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anti-Human IL17A antibody for Immunohistochemistry

Recommended IL17A Antibody (supplied by: Log in to see )

Antigen
Interleukin 17A (IL17A) Antibodies
  • ChIL-17
  • Ctla-8
  • CTLA-8
  • CTLA8
  • Ctla8
  • IL-17
  • IL-17A
  • IL-17F
  • IL17
  • Il17
  • IL17A
Epitope
AA 20-155
31
30
15
15
15
14
14
11
9
8
7
6
6
4
4
4
3
2
2
1
1
1
1
1
Reactivity
Human
429
189
63
10
5
5
1
Host
Goat
244
209
101
48
8
3
1
Clonality
Polyclonal
Conjugate
This IL17A antibody is un-conjugated
70
35
32
24
17
15
15
12
10
10
8
7
7
7
7
7
7
5
5
5
4
4
4
3
3
2
2
2
2
2
2
2
1
1
Application
Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunohistochemistry (IHC), Immunoprecipitation (IP), Neutralization (Neut), Western Blotting (WB)
345
314
200
58
42
41
24
21
15
11
9
9
9
8
8
6
5
4
4
3
2
2
2
2
1
1
1
1
1
1
1
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Catalog No. ABIN4900592
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.001164044 ABIN3021082 IF IHC WB Rabbit IgG Log in to see Polyclonal 2
0.001164044 ABIN1102456 IHC ELISA WB Biotin Rabbit IgG Log in to see Polyclonal
0.001164044 ABIN1584596 IHC ELISA WB Rabbit N-Term Log in to see Polyclonal
0.001164044 ABIN1873195 IF IHC WB Rabbit IgG Log in to see Polyclonal
0.001164044 ABIN1873196 IP IHC WB Rabbit IgG Log in to see Polyclonal
0.001164044 ABIN1686096 Neut IHC ELISA WB Rabbit IgG Log in to see Polyclonal
0.001164044 ABIN465126 IHC Neut ELISA WB Goat Log in to see Polyclonal
0.001164044 ABIN1102457 IHC ELISA WB HRP Rabbit IgG Log in to see Polyclonal
0.001164044 ABIN2665119 Dep FACS IHC Mouse IgG1 kappa Log in to see BL23 5
0.001164044 ABIN2145073 ELISpot FACS IHC ELISA Mouse IgG1 Log in to see 4AeBio64CAP17
0.001164044 ABIN2145072 ELISpot FACS IHC ELISA Mouse IgG1 Log in to see 4AeBio64CAP17
0.001164044 ABIN2290015 IHC ELISA WB HRP Rabbit IgG Log in to see Polyclonal
0.001164044 ABIN2290019 IHC ELISA WB Biotin Rabbit IgG Log in to see Polyclonal
0.001164044 ABIN1087617 IHC ELISA WB Rabbit IgG Log in to see Polyclonal
0.001164044 ABIN1087618 IHC ELISA WB Rabbit IgG Log in to see Polyclonal
0.001164044 ABIN2697637 IF IHC WB Rabbit IgG Log in to see Polyclonal
0.001164044 ABIN2451283 Neut IHC ELISA Rabbit IgG Log in to see Polyclonal
0.001164044 ABIN2746794 CM ICC IF IHC ELISA WB FITC Rabbit IgG Log in to see Polyclonal
0.001164044 ABIN2403654 IF IHC WB Rabbit IgG Log in to see Polyclonal
0.001164044 ABIN2290000 Neut IHC ELISA WB Goat IgG Log in to see Polyclonal

Top referenced anti-IL17A antibody for Immunohistochemistry

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Application / Reactivity Human
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General

Antigen Interleukin 17A (IL17A) Antibodies
Epitope AA 20-155
(31), (30), (15), (15), (15), (14), (14), (11), (9), (8), (7), (6), (6), (4), (4), (4), (3), (2), (2), (1), (1), (1), (1), (1)
Reactivity Human
(429), (189), (63), (10), (5), (5), (1)
Host Goat
(244), (209), (101), (48), (8), (3), (1)
Clonality
Polyclonal
Conjugate This IL17A antibody is un-conjugated
(70), (35), (32), (24), (17), (15), (15), (12), (10), (10), (8), (7), (7), (7), (7), (7), (7), (5), (5), (5), (4), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1)
Application Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunohistochemistry (IHC), Immunoprecipitation (IP), Neutralization (Neut), Western Blotting (WB)
(345), (314), (200), (58), (42), (41), (24), (21), (15), (11), (9), (9), (9), (8), (8), (6), (5), (4), (4), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Pubmed 20 references available
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Product Details anti-IL17A Antibody

