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anti-Mouse (Murine) GATA3 antibody for Flow Cytometry

Recommended GATA3 Antibody (supplied by: Log in to see )

Antigen
GATA Binding Protein 3 (GATA3) Antibodies
  • cb550
  • GATA-3
  • Gata-3
  • gata3
  • GATA3
  • gta3
  • HDR
  • hdr
  • HDRS
  • jal
  • xGATA-3
  • xgata-3
  • XGATA3
Reactivity
Human, Mouse (Murine)
193
97
40
11
11
8
7
6
5
2
1
1
1
Host
Mouse
115
60
19
13
Clonality
Monoclonal
Conjugate
This GATA3 antibody is conjugated to Alexa Fluor 488
7
5
5
5
5
4
4
3
3
2
2
2
2
2
2
2
1
1
1
1
Application
Flow Cytometry (FACS)
146
82
56
27
23
21
20
16
6
6
2
1
1
1
Supplier
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Catalog No. ABIN2657080
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.30886927 ABIN2658319 FACS APC Mouse IgG2b kappa Log in to see 16E10A23 5
0.30886927 ABIN2657201 FACS Alexa Fluor 647 Mouse IgG2b kappa Log in to see 16E10A23 6
0.30886927 ABIN2660186 FACS PerCP-Cy5.5 Mouse IgG2b kappa Log in to see 16E10A23 6
0.30886927 ABIN2662731 FACS PE Mouse IgG2b kappa Log in to see 16E10A23 4
0.30886927 ABIN2679951 FACS ICS Alexa Fluor 488 Rat IgG2b kappa Log in to see TWAJ 1
0.30886927 ABIN1032106 FACS ICS PerCP-eFluor® 710 Rat IgG2b kappa Log in to see TWAJ
0.30886927 ABIN1032105 FACS ICS PE Rat IgG2b kappa Log in to see TWAJ
0.30886927 ABIN1032107 FACS ICS EFluor 660 Rat IgG2b kappa Log in to see TWAJ
0.30886927 ABIN2679949 FACS ICS PE-Cy7 Rat IgG2b kappa Log in to see TWAJ
0.30886927 ABIN2679953 FACS ICS PE-eFluor® 610 Rat IgG2b kappa Log in to see TWAJ
0.0010647682 ABIN2656844 FACS IHC ELISA Alexa Fluor 594 Mouse IgG2b kappa Log in to see 16E10A23 6
0.0010647682 ABIN475720 FACS PE Rat IgG2b, kappa Log in to see TWAJ
0.0010647682 ABIN2666388 FACS Mouse IgG2b kappa Log in to see 16E10A23 6
0.0010647682 ABIN2658320 FACS APC Mouse IgG2b kappa Log in to see 16E10A23 5
0.0010647682 ABIN2657202 FACS Alexa Fluor 647 Mouse IgG2b kappa Log in to see 16E10A23 6
0.0010647682 ABIN2657081 FACS Alexa Fluor 488 Mouse IgG2b kappa Log in to see 16E10A23 6
0.0010647682 ABIN2660187 FACS PerCP-Cy5.5 Mouse IgG2b kappa Log in to see 16E10A23 6
0.0010647682 ABIN2662732 FACS PE Mouse IgG2b kappa Log in to see 16E10A23 4
0.0010647682 ABIN2666389 FACS Mouse IgG2b kappa Log in to see 16E10A23 6

Top referenced anti-GATA3 antibody for Flow Cytometry

Similar anti-GATA3 Antibodies

Application / Reactivity Human Mouse (Murine)
Western Blotting (WB) 134 Antibodies 50 Antibodies
Intracellular Staining (ICS) 6 Antibodies 6 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 21 Antibodies 11 Antibodies
Immunohistochemistry (IHC) 57 Antibodies 25 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies
Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) 1 Antibodies 1 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 23 Antibodies 23 Antibodies
Immunofluorescence (IF) 25 Antibodies 20 Antibodies
Immunocytochemistry (ICC) 14 Antibodies 10 Antibodies
Immunochromatography (IC) 2 Antibodies 2 Antibodies

