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anti-Human CD4 antibody for Immunostaining

Recommended CD4 Antibody (supplied by: Log in to see )

Antigen
CD4 Molecule (CD4) Antibodies
  • cd4
  • L3T4
  • Ly-4
  • CD4mut
  • W3/25
  • p55
  • CD4 molecule
  • CD4 antigen
  • T-cell surface glycoprotein CD4
  • Cd4 molecule
  • CD4
  • cd4
  • Cd4
Reactivity
Human
1188
667
252
72
61
43
34
24
22
22
19
17
16
15
11
11
10
10
9
7
6
6
5
5
4
2
2
2
1
1
1
1
Host
Mouse
1358
627
272
9
4
1
Clonality
Monoclonal
Conjugate
This CD4 antibody is un-conjugated
281
239
171
106
47
45
43
36
36
35
34
32
25
25
21
21
20
19
18
18
18
18
16
15
13
13
12
10
8
8
7
6
6
6
5
4
4
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
Application
Activation (Act), Blocking Antibody (Inhibition), Immunostaining (ISt)
1755
468
442
330
314
298
151
150
85
61
39
38
30
29
29
22
19
18
14
14
11
9
7
6
6
6
5
4
3
2
2
2
2
2
2
2
1
1
1
1
1
1
Supplier
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Catalog No. ABIN1002085
$ 385.77
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Application / Reactivity Human
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ELISA 251 Antibodies
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General

Antigen CD4 Molecule (CD4) Antibodies
Reactivity Human
(1188), (667), (252), (72), (61), (43), (34), (24), (22), (22), (19), (17), (16), (15), (11), (11), (10), (10), (9), (7), (6), (6), (5), (5), (4), (2), (2), (2), (1), (1), (1), (1)
Host Mouse
(1358), (627), (272), (9), (4), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This CD4 antibody is un-conjugated
(281), (239), (171), (106), (47), (45), (43), (36), (36), (35), (34), (32), (25), (25), (21), (21), (20), (19), (18), (18), (18), (18), (16), (15), (13), (13), (12), (10), (8), (8), (7), (6), (6), (6), (5), (4), (4), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Application Activation (Act), Blocking Antibody (Inhibition), Immunostaining (ISt)
(1755), (468), (442), (330), (314), (298), (151), (150), (85), (61), (39), (38), (30), (29), (29), (22), (19), (18), (14), (14), (11), (9), (7), (6), (6), (6), (5), (4), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
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Product Details anti-CD4 Antibody

Target Details CD4 Application Details Handling Images
Predicted Reactivity Human CD4
Purification Ion exchange chromatography
Immunogen Purified human PBL CD4+ T cells
Clone HCD4
Isotype IgG2b

Target Details CD4

Product Details anti-CD4 Antibody Application Details Handling Images back to top
Antigen
Alternative Name CD4 (CD4 Antibody Abstract)
Background In humans, CD4 is expressed on the surface of peripheral T-cells, thymocytes, on macrophages and granulocytes. It acts as a cellular adhesion molecule binding MHC class 2 molecules. Moreover, CD4 also acts as a receptor for HIV but requires cosignals. CD4 expression in brain suggests that it may play a more general role in mediating cell recognition events than merely those of cellular immune responses. CD4(+) cells are T-helper cells which, upon cell activation, produce a number of different cytokines and play a role in the activation and/or proliferation of B-cells, cytotoxic T-lymphocytes, and macrophages. Thymocytes which are CD4(+) and CD8(-) produce factors such as IL4, IL5, IL10 and IFN-gamma. CD4 is a 55 kDa transmembrane glycoprotein belonging to the immunoglobulin superfamily.
Research Area Immunology, Adaptive Immunity, Hematopoietic Progenitors, CD Antigens, Surface Receptors of Immune Cells
Pathways TCR Signaling

Application Details

Product Details anti-CD4 Antibody Target Details CD4 Handling Images back to top
Application Notes Blocking, staining and activating antibody. Blocks blinding of HIV to CD4. For staining, use 10 µl/10⁶ cells. Titer for blocking and activating T cells should be determined individually by the investigator. Antibody might also be suited for other applications not tested so far.
Restrictions For Research Use only

Handling

Product Details anti-CD4 Antibody Target Details CD4 Application Details Images back to top
Format Lyophilized
Buffer NA
Handling Advice Please Note: Always centrifuge product briefly before opening vial. Reconstitute with 0.5 ml sterile H20 or PBS to give a 1 mg/ml concentration. Mix gently, wash the sides of the vial and wait 30-60 seconds before use. Protein concentration: 1 mg/ml (after reconstitution).
Storage 4 °C/-20 °C