Browse our anti-Filamin A (FLNA) Antibodies

Full name:
anti-Filamin A, alpha Antibodies (FLNA)
On www.antibodies-online.com are 154 Filamin A, alpha (FLNA) Antibodies from 19 different suppliers available. Additionally we are shipping Filamin A Kits (32) and Filamin A Proteins (3) and many more products for this protein. A total of 195 Filamin A products are currently listed.
Synonyms:
ABP-280, ABPX, cb967, CG3937, Cher, CSBS, CVD1, Dilp2, Dmel\\CG3937, F730004A14Rik, fb98b06, Fil, filamin-1, FLN, FLN-A, Fln1, flna, FMD, joy, MGC147094, MNS, NHBP, OPD, OPD1, OPD2, RGD1560614, sko, wu:fb98b06, wu:fd09g03, wu:fd18g06, wu:fd49a06, XLVD, XMVD
list all antibodies Gene Name GeneID UniProt
FLNA 2316 P21333
FLNA 293860  
FLNA 192176 Q8BTM8

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anti-Human Filamin A Antibodies:

anti-Rat (Rattus) Filamin A Antibodies:

anti-Mouse (Murine) Filamin A Antibodies:

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Top referenced anti-Filamin A Antibodies

  1. Human Monoclonal Filamin A Primary Antibody for IHC (p), PLA - ABIN560922 : Valente, Logan, Mougou-Zerelli, Lee, Silhavy, Brancati, Iannicelli, Travaglini, Romani, Illi, Adams, Szymanska, Mazzotta, Lee, Tolentino, Swistun, Salpietro, Fede, Gabriel, Russ, Cibulskis, Sougnez et al.: Mutations in TMEM216 perturb ciliogenesis and cause Joubert, Meckel and related syndromes. ... in Nature genetics 2010 (PubMed)
    Show all 7 references for 560922

  2. Human Monoclonal Filamin A Primary Antibody for WB - ABIN1882243 : Gorlin, Yamin, Egan, Stewart, Stossel, Kwiatkowski, Hartwig: Human endothelial actin-binding protein (ABP-280, nonmuscle filamin): a molecular leaf spring. in The Journal of cell biology 1990 (PubMed)
    Show all 6 references for 1882243

  3. Human Polyclonal Filamin A Primary Antibody for ICC, IF - ABIN188803 : Thoms, Loveridge, Simpson, Clipson, Reinhardt, Dunlop, Stark: Nucleolar targeting of RelA(p65) is regulated by COMMD1-dependent ubiquitination. in Cancer research 2010 (PubMed)
    Show all 2 references for 188803

  4. Human Polyclonal Filamin A Primary Antibody for FACS, IF - ABIN392193 : Maceyka, Alvarez, Milstien, Spiegel: Filamin A links sphingosine kinase 1 and sphingosine-1-phosphate receptor 1 at lamellipodia to orchestrate cell migration. in Molecular and cellular biology 2008 (PubMed)

More Antibodies against Filamin A Interaction Partners

Zebrafish Filamin A, alpha (FLNA) interaction partners

  1. Knockdown of filamin A or vimentin (show VIM Antibodies) in normal cells profoundly suppresses apical extrusion of the neighbouring transformed cells.

Fruit Fly (Drosophila melanogaster) Filamin A, alpha (FLNA) interaction partners

  1. Here we show using Drosophila indirect flight mus (show KPTN Antibodies)cle that t (show FLNC Antibodies)he filamin ortholog Cheerio in conjunction with the giant elastic protein titin plays a crucial role in keeping thin filaments stably anchored at the Z-disc. We identify the filamin domains required for interaction with the (show TTN Antibodies) titin ortholog Sallimus, and we demonstrate a genetic interaction of filamin with titin and actin.

  2. study identifies Cher as a new target of JNK (show MAPK8 Antibodies) signaling that links cytoskeleton dynamics to tumor progression.

  3. Data indicate that during embryonic development, the expression of Filamin and Ten-m partially overlap in ectodermal cells.

  4. Filamin is required for ovarian follicle cell motility during oogenesis.

Human Filamin A, alpha (FLNA) interaction partners

  1. These results provide new insights into the regulation of SK2 (show KCNN2 Antibodies) channel trafficking by the cytoskeletal proteins FLNA and alpha-actinin2, involving distinct recycling pathways

  2. Respiratory failure secondary to progressive obstructive lung disease during infancy may be the presenting phenotype of FLNA-associated periventricular nodular heterotopia.

  3. The actin regulator FLNA interacts with the endoplasmic reticulum stress kinase PERK and this interaction is required for the efficient formation of ER-plasma membrane contact sites.

  4. CCR2B (show CCR2 Antibodies) and beta2AR (show ADRB2 Antibodies) signals to FLNa to stimulate its endocytosis and recycling to the plasma membrane.

  5. In humans, mutations in the actin-binding protein (show KPTN Antibodies) Filamin-C (show FLNC Antibodies) result in myopathies, but the underlying molecular function is not well understood. Here we show using Drosophila indirect flight muscle that the filamin ortholog Cheerio in conjunction with the giant elastic protein titin (show TTN Antibodies) plays a crucial role in keeping thin filaments stably anchored at the Z-disc

  6. Case Report: Reduced binding of mutant FLNa to beta3 and the facilitated recruitment of talin by beta3 on platelet stimulation, explaining the increased alphaIIbbeta3 activation and the ensuing gain-of-platelet functions.

  7. results reveal an unusual structural and thermodynamic basis for the P2204L-induced dysfunction of filamin and frontometaphyseal dysplasia disease.

