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Browse our anti-CD8A (CD8A) Antibodies

Full name:
anti-CD8 Antigen, alpha Polypeptide Antibodies (CD8A)
On are 242 CD8 Antigen, alpha Polypeptide (CD8A) Antibodies from 1 different suppliers available. A total of 242 CD8A products are currently listed.
BB154331, CD8, Leu2, Ly-2, Ly-35, Ly-B, Lyt-2, MAL, p32, RHACD8-4

Most Popular Reactivities for anti-CD8A (CD8A) Antibodies

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anti-Mouse (Murine) CD8A Antibodies:

anti-Human CD8A Antibodies:

anti-Rat (Rattus) CD8A Antibodies:

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Top referenced anti-CD8A Antibodies

  1. Mouse (Murine) Monoclonal CD8A Primary Antibody for FACS, ELISA - ABIN610246 : Hayes, Chawla, Corvera: TGF beta receptor internalization into EEA1-enriched early endosomes: role in signaling to Smad2. in The Journal of cell biology 2002 (PubMed)
    Show all 2 references for ABIN610246

  2. Mouse (Murine) Monoclonal CD8A Primary Antibody for FACS, ELISA - ABIN610245 : Schmidlin, Dery, DeFea, Slice, Patierno, Sternini, Grady, Bunnett: Dynamin and Rab5a-dependent trafficking and signaling of the neurokinin 1 receptor. in The Journal of biological chemistry 2001 (PubMed)
    Show all 2 references for ABIN610245

More Antibodies against CD8A Interaction Partners

Mouse (Murine) CD8 Antigen, alpha Polypeptide (CD8A) interaction partners

  1. The generation of cancer-specific CD8(+) CD69 (show CD69 Antibodies)(+)-expressing lymphocytes that inhibit colon cancer growth has been described.

  2. TCF-1-deficient CD4+ CD8+ double positive thymocytes fail to undergo TCR alpha Valpha14-Jalpha18 rearrangement and produce significantly fewer Natural killer T cells.

  3. Batf3 (show BATF3 Antibodies) deficiency is not critical for the generation of CD8alpha dendritic cells

  4. Lck (show LCK Antibodies)-CD8 interaction is required for initial CD8 recruitment.

  5. Brd1 (show BRD1 Antibodies)-mediated Hbo1 (show MYST2 Antibodies) activity is crucial for efficient activation of CD8 expression via acetylation at H3K14, which serves as an epigenetic mark that promotes the recruitment of transcription machinery to the CD8 enhancers.

  6. Ly49E is expressed on a high proportion of CD8alphaalpha-positive intestinal intraepithelial lymphocytes.

  7. Comparing the sequences of mouse, human, rat and dog Cd8a and Cd8b1 gene loci identified 10 evolutionarily conserved regions (ECR). 6 ECRs overlapped with previously identified Cd8 enhancers. ECR-4 recruits transcription factors to the Cd8ab gene complex.

  8. Data indicate that orphan G-protein-coupled receptor (show GPRC5C Antibodies) GPR18 (show GPR18 Antibodies) is required for the normal homeostasis of CD8alphaalpha gammadeltaT and alphabetaT and CD8alphabeta intestinal intraepithelial lymphocyte compartment.

  9. CD8alpha DCs, rather than CD8 T cells, are responsible for enhanced viral latency and recurrences.

  10. Downregulation of CD8 during type 2 olarization of murine CD8(+) effector T cells is associated with CpG methylation of several regions of the Cd8a locus.

Pig (Porcine) CD8 Antigen, alpha Polypeptide (CD8A) interaction partners

  1. Findings indicate associations of differentiation 8 alpha (CD8A) variants with T lymphocyte subpopulations and suggest applications in porcine breeding programs.

Human CD8 Antigen, alpha Polypeptide (CD8A) interaction partners

  1. Human mesenchymal stromal cells enhance the immunomodulatory function of CD8(+)CD28 (show CD28 Antibodies)(-) regulatory T cells.

  2. In localized colorectal cancer carriers, mRNA-based CD3Z (show CD247 Antibodies)/CD8 profiling of tumor immune response may have stage, site and tissue-specific prognostic significance, along with ESR1 (show ESR1 Antibodies) expression.

  3. Dendritic cells accumulate in the bone marrow of multiple myeloma patients and protect tumor plasma cells from CD8+ T-cell killing.

  4. Patients with the presence of CD8- and CD45RO-positive T cells in bone marrow demonstrated better survival of gastric cancer patients than those with the absence of these cells in bone marrow.

  5. CD58 (show CD58 Antibodies)/CD2 (show CD2 Antibodies) is the primary costimulatory pathway in human CD28 (show CD28 Antibodies)-CD8+ T cells.

  6. We suggest that unique set of interactions between CEACAM5 (show CEACAM5 Antibodies), CD1d (show CD1D Antibodies), and CD8 render CD1d (show CD1D Antibodies) more class I-like molecule, facilitating antigen presentation and activation of CD8(+)-suppressor regulatory T cells.

  7. More sCD8 circulating molecules were found in patients transfused with post-storage leucodepleted RBCs whose supernatants had large amounts of sHLA-I. sCD8 is a possible modulator of sHLA-I-mediated transfusion-related immunomodulation.

  8. CD8-positivity proved to be an independent prognostic predictor of worse outcome in pediatric anaplastic lymphoma kinase (show ALK Antibodies)-positive anaplastic large cell lymphoma.

  9. CREMalpha orchestrates epigenetic remodeling of the CD8A,B through the recruitment of DNA methyltransferase (show DNMT1 Antibodies) (DNMT (show DNMT1 Antibodies)) 3a and histone methyltransferase G9a (show EHMT2 Antibodies).

  10. Modified CD8A gene function may contribute to the development of refractory chronic rhinosinusitis via reduction of circulating CD8 lymphocytes.

CD8A Antigen Profile

Antigen Summary

The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with CD8A

  • CD8 antigen, alpha chain (Cd8a) antibody
  • CD8a molecule (CD8A) antibody
  • CD8a molecule (Cd8a) antibody
  • BB154331 antibody
  • CD8 antibody
  • Leu2 antibody
  • Ly-2 antibody
  • Ly-35 antibody
  • Ly-B antibody
  • Lyt-2 antibody
  • MAL antibody
  • p32 antibody
  • RHACD8-4 antibody

Protein level used designations for CD8A

Lyt-2.1 lymphocyte differentiation antigen (AA at 100) , T-cell surface glycoprotein CD8 alpha chain , T-cell surface glycoprotein Lyt-2 , CD8 alpha , CD8a molecule , CD8 antigen alpha polypeptide , CD8 antigen, alpha polypeptide (p32) , Leu2 T-lymphocyte antigen , OKT8 T-cell antigen , T cell co-receptor , T-cell antigen Leu2 , T-lymphocyte differentiation antigen T8/Leu-2 , T8 T-cell antigen , CD8 antigen 32 kDa chain , CD8 antigen alpha-chain , CD8 antigen, alpha chain , CD8 antigen, alpha-chain , OX-8 membrane antigen , CD8 antigen, alpha polypeptide

12525 Mus musculus
100379570 Cavia porcellus
396627 Sus scrofa
925 Homo sapiens
428800 Gallus gallus
24930 Rattus norvegicus
493799 Felis catus
403157 Canis lupus familiaris
101103464 Ovis aries
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