You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Human CD4 antibody for Intracellular Flow Cytometry

Recommended CD4 Antibody (supplied by: Log in to see )

Antigen
CD4 Molecule (CD4) Antibodies
  • cd4
  • CD4mut
  • L3T4
  • Ly-4
  • p55
  • W3/25
Reactivity
Human
1197
695
241
72
53
45
25
23
22
21
19
15
15
15
10
9
8
7
7
7
6
5
5
5
3
2
2
2
1
1
1
Host
Mouse
1371
670
268
4
2
1
Clonality
Monoclonal
Conjugate
This CD4 antibody is conjugated to Biotin
286
239
177
113
44
43
42
39
39
38
35
33
26
24
22
22
21
20
19
19
19
19
19
16
15
13
9
8
8
8
7
6
5
5
4
4
4
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Application
Intracellular Flow Cytometry (ICFC), ELISA, Western Blotting (WB)
1816
434
400
366
307
302
181
141
104
70
33
29
28
27
23
17
14
11
10
9
7
6
6
6
5
5
4
3
2
2
2
2
2
2
2
1
1
1
1
1
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

It's quick and easy to submit your validation proposal. I want to validate this product

Learn more

Available images

Catalog No. ABIN2661075
Contact our Customer Service for availability and price in your country.
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008656421 ABIN2661070 ELISA (Detection) ELISPOT (Detection) ICFC Biotin Mouse IgG1 kappa Log in to see RPA-T4 9
0.0008656421 ABIN2658654 FACS ICFC APC Mouse IgG2b kappa Log in to see OKT4 8
0.0008656421 ABIN2659623 ICFC WB PE-Cy7 Mouse IgG1 kappa Log in to see RPA-T4 10
0.0008656421 ABIN2661069 ICFC Biotin Mouse IgG1 kappa Log in to see SK3 5
0.0008656421 ABIN2662087 Func ICC FACS IF ICFC IP WB Pacific Blue Mouse IgG2b kappa Log in to see OKT4 8
0.0008656421 ABIN2662088 Func ICC FACS IF ICFC IP WB Pacific Blue Mouse IgG2b kappa Log in to see OKT4 8
0.0008656421 ABIN2661076 ICFC ELISA WB Biotin Mouse IgG2b kappa Log in to see OKT4 8
0.0008656421 ABIN2658655 FACS ICFC APC Mouse IgG2b kappa Log in to see OKT4 9
0.0008656421 ABIN2659624 ICFC WB PE-Cy7 Mouse IgG1 kappa Log in to see RPA-T4 10

Top referenced anti-CD4 antibody for Intracellular Flow Cytometry

Similar anti-CD4 Antibodies

Application / Reactivity Human
Activation (Act) 3 Antibodies
Biochemical Assay (BCA) 6 Antibodies
Blocking Antibody (Inhibition) 1 Antibodies
Blocking Reagent (BR) 9 Antibodies
Complement Mediated Cell Depletion (CMCD) 2 Antibodies
Depletion (Dep) 4 Antibodies
ELISA 243 Antibodies
ELISA (Capture) 1 Antibodies
ELISA (Detection) 1 Antibodies
ELISpot (Detection) (ELISPOT (Detection)) 1 Antibodies
Enzyme Immunoassay (EIA) 6 Antibodies
Flow Cytometry (FACS) 819 Antibodies
Functional Studies (Func) 32 Antibodies
Immunochromatography (IC) 3 Antibodies
Immunocytochemistry (ICC) 47 Antibodies

General

Antigen CD4 Molecule (CD4) Antibodies
Reactivity Human
(1197), (695), (241), (72), (53), (45), (25), (23), (22), (21), (19), (15), (15), (15), (10), (9), (8), (7), (7), (7), (6), (5), (5), (5), (3), (2), (2), (2), (1), (1), (1)
Host Mouse
(1371), (670), (268), (4), (2), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This CD4 antibody is conjugated to Biotin
(286), (239), (177), (113), (44), (43), (42), (39), (39), (38), (35), (33), (26), (24), (22), (22), (21), (20), (19), (19), (19), (19), (19), (16), (15), (13), (9), (8), (8), (8), (7), (6), (5), (5), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Intracellular Flow Cytometry (ICFC), ELISA, Western Blotting (WB)
(1816), (434), (400), (366), (307), (302), (181), (141), (104), (70), (33), (29), (28), (27), (23), (17), (14), (11), (10), (9), (7), (6), (6), (6), (5), (5), (4), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Pubmed 8 references available
Supplier Log in to see