General

Antigen GATA Binding Protein 3 (GATA3) Antibodies
Reactivity Human, Mouse (Murine)
(193), (97), (40), (11), (11), (8), (7), (6), (5), (2), (1), (1), (1)
Host Mouse
(115), (60), (19), (13)
Clonality (Clone)
Monoclonal   ( )
Conjugate This GATA3 antibody is conjugated to Alexa Fluor 488
(7), (5), (5), (5), (5), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Application Flow Cytometry (FACS)
(146), (82), (56), (27), (23), (21), (20), (16), (6), (6), (2), (1), (1), (1)
Pubmed 6 references available
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Product Details anti-GATA3 Antibody

Target Details GATA3 Application Details Handling References for anti-GATA3 Antibody (ABIN2657080) Images
Purification The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 488 under optimal conditions.
Clone 16E10A23
Isotype IgG2b kappa

Target Details GATA3

Product Details anti-GATA3 Antibody Application Details Handling References for anti-GATA3 Antibody (ABIN2657080) Images back to top
Antigen
Alternative Name GATA3 (GATA3 Antibody Abstract)
Background GATA3 functions as a major regulator of T helper 2 (Th2) cell differentiation in immune cells. GATA3 expression is upregulated through IL-4 receptor signaling or the Notch-mediated pathway, which results in production of IL-4, IL-5, and IL-13 cytokines, responsible for preferential differentiation of Th2-cells. GATA3 has been shown to regulate early developmental processes of T cells, such as T cell commitment, positive selection, and post-commitment CD4+ T cell survival. In the mammary gland, GATA3 plays an important role in differentiation and commitment of luminal epithelial cells. In a mouse model, exogenous expression of GATA3 in undifferentiated breast carcinoma cells induces differentiation and suppresses spreading of the tumor cells, suggesting that GATA3 is involved in preventing malignancy of breast cancer. GATA3 has been reported to be essential in the development of a variety of normal tissues. Defect in GATA3 results in hypoparathyroidism, sensorineural deafness, and renal dysplasia (HDR syndrome).
Research Area Lineage Markers, Transcription Factors, Adaptive Immunity
Pathways TCR Signaling

Application Details

Product Details anti-GATA3 Antibody Target Details GATA3 Handling References for anti-GATA3 Antibody (ABIN2657080) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-GATA3 Antibody Target Details GATA3 Application Details References for anti-GATA3 Antibody (ABIN2657080) Images back to top
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Protect from prolonged exposure to light. Do not freeze.
Storage 4 °C
Storage Comment The antibody solution should be stored undiluted between 2°C and 8°C

References for anti-GATA3 Antibody (ABIN2657080)

Product Details anti-GATA3 Antibody Target Details GATA3 Application Details Handling Images back to top
Background publications

Yagi, Zhu, Paul: "An updated view on transcription factor GATA3-mediated regulation of Th1 and Th2 cell differentiation." in: International immunology, Vol. 23, Issue 7, pp. 415-20, 2011

Ho, Tai, Pai: "GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation." in: Nature reviews. Immunology, Vol. 9, Issue 2, pp. 125-35, 2009

Chou, Provot, Werb: "GATA3 in development and cancer differentiation: cells GATA have it!" in: Journal of cellular physiology, Vol. 222, Issue 1, pp. 42-9, 2009

Kouros-Mehr, Kim, Bechis, Werb: "GATA-3 and the regulation of the mammary luminal cell fate." in: Current opinion in cell biology, Vol. 20, Issue 2, pp. 164-70, 2008

Rothenberg, Scripture-Adams: "Competition and collaboration: GATA-3, PU.1, and Notch signaling in early T-cell fate determination." in: Seminars in immunology, Vol. 20, Issue 4, pp. 236-46, 2008

Van Esch, Groenen, Nesbit, Schuffenhauer, Lichtner, Vanderlinden, Harding, Beetz, Bilous, Holdaway, Shaw, Fryns, Van de Ven, Thakker, Devriendt: "GATA3 haplo-insufficiency causes human HDR syndrome." in: Nature, Vol. 406, Issue 6794, pp. 419-22, 2000

Images

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Supplier Images
Flow Cytometry (FACS) image for anti-GATA3 antibody (GATA Binding Protein 3)  (Alexa Fluor 488) (ABIN2657080) anti-GATA Binding Protein 3 (GATA3) antibody (Alexa Fluor 488)