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anti-Mouse (Murine) CD80 antibody for Immunocytochemistry

Recommended CD80 Antibody (supplied by: Log in to see )

Antigen
CD80 Antibodies
  • B7
  • B7-1
  • B7.1
  • B71
  • BB1
  • CD8
  • Cd28l
  • CD28LG
  • CD28LG1
  • LAB7
  • Leu2
  • Ly-53
  • Ly53
  • MAL
  • MIC17
  • p32
  • TSA1
Reactivity
Mouse (Murine)
411
275
50
17
10
9
8
3
2
2
2
Host
Hamster
383
113
99
72
50
17
Clonality
Monoclonal
Conjugate
This CD80 antibody is conjugated to PE-Cy5
79
78
52
26
17
15
14
12
11
11
7
7
6
6
6
6
6
6
5
5
5
4
4
3
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
Application
ELISA (Capture), ELISpot (Capture) (ELISPOT (Capture)), Immunocytochemistry (ICC), Mass Cytometry (CyTOF), Immunoprecipitation (IP), Neutralization (Neut), Immunohistochemistry (IHC)
496
207
116
114
101
66
46
44
33
22
16
15
14
7
7
7
6
5
5
4
3
2
2
1
1
1
1
1
Supplier
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Available images

Catalog No. ABIN2659009
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0009962841 ABIN2657475 ICC IF IP IHC ELISA WB Alexa Fluor 488 Hamster IgG Log in to see 16-10A1 11
0.0009962841 ABIN2659010 ELISA (Capture) ELISPOT (Capture) ICC CyTOF IP Neut IHC PE-Cy5 Hamster IgG Log in to see 16-10A1 12
0.0009962841 ABIN2657476 ICC IF IP IHC ELISA WB Alexa Fluor 488 Hamster IgG Log in to see 16-10A1 11
0.0009962841 ABIN217937 ICC Rat IgG2a Log in to see
0.0009962841 ABIN956674 ICC FACS ELISA WB Goat IgG Log in to see Polyclonal
0.0009962841 ABIN1854865 ICC IF IHC WB Mouse IgG2b Extracellular Log in to see
0.0009962841 ABIN645569 ICC Rat IgG2a Log in to see

Top referenced anti-CD80 antibody for Immunocytochemistry

Similar anti-CD80 Antibodies

Application / Reactivity Mouse (Murine)
Blocking Antibody (Inhibition) 2 Antibodies
Blocking Reagent (BR) 6 Antibodies
Depletion (Dep) 2 Antibodies
Dot Blot (DB) 1 Antibodies
ELISA 21 Antibodies
ELISA (Capture) 4 Antibodies
ELISpot (Capture) (ELISPOT (Capture)) 2 Antibodies
Enzyme Immunoassay (EIA) 5 Antibodies
Flow Cytometry (FACS) 220 Antibodies
Functional Studies (Func) 21 Antibodies
Immunochromatography (IC) 1 Antibodies
Immunocytochemistry (ICC) 8 Antibodies
Immunofluorescence (IF) 6 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies
Immunohistochemistry (IHC) 43 Antibodies
Immunohistochemistry (Acetone-fixed) (IHC (af)) 4 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 39 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 20 Antibodies
Immunoprecipitation (IP) 56 Antibodies

General

Antigen CD80 Antibodies
Reactivity Mouse (Murine)
(411), (275), (50), (17), (10), (9), (8), (3), (2), (2), (2)
Host Hamster
(383), (113), (99), (72), (50), (17)
Clonality (Clone)
Monoclonal   ( )
Conjugate This CD80 antibody is conjugated to PE-Cy5
(79), (78), (52), (26), (17), (15), (14), (12), (11), (11), (7), (7), (6), (6), (6), (6), (6), (6), (5), (5), (5), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Application ELISA (Capture), ELISpot (Capture) (ELISPOT (Capture)), Immunocytochemistry (ICC), Mass Cytometry (CyTOF), Immunoprecipitation (IP), Neutralization (Neut), Immunohistochemistry (IHC)
(496), (207), (116), (114), (101), (66), (46), (44), (33), (22), (16), (15), (14), (7), (7), (7), (6), (5), (5), (4), (3), (2), (2), (1), (1), (1), (1), (1)
Pubmed 11 references available
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Product Details anti-CD80 Antibody

Target Details CD80 Application Details Handling References for anti-CD80 Antibody (ABIN2659009) Images
Cross-Reactivity Dog (Canine)
Purification The antibody was purified by affinity chromatography, and conjugated with PE/Cy5 under optimal conditions. The solution is free of unconjugated PE/Cy5 and unconjugated antibody.
Clone 16-10A1
Isotype IgG

