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|Application / Reactivity||Human|
|Biochemical Assay (BCA)||2 Antibodies|
|Enzyme Immunoassay (EIA)||1 Antibodies|
|Flow Cytometry (FACS)||81 Antibodies|
|Immunocytochemistry (ICC)||4 Antibodies|
|Immunofluorescence (IF)||19 Antibodies|
|Immunofluorescence (Paraffin-embedded Sections) (IF (p))||11 Antibodies|
|Immunohistochemistry (IHC)||29 Antibodies|
|Immunohistochemistry (Frozen Sections) (IHC (fro))||6 Antibodies|
|Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))||8 Antibodies|
|Immunoprecipitation (IP)||7 Antibodies|
|Western Blotting (WB)||44 Antibodies|
|Conjugate||This CD83 antibody is conjugated to Biotin Alternatives|
Flow Cytometry (FACS)
|5 references available|
|Supplier||Log in to see|
Product Details anti-CD83 AntibodyTarget Details CD83 Application Details Handling References for anti-CD83 Antibody (ABIN2661136) Images
|Cross-Reactivity||Chimpanzee, Baboon, Cynomolgus, Rhesus Monkey, Pigtailed Macaque|
|Purification||The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.|
Target Details CD83Product Details anti-CD83 Antibody Application Details Handling References for anti-CD83 Antibody (ABIN2661136) Images back to top
|Alternative Name||CD83 (CD83 Antibody Abstract)|
|Background||CD83 is a 43 kD single chain type I glycoprotein also known as HB15. A member of the immunoglobulin superfamily, CD83 is expressed on a subset of dendritic cells, Langerhans cells, and weakly on activated lymphocytes. Although CD83 is thought to play a role in antigen presentation and/or lymphocyte activation, the precise function of this protein is unknown. CD83 is considered to be a useful marker for mature dendritic cells.|
|Research Area||Immunology, CD Antigens, Adaptive Immunity, Surface Receptors of Immune Cells|
Application DetailsProduct Details anti-CD83 Antibody Target Details CD83 Handling References for anti-CD83 Antibody (ABIN2661136) Images back to top
|Application Notes||Optimal working dilution should be determined by the investigator.|
|Restrictions||For Research Use only|
HandlingProduct Details anti-CD83 Antibody Target Details CD83 Application Details References for anti-CD83 Antibody (ABIN2661136) Images back to top
|Buffer||Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.|
|Precaution of Use||This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||Do not freeze.|
|Storage Comment||The antibody solution should be stored undiluted between 2°C and 8°C.|
References for anti-CD83 Antibody (ABIN2661136)Product Details anti-CD83 Antibody Target Details CD83 Application Details Handling Images back to top
Cao, Lee, Lu: "CD83 is preformed inside monocytes, macrophages and dendritic cells, but it is only stably expressed on activated dendritic cells." in: The Biochemical journal, Vol. 385, Issue Pt 1, pp. 85-93, 2004 (PubMed).
Loré, Sönnerborg, Broström et al.: "Accumulation of DC-SIGN+CD40+ dendritic cells with reduced CD80 and CD86 expression in lymphoid tissue during acute HIV-1 infection." in: AIDS (London, England), Vol. 16, Issue 5, pp. 683-92, 2002 (PubMed).
Kozlow, Wilson, Fox et al.: "Subtractive cDNA cloning of a novel member of the Ig gene superfamily expressed at high levels in activated B lymphocytes." in: Blood, Vol. 81, Issue 2, pp. 454-61, 1993 (PubMed).
Zhou, Tedder: "A distinct pattern of cytokine gene expression by human CD83+ blood dendritic cells." in: Blood, Vol. 86, Issue 9, pp. 3295-301, 1995 (PubMed).
Zhou, Schwarting, Smith et al.: "A novel cell-surface molecule expressed by human interdigitating reticulum cells, Langerhans cells, and activated lymphocytes is a new member of the Ig superfamily." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 149, Issue 2, pp. 735-42, 1992 (PubMed).
ImagesProduct Details anti-CD83 Antibody Target Details CD83 Application Details Handling References for anti-CD83 Antibody (ABIN2661136) back to top