anti-Human CD4 antibody for Immunostaining

Recommended CD4 Antibody (supplied by: Log in to see )

Antigen
CD4 Molecule (CD4) Antibodies
  • cd4
  • L3T4
  • Ly-4
  • CD4mut
  • W3/25
  • p55
  • CD4 molecule
  • CD4 antigen
  • T-cell surface glycoprotein CD4
  • Cd4 molecule
  • CD4
  • cd4
  • Cd4
Reactivity
Human
1219
632
234
68
67
40
36
27
26
22
21
19
18
16
15
15
13
10
10
9
7
6
5
5
5
4
4
3
3
3
3
2
2
2
2
2
1
1
1
1
Host
Mouse
1376
587
281
11
4
1
1
1
Clonality
Monoclonal
Conjugate
This CD4 antibody is un-conjugated
266
227
170
103
49
48
46
40
36
34
34
30
27
25
21
21
19
19
18
18
18
18
16
15
15
13
13
13
11
9
9
8
6
5
5
4
4
4
4
3
3
3
3
3
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Application
Activation (Act), Blocking Antibody (Inhibition), Immunostaining (ISt)
1744
490
445
353
323
309
157
155
88
78
39
38
31
30
30
25
18
14
14
11
9
9
6
6
5
4
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
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Catalog No. ABIN1002085
$ 385.77
Plus shipping costs $45.00

General

Antigen CD4 Molecule (CD4) Antibodies
Reactivity Human
(1219), (632), (234), (68), (67), (40), (36), (27), (26), (22), (21), (19), (18), (16), (15), (15), (13), (10), (10), (9), (7), (6), (5), (5), (5), (4), (4), (3), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Host Mouse
(1376), (587), (281), (11), (4), (1), (1), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This CD4 antibody is un-conjugated
(266), (227), (170), (103), (49), (48), (46), (40), (36), (34), (34), (30), (27), (25), (21), (21), (19), (19), (18), (18), (18), (18), (16), (15), (15), (13), (13), (13), (11), (9), (9), (8), (6), (5), (5), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Activation (Act), Blocking Antibody (Inhibition), Immunostaining (ISt)
(1744), (490), (445), (353), (323), (309), (157), (155), (88), (78), (39), (38), (31), (30), (30), (25), (18), (14), (14), (11), (9), (9), (6), (6), (5), (4), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
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Product Details anti-CD4 Antibody

Target Details CD4 Application Details Handling Images
Predicted Reactivity Human CD4
Purification Ion exchange chromatography
Immunogen Purified human PBL CD4+ T cells
Clone HCD4
Isotype IgG2b

Target Details CD4

Product Details anti-CD4 Antibody Application Details Handling Images back to top
Antigen
Alternative Name CD4 (CD4 Antibody Abstract)
Background In humans, CD4 is expressed on the surface of peripheral T-cells, thymocytes, on macrophages and granulocytes. It acts as a cellular adhesion molecule binding MHC class 2 molecules. Moreover, CD4 also acts as a receptor for HIV but requires cosignals. CD4 expression in brain suggests that it may play a more general role in mediating cell recognition events than merely those of cellular immune responses. CD4(+) cells are T-helper cells which, upon cell activation, produce a number of different cytokines and play a role in the activation and/or proliferation of B-cells, cytotoxic T-lymphocytes, and macrophages. Thymocytes which are CD4(+) and CD8(-) produce factors such as IL4, IL5, IL10 and IFN-gamma. CD4 is a 55 kDa transmembrane glycoprotein belonging to the immunoglobulin superfamily.
Research Area Immunology, Adaptive Immunity, Hematopoietic Progenitors, CD Antigens, Surface Receptors of Immune Cells
Pathways TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events

Application Details

Product Details anti-CD4 Antibody Target Details CD4 Handling Images back to top
Application Notes Blocking, staining and activating antibody. Blocks blinding of HIV to CD4. For staining, use 10 µl/10⁶ cells. Titer for blocking and activating T cells should be determined individually by the investigator. Antibody might also be suited for other applications not tested so far.
Restrictions For Research Use only

Handling

Product Details anti-CD4 Antibody Target Details CD4 Application Details Images back to top
Format Lyophilized
Buffer NA
Handling Advice Please Note: Always centrifuge product briefly before opening vial. Reconstitute with 0.5 ml sterile H20 or PBS to give a 1 mg/ml concentration. Mix gently, wash the sides of the vial and wait 30-60 seconds before use. Protein concentration: 1 mg/ml (after reconstitution).
Storage 4 °C/-20 °C