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anti-Human CD4 antibody for Immunostaining

Recommended CD4 Antibody (supplied by: Log in to see )

Antigen
CD4 Molecule (CD4) Antibodies
  • cd4
  • CD4mut
  • L3T4
  • Ly-4
  • p55
  • W3/25
Reactivity
Human
1163
655
241
72
56
41
26
23
22
21
19
15
15
15
11
10
9
8
7
7
6
5
5
5
3
2
2
2
1
1
1
Host
Mouse
1329
624
273
8
4
1
Clonality
Monoclonal
Conjugate
This CD4 antibody is un-conjugated
274
237
170
106
45
44
42
35
35
35
33
33
24
22
21
20
20
18
17
17
17
17
16
15
15
13
13
8
8
7
7
7
6
4
4
4
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
Application
Activation (Act), Blocking Antibody (Inhibition), Immunostaining (ISt)
1743
424
400
334
304
299
181
139
115
68
37
28
28
27
22
18
14
14
11
9
7
6
6
6
5
4
2
2
2
2
2
2
2
1
1
1
1
1
1
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Catalog No. ABIN1002085
$ 385.77
Plus shipping costs $45.00

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Application / Reactivity Human
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Complement Mediated Cell Depletion (CMCD) 2 Antibodies
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General

Antigen CD4 Molecule (CD4) Antibodies
Reactivity Human
(1163), (655), (241), (72), (56), (41), (26), (23), (22), (21), (19), (15), (15), (15), (11), (10), (9), (8), (7), (7), (6), (5), (5), (5), (3), (2), (2), (2), (1), (1), (1)
Host Mouse
(1329), (624), (273), (8), (4), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This CD4 antibody is un-conjugated
(274), (237), (170), (106), (45), (44), (42), (35), (35), (35), (33), (33), (24), (22), (21), (20), (20), (18), (17), (17), (17), (17), (16), (15), (15), (13), (13), (8), (8), (7), (7), (7), (6), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Application Activation (Act), Blocking Antibody (Inhibition), Immunostaining (ISt)
(1743), (424), (400), (334), (304), (299), (181), (139), (115), (68), (37), (28), (28), (27), (22), (18), (14), (14), (11), (9), (7), (6), (6), (6), (5), (4), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
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Product Details anti-CD4 Antibody

Target Details CD4 Application Details Handling Images
Predicted Reactivity Human CD4
Purification Ion exchange chromatography
Immunogen Purified human PBL CD4+ T cells
Clone HCD4
Isotype IgG2b

Target Details CD4

Product Details anti-CD4 Antibody Application Details Handling Images back to top
Antigen
Alternative Name CD4 (CD4 Antibody Abstract)
Background In humans, CD4 is expressed on the surface of peripheral T-cells, thymocytes, on macrophages and granulocytes. It acts as a cellular adhesion molecule binding MHC class 2 molecules. Moreover, CD4 also acts as a receptor for HIV but requires cosignals. CD4 expression in brain suggests that it may play a more general role in mediating cell recognition events than merely those of cellular immune responses. CD4(+) cells are T-helper cells which, upon cell activation, produce a number of different cytokines and play a role in the activation and/or proliferation of B-cells, cytotoxic T-lymphocytes, and macrophages. Thymocytes which are CD4(+) and CD8(-) produce factors such as IL4, IL5, IL10 and IFN-gamma. CD4 is a 55 kDa transmembrane glycoprotein belonging to the immunoglobulin superfamily.
Research Area Immunology, Adaptive Immunity, Hematopoietic Progenitors, CD Antigens, Surface Receptors of Immune Cells
Pathways TCR Signaling

Application Details

Product Details anti-CD4 Antibody Target Details CD4 Handling Images back to top
Application Notes Blocking, staining and activating antibody. Blocks blinding of HIV to CD4. For staining, use 10 µl/10⁶ cells. Titer for blocking and activating T cells should be determined individually by the investigator. Antibody might also be suited for other applications not tested so far.
Restrictions For Research Use only

Handling

Product Details anti-CD4 Antibody Target Details CD4 Application Details Images back to top
Format Lyophilized
Buffer NA
Handling Advice Please Note: Always centrifuge product briefly before opening vial. Reconstitute with 0.5 ml sterile H20 or PBS to give a 1 mg/ml concentration. Mix gently, wash the sides of the vial and wait 30-60 seconds before use. Protein concentration: 1 mg/ml (after reconstitution).
Storage 4 °C/-20 °C