Target Details CD80

Product Details anti-CD80 Antibody Application Details Handling References for anti-CD80 Antibody (ABIN2659009) Images back to top
Antigen
Alternative Name CD80 (CD80 Antibody Abstract)
Background CD80 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD80 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD80 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD80 appears to be expressed later in the immune response than CD86. CD80 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.
Research Area Stem Cells, Hematopoietic Progenitors, Adaptive Immunity, CD Antigens, Surface Receptors of Immune Cells
Pathways TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway

Application Details

Product Details anti-CD80 Antibody Target Details CD80 Handling References for anti-CD80 Antibody (ABIN2659009) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-CD80 Antibody Target Details CD80 Application Details References for anti-CD80 Antibody (ABIN2659009) Images back to top
Concentration 0.2 mg/mL
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Protect from prolonged exposure to light. Do not freeze.
Storage 4 °C
Storage Comment The antibody solution should be stored undiluted between 2°C and 8°C.

References for anti-CD80 Antibody (ABIN2659009)

Product Details anti-CD80 Antibody Target Details CD80 Application Details Handling Images back to top
Background publications

Misra, Shi, Moreno-Garcia, Thankappan, Tighe, Mousseau, Kusser, Becker-Herman, Hudkins, Dunn, Kehry, Migone, Marshak-Rothstein, Simon, Randall, Alpers, Liggitt, Rawlings, Lund: "G alpha q-containing G proteins regulate B cell selection and survival and are required to prevent B cell-dependent autoimmunity." in: The Journal of experimental medicine, Vol. 207, Issue 8, pp. 1775-89, 2010

Lawson, Manenkova, Ahamed, Chen, Zou, Baccala, Theofilopoulos, Yuan: "Inhibition of transmethylation down-regulates CD4 T cell activation and curtails development of autoimmunity in a model system." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 178, Issue 8, pp. 5366-74, 2007

Turnquist, Raimondi, Zahorchak, Fischer, Wang, Thomson: "Rapamycin-conditioned dendritic cells are poor stimulators of allogeneic CD4+ T cells, but enrich for antigen-specific Foxp3+ T regulatory cells and promote organ transplant tolerance." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 178, Issue 11, pp. 7018-31, 2007

Ma, Xu, An, Dong, Lin, Shi, Wu: "Vaccine with beta-defensin 2-transduced leukemic cells activates innate and adaptive immunity to elicit potent antileukemia responses." in: Cancer research, Vol. 66, Issue 2, pp. 1169-76, 2006

Andoniou, van Dommelen, Voigt, Andrews, Brizard, Asselin-Paturel, Delale, Stacey, Trinchieri, Degli-Esposti: "Interaction between conventional dendritic cells and natural killer cells is integral to the activation of effective antiviral immunity." in: Nature immunology, Vol. 6, Issue 10, pp. 1011-9, 2005

Salomon, Bluestone: "Complexities of CD28/B7: CTLA-4 costimulatory pathways in autoimmunity and transplantation." in: Annual review of immunology, Vol. 19, pp. 225-52, 2001

Herold, Vezys, Koons, Lenschow, Thompson, Bluestone: "CD28/B7 costimulation regulates autoimmune diabetes induced with multiple low doses of streptozotocin." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 158, Issue 2, pp. 984-91, 1997

Harlan, Hengartner, Huang, Kang, Abe, Moreadith, Pircher, Gray, Ohashi, Freeman: "Mice expressing both B7-1 and viral glycoprotein on pancreatic beta cells along with glycoprotein-specific transgenic T cells develop diabetes due to a breakdown of T-lymphocyte unresponsiveness." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 91, Issue 8, pp. 3137-41, 1994

Hathcock, Laszlo, Pucillo, Linsley, Hodes: "Comparative analysis of B7-1 and B7-2 costimulatory ligands: expression and function." in: The Journal of experimental medicine, Vol. 180, Issue 2, pp. 631-40, 1994

Razi-Wolf, Freeman, Galvin, Benacerraf, Nadler, Reiser: "Expression and function of the murine B7 antigen, the major costimulatory molecule expressed by peritoneal exudate cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 89, Issue 9, pp. 4210-4, 1992

Linsley, Brady, Urnes, Grosmaire, Damle, Ledbetter: "CTLA-4 is a second receptor for the B cell activation antigen B7." in: The Journal of experimental medicine, Vol. 174, Issue 3, pp. 561-9, 1991

Images

Product Details anti-CD80 Antibody Target Details CD80 Application Details Handling References for anti-CD80 Antibody (ABIN2659009) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-CD80 antibody (CD80)  (PE-Cy5) (ABIN2659009) anti-CD80 (CD80) antibody (PE-Cy5)