  8. Mechanistic analysis revealed that FLNA suppresses pol III gene transcription by confining the recruitment of the RNA pol III transcription machinery at the promoters of the genes that are sensitive to the alteration of FLNA expression.

  9. FlnA more strongly binds RhoA (show RHOA Antibodies), although both filamins overlap with RhoA (show RHOA Antibodies) expression in the cell cytoplasm. FlnA promotes RhoA (show RHOA Antibodies) activation whereas FlnB (show FLNB Antibodies) indirectly inhibits this pathway. Moreover, FlnA loss leads to diminished expression of b1-integrin, whereas FlnB (show FLNB Antibodies) loss promotes integrin expression

  10. FLNA can function as a modulator of chemosensitivity to docetaxel in triple-negative breast cancer (TNBC) cells through regulation of the MAPK/ERK (show MAPK1 Antibodies) pathway both in vitro and in vivo. FLNA may serve as a novel therapeutic target for improvement of chemotherapy efficacy in TNBC.

Pig (Porcine) Filamin A, alpha (FLNA) interaction partners

  1. filamin reduces ENaC (show SCNN1A Antibodies) channel function through direct interaction on the cell surface

Mouse (Murine) Filamin A, alpha (FLNA) interaction partners

  1. FlnA binding to PACSIN2 (show PACSIN2 Antibodies) F-BAR domain regulates membrane tubulation in megakaryocytes and platelets.

  2. FlnA is a critical upstream element of the signaling cascade underlying the myogenic tone.

  3. Bones lacking filamin A are protected from estrogen-mediated post-menopausal osteoporosis

  4. findings suggest a model in which filamin A local translation following axon injury controls localized HDAC5 (show HDAC5 Antibodies) activity to promote axon regeneration.

  5. Deletion of filamin A in endothelial cells aggravated myocardial infarction-induced left ventricle dysfunction and cardiac failure as a result of defective endothelial response

  6. A new signaling set, phosphatidic acid-S6K1-FLNA-actin, sheds light into the morphogenic pathway of cytoskeletal structures that are crucial for adhesion and cell locomotion during inflammation and metastasis.

  7. Filamin-A is associated with neutrophil uropod retraction.

  8. Analysis of editing in the filamin A encoding mRNA shows very high editing levels outside the nervous system; further shows FLNA editing is mainly achieved by ADAR2 (show ADARB1 Antibodies) but that in some cases ADAR1 (show ADAR Antibodies) can efficiently compensate for ADAR2 (show ADARB1 Antibodies).

  9. Filamin a, b-interacting proteins, Cfm1 and Cfm2, are essential for the formation of cartilaginous skeleton.

  10. a major function of FLNa in modulating ion channel abundance and membrane trafficking in neurons, thereby shaping their biophysical properties and function.

Filamin A (FLNA) Antigen Profile

Antigen Summary

The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with Filamin A (FLNA)

  • filamin A, alpha (actin binding protein 280) (flna) antibody
  • filamin A, alpha (FLNA) antibody
  • filamin B, like (flnbl) antibody
  • filamin A, alpha (flna) antibody
  • cheerio (cher) antibody
  • filamin A, alpha (Flna) antibody
  • filamin, alpha (Flna) antibody
  • ABP-280 antibody
  • ABPX antibody
  • cb967 antibody
  • CG3937 antibody
  • Cher antibody
  • CSBS antibody
  • CVD1 antibody
  • Dilp2 antibody
  • Dmel\\CG3937 antibody
  • F730004A14Rik antibody
  • fb98b06 antibody
  • Fil antibody
  • filamin-1 antibody
  • FLN antibody
  • FLN-A antibody
  • Fln1 antibody
  • flna antibody
  • FMD antibody
  • joy antibody
  • MGC147094 antibody
  • MNS antibody
  • NHBP antibody
  • OPD antibody
  • OPD1 antibody
  • OPD2 antibody
  • RGD1560614 antibody
  • sko antibody
  • wu:fb98b06 antibody
  • wu:fd09g03 antibody
  • wu:fd18g06 antibody
  • wu:fd49a06 antibody
  • XLVD antibody
  • XMVD antibody

Protein level used designations for anti-Filamin A, alpha (FLNA) Antibodies

fd09g03 , filamin A, alpha (actin binding protein 280) , filamin B, like , filamin A, alpha , filamin-A , CG3937-PA , CG3937-PB , CG3937-PF , CG3937-PG , CG3937-PH , CG3937-PI , CG3937-PK , CG3937-PL , CG3937-PM , CG3937-PN , Filamin-1 , Filamin-A , cher-PA , cher-PB , cher-PF , cher-PG , cher-PH , cher-PI , cher-PK , cher-PL , cher-PM , cher-PN , filamin , filamin B , filamin isoform B , filamin-240 , shi kong , actin binding protein 280 , alpha-filamin , endothelial actin-binding protein , filamin-1 , non-muscle filamin , Endothelial actin-binding protein 280) , filamin, alpha , 450 kDa protein , FLN-A , GENA 379 , actin-binding protein 280 , dilated pupils 2 , filamin A

GENE ID SPECIES
562529 Danio rerio
699524 Macaca mulatta
569979 Danio rerio
587317 Strongylocentrotus purpuratus
779840 Xenopus (Silurana) tropicalis
100137263 Papio anubis
42066 Drosophila melanogaster
100380643 Salmo salar
2316 Homo sapiens
293860 Rattus norvegicus
481084 Canis lupus familiaris
733585 Sus scrofa
281165 Bos taurus
100328754 Oryctolagus cuniculus
100725162 Cavia porcellus
395261 Gallus gallus
101120390 Ovis aries
192176 Mus musculus
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