Target Details IL17A Application Details Handling References for anti-IL17A Antibody (ABIN4900592) Images
Specificity Detects human IL-17 in direct ELISAs and Western blots. In direct ELISAs, approximately 60 % cross-reactivity with recombinant canine IL-17 is observed, approximately 10 % cross-reactivity with recombinant human (rh) IL-17F and with recombinant mouse IL-17 is observed, and less than 1 % cross-reactivity with rhIL-17B, rhIL-17C, rhIL-17D, and rhIL-17E is observed.
Purification Antigen Affinity-purified
Sterility 0.2 μm filtered
Endotoxin Level <0.10 EU per 1 g of the antibody by the LAL method.
Immunogen E. coli-derived recombinant human IL-17, Ile20-Ala155, Accession # Q16552
Isotype IgG

Target Details IL17A

Product Details anti-IL17A Antibody Application Details Handling References for anti-IL17A Antibody (ABIN4900592) Images back to top
Antigen
Alternative Name IL-17/IL-17A (IL17A Antibody Abstract)
Gene ID 3605
UniProt Q16552
Pathways TCR Signaling

Application Details

Product Details anti-IL17A Antibody Target Details IL17A Handling References for anti-IL17A Antibody (ABIN4900592) Images back to top
Application Notes Western Blot 1 μg/mL, Immunohistochemistry 1-15 μg/mL, Immunoprecipitation 3 μg/100 μg cell lysate, Neutralization 0.02-0.12 μg/mL, Intracellular Staining by Flow Cytometry 2.5 μg/10^6 cells, Immunocytochemistry 5-15 μg/mL, CyTOF-ready
Restrictions For Research Use only

Handling

Product Details anti-IL17A Antibody Target Details IL17A Application Details References for anti-IL17A Antibody (ABIN4900592) Images back to top
Reconstitution Reconstitute at 0.2 mg/mL in sterile PBS.
Buffer 0.2 m filtered solution in PBS with Trehalose.
Preservative Without preservative
Storage 4 °C/-20 °C/-80 °C
Storage Comment Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 C as supplied. 1 month, 2 to 8 C under sterile conditions after reconstitution. 6 months, -20 to -70 C under sterile conditions after reconstitution.
Expiry Date 12 months

References for anti-IL17A Antibody (ABIN4900592)

Product Details anti-IL17A Antibody Target Details IL17A Application Details Handling Images back to top
Product cited in:

Millar, Akbar, Campbell, Reilly, Kerr, McLean, Frleta-Gilchrist, Fazzi, Leach, Rooney, Crowe, Murrell, McInnes: "IL-17A mediates inflammatory and tissue remodelling events in early human tendinopathy." in: Scientific reports, Vol. 6, pp. 27149, 2016 Method employed by authors: Immunohistochemistry (IHC) (Sample species: Human).

Fattahi, Brandsma, Lodewijk, Reinders-Luinge, Postma, Timens, Hylkema, Ten Hacken: "Atopy and Inhaled Corticosteroid Use Associate with Fewer IL-17+ Cells in Asthmatic Airways." in: PLoS ONE, Vol. 11, Issue 8, pp. e0161433, 2016 Method employed by authors: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Sample species: Human).

Mariuzzi, Domenis, Orsaria, Marzinotto, Londero, Bulfoni, Candotti, Zanello, Ballico, Mimmi, Calcagno, Marchesoni, Di Loreto, Beltrami, Cesselli, Gri: "Functional expression of aryl hydrocarbon receptor on mast cells populating human endometriotic tissues." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 96, Issue 9, pp. 959-71, 2016 Method employed by authors: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Sample species: Human).

Nussbaumer-Ochsner, Stolk, Ferraz da Silva, van Schadewijk, de Jeu, Prins, Mauad, Rabe, Hiemstra: "Association of Lung Inflammatory Cells with Small Airways Function and Exhaled Breath Markers in Smokers - Is There a Specific Role for Mast Cells?" in: PLoS ONE, Vol. 10, Issue 6, pp. e0129426, 2015 Method employed by authors: Immunohistochemistry (IHC) (Sample species: Human).

Martin, Kesselring, Saidou, Brunner, Schiechl, Mouris, Wege, Rümmele, Schlitt, Geissler, Fichtner-Feigl: "RORγt(+) hematopoietic cells are necessary for tumor cell proliferation during colitis-associated tumorigenesis in mice." in: European journal of immunology, Vol. 45, Issue 6, pp. 1667-79, 2015 Method employed by authors: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Sample species: Human).

