anti-Human GATA3 antibody for Flow Cytometry

Recommended GATA3 Antibody (supplied by: Log in to see )

Antigen
GATA Binding Protein 3 (GATA3) Antibodies
  • HDR
  • HDRS
  • Gata-3
  • jal
  • cb550
  • gta3
  • GATA-3
  • XGATA3
  • xgata-3
  • hdr
  • xGATA-3
  • GATA3
  • GATA transcription factor 3
  • T4L20.260
  • T4L20_260
  • gata3
  • GATA binding protein 3
  • GATA-binding protein 3
  • GATA transcription factor 3
  • amidase
  • putative amidase
  • transcription factor GATA-3
  • GATA3
  • Gata3
  • gata3
  • gatA3
Reactivity
Human, Mouse (Murine)
221
123
53
15
13
10
7
7
6
5
5
4
4
2
2
1
Host
Mouse
122
77
21
9
Clonality
Monoclonal
Conjugate
This GATA3 antibody is conjugated to PerCP-Cy5.5
8
6
6
5
5
4
4
4
3
2
2
2
2
2
2
2
2
1
1
1
Application
Flow Cytometry (FACS)
167
90
65
37
35
27
25
13
6
6
2
1
1
1
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

Submit your validation data for this product and get a full refund. I want to validate this product

Learn more

Available images

Catalog No. ABIN2660186
Contact our Customer Service for availability and price in your country.
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
14.326361 ABIN2657201 FACS Alexa Fluor 647 Mouse IgG2b kappa Log in to see 16E10A23 6
14.326361 ABIN2658319 FACS APC Mouse IgG2b kappa Log in to see 16E10A23 5
14.326361 ABIN2662731 FACS PE Mouse IgG2b kappa Log in to see 16E10A23 4
14.326361 ABIN2657080 FACS Alexa Fluor 488 Mouse IgG2b kappa Log in to see 16E10A23 6
14.326361 ABIN4895787 FACS Fluorescein Mouse IgG1 AA 135-258 Log in to see 291106
14.326361 ABIN4895789 FACS Allophycocyanin Mouse IgG2b AA 135-258 Log in to see 634919
14.326361 ABIN4895788 FACS PE Mouse IgG1 AA 135-258 Log in to see 291106
14.326361 ABIN4895790 FACS Alexa Fluor 594 Mouse IgG2b AA 135-258 Log in to see 634919
14.326361 ABIN4313653 FACS IHC WB Mouse IgG1 Log in to see 8H4
14.326361 ABIN5012896 FACS WB Mouse IgG2b AA 135-258 Log in to see 634919
14.326361 ABIN3028672 FACS IF ELISA WB Mouse IgG2b, kappa Log in to see 1259CT707-136-102
1 ABIN2656844 FACS IHC ELISA Alexa Fluor 594 Mouse IgG2b kappa Log in to see 16E10A23 6
1 ABIN2666388 FACS Mouse IgG2b kappa Log in to see 16E10A23 6
1 ABIN2658320 FACS APC Mouse IgG2b kappa Log in to see 16E10A23 5
1 ABIN2662732 FACS PE Mouse IgG2b kappa Log in to see 16E10A23 4
1 ABIN2657202 FACS Alexa Fluor 647 Mouse IgG2b kappa Log in to see 16E10A23 6
1 ABIN2657081 FACS Alexa Fluor 488 Mouse IgG2b kappa Log in to see 16E10A23 6
1 ABIN2660187 FACS PerCP-Cy5.5 Mouse IgG2b kappa Log in to see 16E10A23 6
1 ABIN2881239 FACS IF WB Mouse IgG Log in to see Polyclonal
1 ABIN2666389 FACS Mouse IgG2b kappa Log in to see 16E10A23 6

General

Antigen GATA Binding Protein 3 (GATA3) Antibodies
Reactivity Human, Mouse (Murine)
(221), (123), (53), (15), (13), (10), (7), (7), (6), (5), (5), (4), (4), (2), (2), (1)
Host Mouse
(122), (77), (21), (9)
Clonality (Clone)
Monoclonal   ( )
Conjugate This GATA3 antibody is conjugated to PerCP-Cy5.5
(8), (6), (6), (5), (5), (4), (4), (4), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Application Flow Cytometry (FACS)
(167), (90), (65), (37), (35), (27), (25), (13), (6), (6), (2), (1), (1), (1), (1)
Pubmed 6 references available
Supplier Log in to see

