anti-Human CD83 antibody for Biochemical Assay

Recommended CD83 Antibody (supplied by: Log in to see )

Antigen
CD83 Antibodies
  • BL11
  • HB15
  • CD83 molecule
  • CD83 antigen
  • Cd83
  • CD83
Reactivity
Human
240
99
41
20
15
7
5
5
5
2
1
1
Host
Mouse
164
73
56
13
Clonality
Monoclonal
Conjugate
This CD83 antibody is conjugated to APC
35
27
18
14
13
7
7
5
5
5
5
5
5
4
4
4
4
4
4
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
Application
Biochemical Assay (BCA)
207
63
61
32
29
26
21
20
11
9
9
4
2
2
2
1
1
1
1
1
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Catalog No. ABIN2658722
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN2658723 BCA APC Mouse IgG1 kappa Log in to see HB15e 7

General

Antigen CD83 Antibodies
Reactivity Human
(240), (99), (41), (20), (15), (7), (5), (5), (5), (2), (1), (1)
Host Mouse
(164), (73), (56), (13)
Clonality (Clone)
Monoclonal   ( )
Conjugate This CD83 antibody is conjugated to APC
(35), (27), (18), (14), (13), (7), (7), (5), (5), (5), (5), (5), (5), (4), (4), (4), (4), (4), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Application Biochemical Assay (BCA)
(207), (63), (61), (32), (29), (26), (21), (20), (11), (9), (9), (4), (2), (2), (2), (1), (1), (1), (1), (1)
Pubmed 7 references available
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Product Details anti-CD83 Antibody

Target Details CD83 Application Details Handling References for anti-CD83 antibody (ABIN2658722) Images
Cross-Reactivity Chimpanzee, Baboon, Cynomolgus, Rhesus Monkey, Pigtailed Macaque
Purification The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.
Clone HB15e
Isotype IgG1 kappa

Target Details CD83

Product Details anti-CD83 Antibody Application Details Handling References for anti-CD83 antibody (ABIN2658722) Images back to top
Antigen
Alternative Name CD83 (CD83 Antibody Abstract)
Background CD83 is a 43 kD single chain type I glycoprotein also known as HB15. A member of the immunoglobulin superfamily, CD83 is expressed on a subset of dendritic cells, Langerhans cells, and weakly on activated lymphocytes. Although CD83 is thought to play a role in antigen presentation and/or lymphocyte activation, the precise function of this protein is unknown. CD83 is considered to be a useful marker for mature dendritic cells.
Research Area Immunology, CD Antigens, Adaptive Immunity, Surface Receptors of Immune Cells

Application Details

Product Details anti-CD83 Antibody Target Details CD83 Handling References for anti-CD83 antibody (ABIN2658722) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-CD83 Antibody Target Details CD83 Application Details References for anti-CD83 antibody (ABIN2658722) Images back to top
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Protect from prolonged exposure to light. Do not freeze.
Storage 4 °C
Storage Comment The antibody solution should be stored undiluted between 2°C and 8°C.

References for anti-CD83 antibody (ABIN2658722)

Product Details anti-CD83 Antibody Target Details CD83 Application Details Handling Images back to top
Background publications

Shey, Nemes, Whatney, de Kock, Africa, Barnard, van Rooyen, Stone, Riou, Kollmann, Hawn, Scriba, Hanekom: "Maturation of innate responses to mycobacteria over the first nine months of life." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 192, Issue 10, pp. 4833-43, 2014

Huizinga, van Rijs, Bajramovic, Kuijf, Laman, Samsom, Jacobs: "Sialylation of Campylobacter jejuni endotoxin promotes dendritic cell-mediated B cell responses through CD14-dependent production of IFN-? and TNF-?." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 191, Issue 11, pp. 5636-45, 2013

Cao, Lee, Lu: "CD83 is preformed inside monocytes, macrophages and dendritic cells, but it is only stably expressed on activated dendritic cells." in: The Biochemical journal, Vol. 385, Issue Pt 1, pp. 85-93, 2004

Loré, Sönnerborg, Broström, Goh, Perrin, McDade, Stellbrink, Gazzard, Weber, Napolitano, van Kooyk, Andersson: "Accumulation of DC-SIGN+CD40+ dendritic cells with reduced CD80 and CD86 expression in lymphoid tissue during acute HIV-1 infection." in: AIDS, Vol. 16, Issue 5, pp. 683-92, 2002

Zhou, Tedder: "A distinct pattern of cytokine gene expression by human CD83+ blood dendritic cells." in: Blood, Vol. 86, Issue 9, pp. 3295-301, 1995

Kozlow, Wilson, Fox, Kehrl: "Subtractive cDNA cloning of a novel member of the Ig gene superfamily expressed at high levels in activated B lymphocytes." in: Blood, Vol. 81, Issue 2, pp. 454-61, 1993

Zhou, Schwarting, Smith, Tedder: "A novel cell-surface molecule expressed by human interdigitating reticulum cells, Langerhans cells, and activated lymphocytes is a new member of the Ig superfamily." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 149, Issue 2, pp. 735-42, 1992

Images

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Supplier Images
Flow Cytometry (FACS) image for anti-CD83 (CD83) antibody (APC) (ABIN2658722) anti-CD83 (CD83) antibody (APC)