dep FACS CyTOF IHC PE Mouse IgG1 kappa Log in to see SK3 5
0.0008709465 ABIN2662641 Act BR CMCD Dep FACS IF IP IHC WB PE Rat IgG2b kappa Log in to see A161A1 5
0.0008709465 ABIN2663437 BR Dep FACS CyTOF IHC PE Mouse IgG1 kappa Log in to see SK3 5

Top referenced anti-CD4 antibody for Depletion

Similar anti-CD4 Antibodies

Application / Reactivity Human
Activation (Act) 3 Antibodies
Biochemical Assay (BCA) 6 Antibodies
Blocking Antibody (Inhibition) 1 Antibodies
Blocking Reagent (BR) 9 Antibodies
Complement Mediated Cell Depletion (CMCD) 2 Antibodies
Depletion (Dep) 4 Antibodies
ELISA 249 Antibodies
ELISA (Capture) 1 Antibodies
ELISA (Detection) 1 Antibodies
ELISpot (Detection) (ELISPOT (Detection)) 1 Antibodies
Enzyme Immunoassay (EIA) 6 Antibodies
Flow Cytometry (FACS) 817 Antibodies
Functional Studies (Func) 32 Antibodies
Immunochromatography (IC) 3 Antibodies
Immunocytochemistry (ICC) 43 Antibodies

General

Antigen CD4 Molecule (CD4) Antibodies
Reactivity Human
(1197), (694), (240), (69), (52), (45), (25), (23), (22), (21), (19), (15), (14), (12), (9), (8), (7), (7), (7), (7), (6), (5), (5), (5), (3), (2), (2), (2), (1), (1), (1)
Host Rat
(1362), (666), (276), (4), (2), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This CD4 antibody is conjugated to PE
(284), (238), (176), (114), (44), (42), (42), (39), (39), (38), (36), (32), (26), (24), (22), (22), (21), (20), (19), (19), (19), (19), (19), (16), (15), (13), (9), (8), (8), (8), (7), (7), (5), (5), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Activation (Act), Blocking Reagent (BR), Complement Mediated Cell Depletion (CMCD), Depletion (Dep), Flow Cytometry (FACS), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
(1808), (435), (398), (356), (309), (299), (178), (136), (100), (70), (33), (28), (28), (26), (22), (18), (14), (11), (10), (9), (7), (6), (6), (5), (5), (5), (4), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Pubmed 5 references available
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Product Details anti-CD4 Antibody

Target Details CD4 Application Details Handling References for anti-CD4 Antibody (ABIN2662640) Images
Purification The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
Clone A161A1
Isotype IgG2b kappa

Target Details CD4

Product Details anti-CD4 Antibody Application Details Handling References for anti-CD4 Antibody (ABIN2662640) Images back to top
Antigen
Alternative Name CD4 (CD4 Antibody Abstract)
Background CD4, also known as T4/Leu-3, is a 55 kD single-chain type I transmembrane glycoprotein and member of the immunoglobulin superfamily. It is expressed on most thymocytes, helper T cells, type II NKT cells, and monocytes/macrophages. CD4 is part of the TCR/CD3 complex, binds to β2 domain from the MHC class II molecule, and participates in TCR signal transduction. CD4 is the receptor of IL-16 and is a coreceptor for the human immunodeficiency virus (HIV) and human herpes virus 7 (HHV-7).
Research Area Immunology, Adaptive Immunity, Hematopoietic Progenitors, CD Antigens, Surface Receptors of Immune Cells
Pathways TCR Signaling

Application Details

Product Details anti-CD4 Antibody Target Details CD4 Handling References for anti-CD4 Antibody (ABIN2662640) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-CD4 Antibody Target Details CD4 Application Details References for anti-CD4 Antibody (ABIN2662640) Images back to top
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Protect from prolonged exposure to light. Do not freeze.
Storage 4 °C
Storage Comment The antibody solution should be stored undiluted between 2°C and 8°C.

References for anti-CD4 Antibody (ABIN2662640)

Product Details anti-CD4 Antibody Target Details CD4 Application Details Handling Images back to top
Background publications

Zhu, Yamane, Paul: "Differentiation of effector CD4 T cell populations (*)." in: Annual review of immunology, Vol. 28, pp. 445-89, 2010

Vignali: "CD4 on the road to coreceptor status." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 184, Issue 11, pp. 5933-4, 2010

Zhou, Chong, Littman: "Plasticity of CD4+ T cell lineage differentiation." in: Immunity, Vol. 30, Issue 5, pp. 646-55, 2009

Singer, Adoro, Park: "Lineage fate and intense debate: myths, models and mechanisms of CD4- versus CD8-lineage choice." in: Nature reviews. Immunology, Vol. 8, Issue 10, pp. 788-801, 2008

Zhu, Paul: "CD4 T cells: fates, functions, and faults." in: Blood, Vol. 112, Issue 5, pp. 1557-69, 2008

Images

Product Details anti-CD4 Antibody Target Details CD4 Application Details Handling References for anti-CD4 Antibody (ABIN2662640) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-CD4 antibody (CD4 Molecule)  (PE) (ABIN2662640) anti-CD4 Molecule (CD4) antibody (PE)