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anti-Rat (Rattus) CD83 antibody for ELISA

Recommended CD83 Antibody (supplied by: Log in to see )

Antigen
CD83 Antibodies
  • BL11
  • HB15
Epitope
AA 1-134
13
13
8
5
5
5
2
2
2
2
1
1
1
1
1
Reactivity
Rat (Rattus)
140
80
33
7
5
5
5
5
Host
Rabbit
92
62
47
3
Clonality
Polyclonal
Conjugate
This CD83 antibody is un-conjugated
29
25
12
7
6
6
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
Minimum Detection Limit
≤ 0.039 ng/well
Application
ELISA
122
49
31
26
22
21
11
9
6
5
2
2
2
2
1
Supplier
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Catalog No. ABIN2001715
$ 163.90
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0012155735 ABIN2691719 ELISA WB Rabbit Log in to see Polyclonal

Similar anti-CD83 Antibodies

Application / Reactivity Rat (Rattus)
ELISA 2 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 22 Antibodies
Immunohistochemistry (IHC) 5 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 6 Antibodies
Western Blotting (WB) 13 Antibodies

General

Antigen CD83 Antibodies
Epitope AA 1-134
(13), (13), (8), (5), (5), (5), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Reactivity Rat (Rattus)
(140), (80), (33), (7), (5), (5), (5), (5)
Host Rabbit
(92), (62), (47), (3)
Clonality
Polyclonal
Conjugate This CD83 antibody is un-conjugated
(29), (25), (12), (7), (6), (6), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Minimum Detection Limit ≤ 0.039 ng/well
Application ELISA
(122), (49), (31), (26), (22), (21), (11), (9), (6), (5), (2), (2), (2), (2), (1)
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Product Details anti-CD83 Antibody

Target Details CD83 Application Details Handling Images
Specificity Rat CD83
Characteristics Produced in rabbits immunized with purified, recombinant Rat CD83 (rR CD83, B2GV95, Met1-Ala134). Total IgG was purified by Protein A affinity chromatography.
Purification Affinity Purified
Sterility 0.2 μm filtered
Immunogen Recombinant Rat CD83 protein
Isotype IgG

Target Details CD83

Product Details anti-CD83 Antibody Application Details Handling Images back to top
Antigen
Alternative Name CD83 (CD83 Antibody Abstract)
Background CD83 antigen, also known as B-cell activation protein, Cell surface protein HB15 and CD83, is a single-pass type I membrane protein which contains one Ig-like V-type (immunoglobulin- like) domain. CD83 is a a conserved member of the immunoglobulin superfamily. CD83 is expressed by activated lymphocytes, Langerhans cells and interdigitating reticulum cells. CD83 is a fascinating cell surface molecule with a unique pattern of expression that has multiple confirmed functions in regulating immune system development and function. CD83 represents an intriguing target for immunotherapy due to its preferential expression on mature dendritic cells (DCs), the most efficient of antigen presenting cells. On the protein level, two different isoforms of CD83 exist: a membrane-bound and a soluble form. The isoforms are generated by different subsets of cells, including DCs, T-cells and B-cells, and also differ in their biological function. While the membrane-bound CD83 is of immune stimulatory capacity, activates T-cells and is important for the generation of thymocytes, the soluble CD83 has the opposite effect and has an immune inhibitory capacity. Due to its immune inhibitory function. CD83 may play a significant role in antigen presentation or the cellular interactions that follow lymphocyte activation. CD83 has great potential for treatment of autoimmune diseases, for organ transplantations, and for immunotherapy, just to name a few examples. Moreover, some viruses prevent recognition by the host's immune system by specifically targeting CD83 surface expression.
UniProt B2GV95
Research Area Immunology, CD Antigens, Adaptive Immunity, Surface Receptors of Immune Cells
Pathways TCR Signaling

Application Details

Product Details anti-CD83 Antibody Target Details CD83 Handling Images back to top
Application Notes Direct ELISA - This antibody can be used at 0.5-1 μg/mL with the appropriate secondary reagents to detect Rat CD83. The detection limit for Rat CD83 is approximately ≤ 0.039 ng/well.
Restrictions For Research Use only

Handling

Product Details anti-CD83 Antibody Target Details CD83 Application Details Images back to top
Buffer PBS with 5% trehalose
Preservative Without preservative
Handling Advice Avoid repeated freeze-thaw cycles.
Storage 4 °C/-20 °C/-80 °C
Storage Comment This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -70°C. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly.
Expiry Date 12 months