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anti-Human CD4 antibody for Intracellular Flow Cytometry

Recommended CD4 Antibody (supplied by: Log in to see )

Antigen
CD4 Molecule (CD4) Antibodies
  • cd4
  • CD4mut
  • L3T4
  • Ly-4
  • p55
  • W3/25
Reactivity
Human
1163
655
241
72
56
41
26
23
22
21
19
15
15
15
11
10
9
8
7
7
6
5
5
5
3
2
2
2
1
1
1
Host
Mouse
1329
624
273
8
4
1
Clonality
Monoclonal
Conjugate
This CD4 antibody is conjugated to Biotin
274
237
169
106
45
44
42
35
35
35
33
33
24
22
21
20
20
18
17
17
17
17
16
15
15
13
13
8
8
7
7
7
6
4
4
4
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
Application
ELISA (Detection), ELISpot (Detection) (ELISPOT (Detection)), Intracellular Flow Cytometry (ICFC)
1743
424
400
334
304
299
181
139
115
68
37
28
28
27
22
17
14
14
11
9
7
6
6
6
5
4
3
2
2
2
2
2
2
2
1
1
1
1
Supplier
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Catalog No. ABIN2661070
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.00087262125 ABIN2661075 ICFC ELISA WB Biotin Mouse IgG2b kappa Log in to see OKT4 8
0.00087262125 ABIN2661069 ICFC Biotin Mouse IgG1 kappa Log in to see SK3 5
0.00087262125 ABIN2659623 ICFC WB PE-Cy7 Mouse IgG1 kappa Log in to see RPA-T4 10
0.00087262125 ABIN2658654 FACS ICFC APC Mouse IgG2b kappa Log in to see OKT4 8
0.00087262125 ABIN2661076 ICFC ELISA WB Biotin Mouse IgG2b kappa Log in to see OKT4 8
0.00087262125 ABIN2662087 Func ICC FACS IF ICFC IP WB Pacific Blue Mouse IgG2b kappa Log in to see OKT4 8
0.00087262125 ABIN2662088 Func ICC FACS IF ICFC IP WB Pacific Blue Mouse IgG2b kappa Log in to see OKT4 8
0.00087262125 ABIN2659624 ICFC WB PE-Cy7 Mouse IgG1 kappa Log in to see RPA-T4 10
0.00087262125 ABIN2658655 FACS ICFC APC Mouse IgG2b kappa Log in to see OKT4 9

Top referenced anti-CD4 antibody for Intracellular Flow Cytometry

Similar anti-CD4 Antibodies

Application / Reactivity Human
Activation (Act) 3 Antibodies
Biochemical Assay (BCA) 6 Antibodies
Blocking Antibody (Inhibition) 1 Antibodies
Blocking Peptide (BP) 19 Antibodies
Blocking Reagent (BR) 9 Antibodies
Complement Mediated Cell Depletion (CMCD) 2 Antibodies
Depletion (Dep) 4 Antibodies
ELISA 244 Antibodies
ELISA (Capture) 1 Antibodies
ELISA (Detection) 1 Antibodies
ELISpot (Detection) (ELISPOT (Detection)) 1 Antibodies
Enzyme Immunoassay (EIA) 6 Antibodies
Flow Cytometry (FACS) 784 Antibodies
Functional Studies (Func) 30 Antibodies
Immunochromatography (IC) 3 Antibodies
Immunocytochemistry (ICC) 51 Antibodies

General

Antigen CD4 Molecule (CD4) Antibodies
Reactivity Human
(1163), (655), (241), (72), (56), (41), (26), (23), (22), (21), (19), (15), (15), (15), (11), (10), (9), (8), (7), (7), (6), (5), (5), (5), (3), (2), (2), (2), (1), (1), (1)
Host Mouse
(1329), (624), (273), (8), (4), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This CD4 antibody is conjugated to Biotin
(274), (237), (169), (106), (45), (44), (42), (35), (35), (35), (33), (33), (24), (22), (21), (20), (20), (18), (17), (17), (17), (17), (16), (15), (15), (13), (13), (8), (8), (7), (7), (7), (6), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Application ELISA (Detection), ELISpot (Detection) (ELISPOT (Detection)), Intracellular Flow Cytometry (ICFC)
(1743), (424), (400), (334), (304), (299), (181), (139), (115), (68), (37), (28), (28), (27), (22), (17), (14), (14), (11), (9), (7), (6), (6), (6), (5), (4), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Pubmed 9 references available
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Product Details anti-CD4 Antibody

Target Details CD4 Application Details Handling References for anti-CD4 Antibody (ABIN2661070) Images
Cross-Reactivity Chimpanzee
Purification The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.
Clone RPA-T4
Isotype IgG1 kappa

