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|Application / Reactivity||Human||Mouse (Murine)||Pig (Porcine)|
|Western Blotting (WB)||91 Antibodies||11 Antibodies||2 Antibodies|
|Proximity Ligation Assay (PLA)||1 Antibodies|
|Immunoprecipitation (IP)||11 Antibodies|
|Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))||14 Antibodies||4 Antibodies|
|Immunohistochemistry (IHC)||18 Antibodies||4 Antibodies|
|Immunohistochemistry (Frozen Sections) (IHC (fro))||1 Antibodies||1 Antibodies|
|Immunohistochemistry (Formalin-fixed Sections) (IHC (f))||1 Antibodies|
|Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))||1 Antibodies|
|Immunofluorescence (Paraffin-embedded Sections) (IF (p))||11 Antibodies||11 Antibodies|
|Immunofluorescence (IF)||1 Antibodies|
|Immunocytochemistry (ICC)||1 Antibodies||2 Antibodies|
|Antigen||GRB2-Related Adaptor Protein 2 (GRAP2) Antibodies|
|Reactivity||Human, Mouse (Murine), Pig (Porcine) Alternatives|
|Conjugate||This GRAP2 antibody is un-conjugated Alternatives|
Western Blotting (WB)
|1 reference available|
|Supplier||Log in to see|
Product Details anti-GRAP2 AntibodyTarget Details GRAP2 Application Details Handling References for anti-GRAP2 Antibody (ABIN374093) Images
|Specificity||This antibody detects GRAP2 at C-term.|
Species reactivity (expected):Mouse, Porcine.
Species reactivity (tested):Human.
|Immunogen||Peptide with sequence C-GLFPANYVAPMTR, from the C Terminus of the protein sequence Genename: GRAP2|
Target Details GRAP2Product Details anti-GRAP2 Antibody Application Details Handling References for anti-GRAP2 Antibody (ABIN374093) Images back to top
|Alternative Name||GRAP2 (GRAP2 Antibody Abstract)|
|Background||GRAP2 is a member of the GRB2/Sem5/Drk family. This member is an adaptor-like protein involved in leukocyte-specific protein-tyrosine kinase signaling. Like its related family member, GRB2-related adaptor protein (GRAP), this protein contains an SH2 domain flanked by two SH3 domains. This protein interacts with other proteins, such as GRB2-associated binding protein 1 (GAB1) and the SLP-76 leukocyte protein (LCP2), through its SH3 domains. Transcript variants utilizing alternative polyA sites exist.Synonyms: Adapter protein GRID, GADS, GRB-2-like protein, GRB2-related adapter protein 2, GRB2L, GRBLG, GRBX, GRID, Grf-40, Grf40 adapter protein, Growth factor receptor-binding protein, Hematopoietic cell-associated adapter protein GrpL, SH3-SH2-SH3 adapter Mona|
|Pathways||TCR Signaling, Fc-epsilon Receptor Signaling Pathway|
Application DetailsProduct Details anti-GRAP2 Antibody Target Details GRAP2 Handling References for anti-GRAP2 Antibody (ABIN374093) Images back to top
Peptide ELISA: 1/32000. Western blot: 1 - 3 μg/mL. Approx 38 kDa band seen in Jurkat lysate.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-GRAP2 Antibody Target Details GRAP2 Application Details References for anti-GRAP2 Antibody (ABIN374093) Images back to top
|Buffer||Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||Avoid repeated freezing and thawing.|
|Storage||4 °C/-20 °C|
|Storage Comment||Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.|
References for anti-GRAP2 Antibody (ABIN374093)Product Details anti-GRAP2 Antibody Target Details GRAP2 Application Details Handling Images back to top
Qiu, Hua, Agrawal, Li, Cai, Chan, Zhou, Luo, Liu: "Molecular cloning and expression of human grap-2, a novel leukocyte-specific SH2- and SH3-containing adaptor-like protein that binds to gab-1." in: Biochemical and biophysical research communications, Vol. 253, Issue 2, pp. 443-7, 1999
ImagesProduct Details anti-GRAP2 Antibody Target Details GRAP2 Application Details Handling References for anti-GRAP2 Antibody (ABIN374093) back to top