anti-Human CD83 antibody for Enzyme Immunoassay

Recommended CD83 Antibody (supplied by: Log in to see )

Antigen
CD83 Antibodies
  • BL11
  • HB15
  • CD83 molecule
  • CD83 antigen
  • Cd83
  • CD83
Reactivity
Human
227
97
41
20
15
7
5
5
5
2
1
1
Host
Rabbit
154
72
56
9
Clonality
Polyclonal
Conjugate
This CD83 antibody is un-conjugated
33
27
17
13
12
6
6
5
5
5
4
4
4
4
4
4
4
4
4
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
192
63
57
31
29
26
21
20
11
7
6
4
2
2
2
1
1
1
1
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Catalog No. ABIN272283
$ 390.50
Plus shipping costs $45.00

General

Antigen CD83 Antibodies
Reactivity Human
(227), (97), (41), (20), (15), (7), (5), (5), (5), (2), (1), (1)
Host Rabbit
(154), (72), (56), (9)
Clonality
Polyclonal
Conjugate This CD83 antibody is un-conjugated
(33), (27), (17), (13), (12), (6), (6), (5), (5), (5), (4), (4), (4), (4), (4), (4), (4), (4), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(192), (63), (57), (31), (29), (26), (21), (20), (11), (7), (6), (4), (2), (2), (2), (1), (1), (1), (1)
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Product Details anti-CD83 Antibody

Target Details CD83 Application Details Handling Images
Specificity This antibody detects endogenous levels of CD83 protein. (region surrounding Pro130)
Cross-Reactivity (Details) Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.
Purification Affinity Chromatography using epitope-specific immunogen

Target Details CD83

Product Details anti-CD83 Antibody Application Details Handling Images back to top
Antigen
Alternative Name CD83 (CD83 Antibody Abstract)
Background CD83 is a heavily glycosylated membrane protein of the immunoglobulin (Ig) superfamily that is expressed in mature dendritic cells, Langerhans cells and interdigitating reticulum cells within lymphoid tissues. Structurally, CD83 resembles other Ig superfamily members, which have an extracellular V-type Ig-like domain, a single transmembrane domain and a 40 residue cytoplasmic tail. CD83 expression is used as a marker for mature, antigen presenting dendritic cells that are capable of generating tumor-specific T cell immunity, a phenotype with implications as an anticancer vaccine. CD83-IgG1(fc) chimera studies indicate that CD83 is a sialic acid-binding, Ig-like lectin (Siglec) adhesion molecule that is involved in cell adhesion/signaling by hosting dendritic cell interactions with monocytes and CD8+ T cells.Synonyms: B-cell activation protein, Cell surface protein HB15, HB15
Molecular Weight approx. 23, 45 kDa
Gene ID 9308
NCBI Accession NP_001035370
UniProt Q01151
Research Area Immunology, CD Antigens, Adaptive Immunity, Surface Receptors of Immune Cells

Application Details

Product Details anti-CD83 Antibody Target Details CD83 Handling Images back to top
Application Notes ELISA: 1/1000approx. 1/5000. Western Blot: 1/500approx. 1/1000. Immunohistochemistry: 1/50approx. 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-CD83 Antibody Target Details CD83 Application Details Images back to top
Concentration 1.0 mg/mL
Buffer Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C one month or (in aliquots) at -20 °C for longer.

Images

Product Details anti-CD83 Antibody Target Details CD83 Application Details Handling back to top
Supplier Images
 image for anti-CD83 (CD83) antibody (ABIN272283) anti-CD83 (CD83) antibody
 image for anti-CD83 (CD83) antibody (ABIN272283) anti-CD83 (CD83) antibody (Image 2)