Target Details CD4

Product Details anti-CD4 Antibody Application Details Handling References for anti-CD4 Antibody (ABIN2661070) Images back to top
Antigen
Alternative Name CD4 (CD4 Antibody Abstract)
Background CD4, also known as T4, is a 55 kD single-chain type I transmembrane glycoprotein expressed on most thymocytes, a subset of T cells, and monocytes/macrophages. CD4, a member of the Ig superfamily, recognizes antigens associated with MHC class II molecules, and participates in cell-cell interactions, thymic differentiation, and signal transduction. CD4 acts as a primary receptor for HIV, binding to HIV gp120. CD4 has also been shown to interact with IL-16.
Research Area Immunology, Adaptive Immunity, Hematopoietic Progenitors, CD Antigens, Surface Receptors of Immune Cells
Pathways TCR Signaling

Application Details

Product Details anti-CD4 Antibody Target Details CD4 Handling References for anti-CD4 Antibody (ABIN2661070) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-CD4 Antibody Target Details CD4 Application Details References for anti-CD4 Antibody (ABIN2661070) Images back to top
Concentration 0.5 mg/mL
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Do not freeze.
Storage 4 °C
Storage Comment The antibody solution should be stored undiluted between 2°C and 8°C.

References for anti-CD4 Antibody (ABIN2661070)

Product Details anti-CD4 Antibody Target Details CD4 Application Details Handling Images back to top
Background publications

Zenaro, Donini, Dusi: "Induction of Th1/Th17 immune response by Mycobacterium tuberculosis: role of dectin-1, Mannose Receptor, and DC-SIGN." in: Journal of leukocyte biology, Vol. 86, Issue 6, pp. 1393-401, 2009

Lan, Cheng, Lian, Tsuneyama, Yang, Moritoki, Chuang, Nakamura, Saito, Shimoda, Tanaka, Bowlus, Takano, Ansari, Coppel, Gershwin: "Liver-targeted and peripheral blood alterations of regulatory T cells in primary biliary cirrhosis." in: Hepatology (Baltimore, Md.), Vol. 43, Issue 4, pp. 729-37, 2006

Mack, Tucker, Sokol, Karrer, Kotzin, Whitington, Miller: "Biliary atresia is associated with CD4+ Th1 cell-mediated portal tract inflammation." in: Pediatric research, Vol. 56, Issue 1, pp. 79-87, 2004

Yoshino, Ami, Terao, Tashiro, Honda: "Upgrading of flow cytometric analysis for absolute counts, cytokines and other antigenic molecules of cynomolgus monkeys (Macaca fascicularis) by using anti-human cross-reactive antibodies." in: Experimental animals / Japanese Association for Laboratory Animal Science, Vol. 49, Issue 2, pp. 97-110, 2000

Friedman, Shimizu, Smith, Colvin, Seebach, Sachs, Iacomini: "Human CD4+ T cells mediate rejection of porcine xenografts." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 162, Issue 9, pp. 5256-62, 1999

Moir, Lapointe, Malaspina, Ostrowski, Cole, Chun, Adelsberger, Baseler, Hwu, Fauci et al.: "CD40-Mediated induction of CD4 and CXCR4 on B lymphocytes correlates with restricted susceptibility to human immunodeficiency virus type 1 infection: potential role of B lymphocytes as a viral ..." in: Journal of virology, Vol. 73, Issue 10, pp. 7972-80, 1999

Center, Kornfeld, Cruikshank: "Interleukin 16 and its function as a CD4 ligand." in: Immunology today, Vol. 17, Issue 10, pp. 476-81, 1997

Gaubin, Autiero, Houlgatte, Basmaciogullari, Auffray, Piatier-Tonneau: "Molecular basis of T lymphocyte CD4 antigen functions." in: European journal of clinical chemistry and clinical biochemistry : journal of the Forum of European Clinical Chemistry Societies, Vol. 34, Issue 9, pp. 723-8, 1997

Deng, Bell, Huie, Pinto, Hunt, Stinson, Sibley, Hall, Valantine: "Cardiac allograft vascular disease. Relationship to microvascular cell surface markers and inflammatory cell phenotypes on endomyocardial biopsy." in: Circulation, Vol. 91, Issue 6, pp. 1647-54, 1995

Images

Product Details anti-CD4 Antibody Target Details CD4 Application Details Handling References for anti-CD4 Antibody (ABIN2661070) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-CD4 antibody (CD4 Molecule)  (Biotin) (ABIN2661070) anti-CD4 Molecule (CD4) antibody (Biotin)