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anti-Human CD8 antibody for Enzyme Immunoassay

Recommended CD8 Antibody (supplied by: Log in to see )

Antigen
CD8a Molecule (CD8A) Antibodies
  • cd8
  • LOC100136450
  • BB154331
  • Ly-2
  • Ly-35
  • Ly-B
  • Lyt-2
  • zgc:136643
  • CD8
  • Leu2
  • MAL
  • p32
  • RHACD8-4
  • CD8 antigen, alpha chain
  • CD8 antigen, alpha polypeptide
  • CD8 alpha
  • T-cell surface glycoprotein CD8 alpha chain-like
  • CD8a molecule
  • Cd8a
  • cd8
  • LOC100136450
  • LOC100387674
  • cd8a
  • CD8A
Epitope
AA 66-96, N-Term
105
27
20
19
15
14
14
9
7
7
6
5
4
4
4
3
3
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
Reactivity
Human
1050
536
161
77
50
41
22
22
20
20
19
16
15
13
13
12
12
12
11
11
10
10
8
3
3
2
2
2
2
1
1
1
1
Host
Rabbit
1284
510
214
1
Clonality
Polyclonal
Conjugate
This CD8 antibody is un-conjugated
261
219
141
81
57
45
42
38
34
30
29
28
26
26
25
25
25
24
21
21
19
17
16
15
11
10
10
10
9
6
6
4
4
4
4
3
3
3
3
3
3
3
3
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
1627
452
449
316
271
266
260
246
234
39
33
25
24
23
18
14
11
10
7
7
6
6
6
5
4
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
Supplier
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Catalog No. ABIN4620512
$ 375.38
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN4620511 EIA IHC (p) WB Rabbit Ig C-Term Log in to see Polyclonal 2
1 ABIN1106567 EIA Mouse IgG1 Log in to see RAVB3 1
1 ABIN2718308 EIA IHC (p) WB Rabbit IgG Log in to see Polyclonal

Top referenced anti-CD8 antibody for Enzyme Immunoassay

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General

Antigen CD8a Molecule (CD8A) Antibodies
Epitope AA 66-96, N-Term
(105), (27), (20), (19), (15), (14), (14), (9), (7), (7), (6), (5), (4), (4), (4), (3), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(1050), (536), (161), (77), (50), (41), (22), (22), (20), (20), (19), (16), (15), (13), (13), (12), (12), (12), (11), (11), (10), (10), (8), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1)
Host Rabbit
(1284), (510), (214), (1)
Clonality
Polyclonal
Conjugate This CD8 antibody is un-conjugated
(261), (219), (141), (81), (57), (45), (42), (38), (34), (30), (29), (28), (26), (26), (25), (25), (25), (24), (21), (21), (19), (17), (16), (15), (11), (10), (10), (10), (9), (6), (6), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(1627), (452), (449), (316), (271), (266), (260), (246), (234), (39), (33), (25), (24), (23), (18), (14), (11), (10), (7), (7), (6), (6), (6), (5), (4), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Pubmed 2 references available
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Product Details anti-CD8 Antibody

Target Details CD8 Application Details Handling References for anti-CD8 Antibody (ABIN4620512) Images
Specificity This antibody detects Human CD8A at N-term.
Purification Protein A column, followed by peptide affinity purification
Immunogen KLH conjugated synthetic peptide between 66~96 amino acids from the N-terminal region of Human CD8A
Isotype Ig

Target Details CD8

Product Details anti-CD8 Antibody Application Details Handling References for anti-CD8 Antibody (ABIN4620512) Images back to top
Antigen
Alternative Name CD8 (CD8A Antibody Abstract)
Background The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains.Synonyms: CD8 alpha chain, CD8A, MAL, T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2
Molecular Weight 25729 Da
Gene ID 925, 9606
UniProt P01732
Research Area Immunology, Adaptive Immunity, Hematopoietic Progenitors, CD Antigens, Surface Receptors of Immune Cells
Pathways TCR Signaling

Application Details

Product Details anti-CD8 Antibody Target Details CD8 Handling References for anti-CD8 Antibody (ABIN4620512) Images back to top
Application Notes ELISA 1: 1,000. Western blot 1: 50 - 1: 100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-CD8 Antibody Target Details CD8 Application Details References for anti-CD8 Antibody (ABIN4620512) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

References for anti-CD8 Antibody (ABIN4620512)

Product Details anti-CD8 Antibody Target Details CD8 Application Details Handling Images back to top
Background publications

Mancebo, Moreno-Pelayo, Mencía, de la Calle-Martín, Allende, Sivadorai, Kalaydjieva, Bertranpetit, Coto, Calleja-Antolín, Ruiz-Contreras, Paz-Artal: "Gly111Ser mutation in CD8A gene causing CD8 immunodeficiency is found in Spanish Gypsies." in: Molecular immunology, Vol. 45, Issue 2, pp. 479-84, 2007

Zhou, Wang, Zhu, You, Zou: "CD8+FOXP3+T cells from renal transplant recipients in quiescence induce immunoglobulin-like transcripts-3 and -4 on dendritic cells from their respective donors." in: Transplantation proceedings, Vol. 39, Issue 10, pp. 3065-7, 2007

Images

Product Details anti-CD8 Antibody Target Details CD8 Application Details Handling References for anti-CD8 Antibody (ABIN4620512) back to top
Supplier Images
 image for anti-CD8 antibody (CD8a Molecule) (AA 66-96) (ABIN4620512) anti-CD8a Molecule (CD8A) (AA 66-96), (N-Term) antibody
 image for anti-CD8 antibody (CD8a Molecule) (AA 66-96) (ABIN4620512) anti-CD8a Molecule (CD8A) (AA 66-96), (N-Term) antibody (Image 2)
 image for anti-CD8 antibody (CD8a Molecule) (AA 66-96) (ABIN4620512) anti-CD8a Molecule (CD8A) (AA 66-96), (N-Term) antibody (Image 3)