anti-Mouse (Murine) FYB antibody for Immunofluorescence

Recommended FYB Antibody (supplied by: Log in to see )

Antigen
FYN-Binding Protein (FYB) Antibodies
  • fyb
  • ADAP
  • PRO0823
  • SLAP-130
  • B630013F22Rik
  • FYB-120/130
  • Slap130
  • p120/130
  • p120/p130
  • RGD1563421
  • FYN-binding protein
  • FYN binding protein
  • fyb
  • FYB
  • Fyb
Epitope
C-Term
19
9
9
7
4
2
2
2
1
1
1
Reactivity
Human, Mouse (Murine)
89
26
21
6
5
4
3
3
2
2
Host
Rabbit
57
22
9
2
Clonality
Polyclonal
Conjugate
This FYB antibody is un-conjugated
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Western Blotting (WB)
62
39
13
12
10
5
4
4
3
2
Supplier
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Catalog No. ABIN5554508
$ 375.38
Plus shipping costs $45.00

Similar anti-FYB Antibodies

Application / Reactivity Mouse (Murine) Human
ELISA 5 Antibodies 39 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies 4 Antibodies
Immunocytochemistry (ICC) 4 Antibodies 12 Antibodies
Immunofluorescence (IF) 1 Antibodies 6 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 13 Antibodies 13 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 3 Antibodies 4 Antibodies
Immunoprecipitation (IP) 2 Antibodies 3 Antibodies
Western Blotting (WB) 15 Antibodies
Flow Cytometry (FACS) 10 Antibodies
Immunochromatography (IC) 2 Antibodies

General

Antigen FYN-Binding Protein (FYB) Antibodies
Epitope C-Term
(19), (9), (9), (7), (4), (2), (2), (2), (1), (1), (1)
Reactivity Human, Mouse (Murine)
(89), (26), (21), (6), (5), (4), (3), (3), (2), (2)
Host Rabbit
(57), (22), (9), (2)
Clonality
Polyclonal
Conjugate This FYB antibody is un-conjugated
(3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunofluorescence (IF), Western Blotting (WB)
(62), (39), (13), (12), (10), (5), (4), (4), (3), (2)
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Product Details anti-FYB Antibody

Target Details FYB Application Details Handling Images
Specificity This antibody recognizes ADAP (C-term).
Purification Affinity chromatography purified via peptide column
Immunogen A 20 amino acid peptide from near the carboxy terminus of Human ADAP
Isotype IgG

Target Details FYB

Product Details anti-FYB Antibody Application Details Handling Images back to top
Antigen
Alternative Name FYN-Binding Protein (FYB Antibody Abstract)
Background The adhesion and degranulation adaptor protein (ADAP) was initially identified as a molecular adapter that couples T cell receptor (TCR) stimulation to the avidity of integrins governing T cell adhesion. TCR stimulation promotes the formation of a multi-protein complex containing CARMA1, MALT1, and BCL-10, which through the association of ADAP, ultimately activates the NF-kappaB family of transcription factors. More recent experiments have shown that ADAP controls optimal T cell proliferation, cytokine production, and expression of the Bcl-2 family member Bcl-x(L), suggesting that ADAP regulates T cell activation by promoting antigen-dependent T cell-antigen presenting cell (APC) activation. At least three isoforms of ADAP are known to exist.Synonyms: Adhesion and degranulation promoting adaptor protein, FYB-120/130, FYN-T-binding protein, SLAP-130, SLAP130, SLP-76-associated phosphoprotein, p120/p130
Gene ID 2533
NCBI Accession NP_955367
UniProt O15117
Pathways TCR Signaling, Protein targeting to Nucleus

Application Details

Product Details anti-FYB Antibody Target Details FYB Handling Images back to top
Application Notes ELISA. Western Blot: ADAP antibody can be used for detection of ADAP at 0.5 - 1 μg/mL. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-FYB Antibody Target Details FYB Application Details Images back to top
Buffer PBS containing 0.02 % Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.