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anti-Human FYB antibody for Enzyme Immunoassay

Recommended FYB Antibody (supplied by: Log in to see )

Antigen
FYN-Binding Protein (FYB) Antibodies
  • ADAP
  • B630013F22Rik
  • fyb
  • FYB-120/130
  • p120/130
  • p120/p130
  • PRO0823
  • RGD1563421
  • SLAP-130
  • Slap130
Epitope
C-Term, AA 645-675
29
15
9
3
2
2
2
2
Reactivity
Human
73
24
17
2
2
Host
Rabbit
58
11
7
Clonality
Polyclonal
Conjugate
This FYB antibody is un-conjugated
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
61
39
14
11
6
3
3
2
2
2
Supplier
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Catalog No. ABIN952408
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008854307 ABIN499215 EIA IF WB Rabbit IgG C-Term Log in to see Polyclonal 4
0.0008854307 ABIN499217 EIA IF WB Rabbit IgG N-Term Log in to see Polyclonal 4
0.0008854307 ABIN1449787 EIA WB Goat Internal Region Log in to see Polyclonal

Top referenced anti-FYB antibody for Enzyme Immunoassay

Similar anti-FYB Antibodies

Application / Reactivity Human
ELISA 39 Antibodies
Enzyme Immunoassay (EIA) 4 Antibodies
Flow Cytometry (FACS) 2 Antibodies
Immunochromatography (IC) 2 Antibodies
Immunocytochemistry (ICC) 14 Antibodies
Immunofluorescence (IF) 6 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 3 Antibodies
Western Blotting (WB) 59 Antibodies

General

Antigen FYN-Binding Protein (FYB) Antibodies
Epitope C-Term, AA 645-675
(29), (15), (9), (3), (2), (2), (2), (2)
Reactivity Human
(73), (24), (17), (2), (2)
Host Rabbit
(58), (11), (7)
Clonality
Polyclonal
Conjugate This FYB antibody is un-conjugated
(3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Western Blotting (WB)
(61), (39), (14), (11), (6), (3), (3), (2), (2), (2)
Pubmed 3 references available
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Product Details anti-FYB Antibody

Target Details FYB Application Details Handling References for anti-FYB Antibody (ABIN952408) Images
Specificity This antibody recognizes Human FYN-binding protein (C-term).
Purification Protein A column, followed by peptide affinity purification
Immunogen KLH conjugated synthetic peptide between 645-675 amino acids from the C-terminal region of Human FYN-binding protein Genename: FYB
Isotype Ig

Target Details FYB

Product Details anti-FYB Antibody Application Details Handling References for anti-FYB Antibody (ABIN952408) Images back to top
Antigen
Alternative Name FYN-Binding Protein (FYB Antibody Abstract)
Background FYB acts as an adapter protein of the FYN and LCP2 signaling cascades in T cells. Modulates the expression of interleukin-2 (IL-2). Involved in platelet activation. Prevents the degradation of SKAP1 and SKAP2.Synonyms: Adhesion and degranulation promoting adaptor protein, FYB-120/130, FYN-T-binding protein, SLAP-130, SLAP130, SLP-76-associated phosphoprotein, p120/p130
Molecular Weight 85387 Da
Gene ID 2533
NCBI Accession NP_955367
Pathways TCR Signaling

Application Details

Product Details anti-FYB Antibody Target Details FYB Handling References for anti-FYB Antibody (ABIN952408) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-FYB Antibody Target Details FYB Application Details References for anti-FYB Antibody (ABIN952408) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-FYB Antibody (ABIN952408)

Product Details anti-FYB Antibody Target Details FYB Application Details Handling Images back to top
Background publications

Srivastava, Burbach, Shimizu: "NF-kappaB activation in T cells requires discrete control of IkappaB kinase alpha/beta (IKKalpha/beta) phosphorylation and IKKgamma ubiquitination by the ADAP adapter protein." in: The Journal of biological chemistry, Vol. 285, Issue 15, pp. 11100-5, 2010

Lehmann, Meyer, Schuemann, Krause, Freund: "A novel S3S-TAP-tag for the isolation of T-cell interaction partners of adhesion and degranulation promoting adaptor protein." in: Proteomics, Vol. 9, Issue 23, pp. 5288-95, 2009

Hanna, Kruskal, Ezekowitz, Bloom, Collier: "Role of macrophage oxidative burst in the action of anthrax lethal toxin." in: Molecular medicine (Cambridge, Mass.), Vol. 1, Issue 1, pp. 7-18, 1996

Images

Product Details anti-FYB Antibody Target Details FYB Application Details Handling References for anti-FYB Antibody (ABIN952408) back to top
Supplier Images
Western Blotting (WB) image for anti-FYB antibody (FYN-Binding Protein) (C-Term) (ABIN952408) Western blot analysis of FYB Antibody (C-term) Cat.-No AP51746PU-N  in MDA-MB435 cell...