Product Details anti-CD4 Antibody

Target Details CD4 Application Details Handling References for anti-CD4 Antibody (ABIN2661075) Images
Cross-Reactivity Chimpanzee, Cynomolgus, Rhesus Monkey
Purification The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.
Clone OKT4
Isotype IgG2b kappa

Target Details CD4

Product Details anti-CD4 Antibody Application Details Handling References for anti-CD4 Antibody (ABIN2661075) Images back to top
Antigen
Alternative Name CD4 (CD4 Antibody Abstract)
Background CD4, also known as T4, is a 55 kD single-chain type I transmembrane glycoprotein expressed on most thymocytes, a subset of T cells, and monocytes/macrophages. CD4, a member of the Ig superfamily, recognizes antigens associated with MHC class II molecules and participates in cell-cell interactions, thymic differentiation, and signal transduction. CD4 acts as a primary receptor for HIV, binding to HIV gp120. CD4 has also been shown to interact with IL-16.
Research Area Immunology, Adaptive Immunity, Hematopoietic Progenitors, CD Antigens, Surface Receptors of Immune Cells
Pathways TCR Signaling

Application Details

Product Details anti-CD4 Antibody Target Details CD4 Handling References for anti-CD4 Antibody (ABIN2661075) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-CD4 Antibody Target Details CD4 Application Details References for anti-CD4 Antibody (ABIN2661075) Images back to top
Concentration 0.5 mg/mL
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Do not freeze.
Storage 4 °C
Storage Comment The antibody solution should be stored undiluted between 2°C and 8°C.

References for anti-CD4 Antibody (ABIN2661075)

Product Details anti-CD4 Antibody Target Details CD4 Application Details Handling Images back to top
Background publications

Liu, Yang, Wiehe, Nicely, Vandergrift, Rountree, Bonsignori, Alam, Gao, Haynes, Kelsoe: "Polyreactivity and autoreactivity among HIV-1 antibodies." in: Journal of virology, Vol. 89, Issue 1, pp. 784-98, 2014

Cicin-Sain, Smyk-Pearson, Smyk-Paerson, Currier, Byrd, Koudelka, Robinson, Swarbrick, Tackitt, Legasse, Fischer, Nikolich-Zugich, Park, Hobbs, Doane, Mori, Axthelm, Axthelm, Lewinsohn, Nikolich-Zugich: "Loss of naive T cells and repertoire constriction predict poor response to vaccination in old primates." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 184, Issue 12, pp. 6739-45, 2010

Kmieciak, Gowda, Graham, Godder, Bear, Marincola, Manjili: "Human T cells express CD25 and Foxp3 upon activation and exhibit effector/memory phenotypes without any regulatory/suppressor function." in: Journal of translational medicine, Vol. 7, pp. 89, 2009

Rosenzweig, Marks, DeMaria, Connole, Johnson: "Identification of primitive hematopoietic progenitor cells in the rhesus macaque." in: Journal of medical primatology, Vol. 30, Issue 1, pp. 36-45, 2001

Boche, Khatissian, Gray, Falanga, Montagnier, Hurtrel: "Viral load and neuropathology in the SIV model." in: Journal of neurovirology, Vol. 5, Issue 3, pp. 232-40, 1999

Center, Kornfeld, Cruikshank: "Interleukin 16 and its function as a CD4 ligand." in: Immunology today, Vol. 17, Issue 10, pp. 476-81, 1997

Gaubin, Autiero, Houlgatte, Basmaciogullari, Auffray, Piatier-Tonneau: "Molecular basis of T lymphocyte CD4 antigen functions." in: European journal of clinical chemistry and clinical biochemistry : journal of the Forum of European Clinical Chemistry Societies, Vol. 34, Issue 9, pp. 723-8, 1997

Reinherz, Kung, Goldstein, Schlossman: "Separation of functional subsets of human T cells by a monoclonal antibody." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 76, Issue 8, pp. 4061-5, 1979

Images

Product Details anti-CD4 Antibody Target Details CD4 Application Details Handling References for anti-CD4 Antibody (ABIN2661075) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-CD4 antibody (CD4 Molecule)  (Biotin) (ABIN2661075) anti-CD4 Molecule (CD4) antibody (Biotin)