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anti-Mouse (Murine) ICOS antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended ICOS Antibody (supplied by: Log in to see )

Antigen
Inducible T-Cell Co-Stimulator (ICOS) Antibodies
  • AILIM
  • Ailim
  • CCLP
  • CD278
  • CRP-1
  • CVID1
  • H4
  • ICOS
  • Ly115
Epitope
C-Term
6
3
2
2
2
1
1
Reactivity
Human, Mouse (Murine)
60
56
42
1
Host
Rabbit
33
25
13
10
2
1
Clonality
Monoclonal
Conjugate
This ICOS antibody is un-conjugated
10
8
7
5
4
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
44
15
13
11
10
7
5
4
4
4
3
3
2
2
2
1
1
1
Supplier
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Catalog No. ABIN492678
$ 797.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008982679 ABIN742380 IF (p) IHC (p) WB Rabbit IgG Log in to see Polyclonal
0.0008982679 ABIN1173556 ICC IHC (fro) IHC (p) ELISA WB Rabbit IgG AA 35-131 Log in to see Polyclonal
0.0008982679 ABIN742382 IHC (p) WB Biotin Rabbit IgG Log in to see Polyclonal
0.0008982679 ABIN742389 IHC (p) WB HRP Rabbit IgG Log in to see Polyclonal

Similar anti-ICOS Antibodies

Application / Reactivity Human Mouse (Murine)
Western Blotting (WB) 10 Antibodies 9 Antibodies
Mass Cytometry (CyTOF) 1 Antibodies
Intracellular Flow Cytometry (ICFC) 4 Antibodies 4 Antibodies
Immunoprecipitation (IP) 3 Antibodies 4 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 12 Antibodies 5 Antibodies
Immunohistochemistry (IHC) 7 Antibodies 5 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 3 Antibodies 2 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies 11 Antibodies
Immunofluorescence (IF) 2 Antibodies 2 Antibodies
Immunocytochemistry (ICC) 1 Antibodies 1 Antibodies

General

Antigen Inducible T-Cell Co-Stimulator (ICOS) Antibodies
Epitope C-Term
(6), (3), (2), (2), (2), (1), (1)
Reactivity Human, Mouse (Murine)
(60), (56), (42), (1)
Host Rabbit
(33), (25), (13), (10), (2), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This ICOS antibody is un-conjugated
(10), (8), (7), (5), (4), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(44), (15), (13), (11), (10), (7), (5), (4), (4), (4), (3), (3), (2), (2), (2), (1), (1), (1)
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Product Details anti-ICOS Antibody

Target Details ICOS Application Details Handling Images
Specificity Recognizes CD278. Cellular localisation: Membrane
Cross-Reactivity (Details) Species reactivity (expected):Mouse, RatSpecies reactivity (tested):Human.
Purification Protein A/G Chromatography
Immunogen Synthetic peptide corresponding to the C-terminus of Human CD278.
Clone SP98
Isotype IgG

Target Details ICOS

Product Details anti-ICOS Antibody Application Details Handling Images back to top
Antigen
Alternative Name CD278 / ICOS (ICOS Antibody Abstract)
Background CD278 belongs to the CD28 and CTLA-4 cell-surface receptor family and is highly expressed in activated T-cells. It is essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. It enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells.Synonyms: AILIM, Activation-inducible lymphocyte immunomediatory molecule, Inducible T-cell costimulator
Molecular Weight 23 kDa
Gene ID 29851
NCBI Accession NP_036224
UniProt Q9Y6W8
Research Area Immunology, Inflammation
Pathways TCR Signaling

Application Details

Product Details anti-ICOS Antibody Target Details ICOS Handling Images back to top
Application Notes Immunohistochemistry on Paraffin Sections: 1/50 for 30 min at RT. Staining of formalin-fixed tissues requires boiling tissue sections in in EDTA buffer, pH 8.0for 10 min followed by cooling at RT for 20 min. Slides must be washed in between steps. Rinse slides with PBS/0.05 % Tween. Positive Control: Tonsil and reactive lymph node.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-ICOS Antibody Target Details ICOS Application Details Images back to top
Format Liquid
Buffer PBS, pH 7.6 with 1 % BSA as stabilizer and 0.09 % Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice DO NOT FREEZE!
Storage 4 °C
Storage Comment Store the antibody undiluted at 2-8 °C.

Images

Product Details anti-ICOS Antibody Target Details ICOS Application Details Handling back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-ICOS antibody (Inducible T-Cell Co-Stimulator) (C-Term) (ABIN492678) anti-Inducible T-Cell Co-Stimulator (ICOS) (C-Term) antibody