Product Details anti-GATA3 Antibody

Target Details GATA3 Application Details Handling References for anti-GATA3 antibody (ABIN2660186) Images
Purification The antibody was purified by affinity chromatography and conjugated with PerCP/Cy5.5 under optimal conditions. The solution is free of unconjugated PerCP/Cy5.5 and unconjugated antibody.
Clone 16E10A23
Isotype IgG2b kappa

Target Details GATA3

Product Details anti-GATA3 Antibody Application Details Handling References for anti-GATA3 antibody (ABIN2660186) Images back to top
Antigen
Alternative Name GATA3 (GATA3 Antibody Abstract)
Background GATA3 functions as a major regulator of T helper 2 (Th2) cell differentiation in immune cells. GATA3 expression is upregulated through IL-4 receptor signaling or the Notch-mediated pathway, which results in production of IL-4, IL-5, and IL-13 cytokines, responsible for preferential differentiation of Th2-cells. GATA3 has been shown to regulate early developmental processes of T cells, such as T cell commitment, positive selection, and post-commitment CD4+ T cell survival. In the mammary gland, GATA3 plays an important role in differentiation and commitment of luminal epithelial cells. In a mouse model, exogenous expression of GATA3 in undifferentiated breast carcinoma cells induces differentiation and suppresses spreading of the tumor cells, suggesting that GATA3 is involved in preventing malignancy of breast cancer. GATA3 has been reported to be essential in the development of a variety of normal tissues. Defect in GATA3 results in hypoparathyroidism, sensorineural deafness, and renal dysplasia (HDR syndrome).
Research Area Lineage Markers, Transcription Factors, Adaptive Immunity
Pathways Hormone Transport, Regulation of Hormone Metabolic Process, Tube Formation

Application Details

Product Details anti-GATA3 Antibody Target Details GATA3 Handling References for anti-GATA3 antibody (ABIN2660186) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-GATA3 Antibody Target Details GATA3 Application Details References for anti-GATA3 antibody (ABIN2660186) Images back to top
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Protect from prolonged exposure to light. Do not freeze.
Storage 4 °C
Storage Comment The antibody solution should be stored undiluted between 2°C and 8°C.

References for anti-GATA3 antibody (ABIN2660186)

Product Details anti-GATA3 Antibody Target Details GATA3 Application Details Handling Images back to top
Background publications

Yagi, Zhu, Paul: "An updated view on transcription factor GATA3-mediated regulation of Th1 and Th2 cell differentiation." in: International immunology, Vol. 23, Issue 7, pp. 415-20, 2011

Ho, Tai, Pai: "GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation." in: Nature reviews. Immunology, Vol. 9, Issue 2, pp. 125-35, 2009

Chou, Provot, Werb: "GATA3 in development and cancer differentiation: cells GATA have it!" in: Journal of cellular physiology, Vol. 222, Issue 1, pp. 42-9, 2009

Kouros-Mehr, Kim, Bechis, Werb: "GATA-3 and the regulation of the mammary luminal cell fate." in: Current opinion in cell biology, Vol. 20, Issue 2, pp. 164-70, 2008

Rothenberg, Scripture-Adams: "Competition and collaboration: GATA-3, PU.1, and Notch signaling in early T-cell fate determination." in: Seminars in immunology, Vol. 20, Issue 4, pp. 236-46, 2008

Van Esch, Groenen, Nesbit, Schuffenhauer, Lichtner, Vanderlinden, Harding, Beetz, Bilous, Holdaway, Shaw, Fryns, Van de Ven, Thakker, Devriendt: "GATA3 haplo-insufficiency causes human HDR syndrome." in: Nature, Vol. 406, Issue 6794, pp. 419-22, 2000

Images

Product Details anti-GATA3 Antibody Target Details GATA3 Application Details Handling References for anti-GATA3 antibody (ABIN2660186) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-GATA Binding Protein 3 (GATA3) antibody (PerCP-Cy5.5) (ABIN2660186) anti-GATA Binding Protein 3 (GATA3) antibody (PerCP-Cy5.5)