Punt, Houwing-Duistermaat, Schulkens, Thijssen, Osse, de Kroon, Griffioen, Fleuren, Gorter, Jordanova: "Correlations between immune response and vascularization qRT-PCR gene expression clusters in squamous cervical cancer." in: Molecular cancer, Vol. 14, pp. 71, 2015 Method employed by authors: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Sample species: Human).

Chang, Al-Alwan, Alshakfa, Audusseau, Mogas, Chouiali, Nair, Baglole, Hamid, Eidelman: "Upregulation of IL-17A/F from human lung tissue explants with cigarette smoke exposure: implications for COPD." in: Respiratory research, Vol. 15, pp. 145, 2015 Method employed by authors: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Sample species: Human).

Liu, Jin, Zhang, Lin, Chen, Sun, Zhang, Zhang, Yu: "Intratumor IL-17-positive mast cells are the major source of the IL-17 that is predictive of survival in gastric cancer patients." in: PLoS ONE, Vol. 9, Issue 9, pp. e106834, 2014 Method employed by authors: Immunohistochemistry (IHC) (Sample species: Human).

Keijsers, Hendriks, van Erp, van Cranenbroek, van de Kerkhof, Koenen, Joosten: "In vivo induction of cutaneous inflammation results in the accumulation of extracellular trap-forming neutrophils expressing RORγt and IL-17." in: The Journal of investigative dermatology, Vol. 134, Issue 5, pp. 1276-84, 2014 Method employed by authors: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Sample species: Human).

Hendriks, van der Velden, Wolberink, Seyger, Schalkwijk, Zeeuwen, de Jong, Pasch, van Erp, van de Kerkhof: "The effect of adalimumab on key drivers in the pathogenesis of psoriasis." in: The British journal of dermatology, Vol. 170, Issue 3, pp. 571-80, 2014 Method employed by authors: Immunohistochemistry (IHC) (Sample species: Human).

Shimizu, Tasaki, Sano, Ju, Nishihara, Oishi, Koga, Kawai, Kanda: "Sera from remitting and secondary progressive multiple sclerosis patients disrupt the blood-brain barrier." in: PLoS ONE, Vol. 9, Issue 3, pp. e92872, 2014 Method employed by authors: Neutralization (Neut) (Sample species: Human).

Todd, Simpson, Estis, Torres, Wub: "Reference range and short- and long-term biological variation of interleukin (IL)-6, IL-17A and tissue necrosis factor-alpha using high sensitivity assays." in: Cytokine, Vol. 64, Issue 3, pp. 660-5, 2013 Method employed by authors: ELISA (ELISA) (Sample species: Human).

Lotti, Jarrar, Pai, Hitomi, Lathia, Mace, Gantt, Sukhdeo, DeVecchio, Vasanji, Leahy, Hjelmeland, Kalady, Rich: "Chemotherapy activates cancer-associated fibroblasts to maintain colorectal cancer-initiating cells by IL-17A." in: The Journal of experimental medicine, Vol. 210, Issue 13, pp. 2851-72, 2013 Method employed by authors: Immunofluorescence (IF) (Sample species: Human).

Truchetet, Brembilla, Montanari, Lonati, Raschi, Zeni, Fontao, Meroni, Chizzolini: "Interleukin-17A+ cell counts are increased in systemic sclerosis skin and their number is inversely correlated with the extent of skin involvement." in: Arthritis and rheumatism, Vol. 65, Issue 5, pp. 1347-56, 2013 Method employed by authors: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Sample species: Human).

Xing, Yang, Yang, Wei, Zhu, Gao, Li: "IL-17A induces endothelial inflammation in systemic sclerosis via the ERK signaling pathway." in: PLoS ONE, Vol. 8, Issue 12, pp. e85032, 2013 Method employed by authors: Neutralization (Neut) (Sample species: Human).

Gelderblom, Weymar, Bernreuther, Velden, Arunachalam, Steinbach, Orthey, Arumugam, Leypoldt, Simova, Thom, Friese, Prinz, Hölscher, Glatzel, Korn, Gerloff, Tolosa, Magnus: "Neutralization of the IL-17 axis diminishes neutrophil invasion and protects from ischemic stroke." in: Blood, Vol. 120, Issue 18, pp. 3793-802, 2012 Method employed by authors: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Sample species: Human).

Fontao, Brembilla, Masouyé, Kaya, Prins, Dupin, Saurat, Chizzolini, Piguet: "Interleukin-17 expression in neutrophils and Th17 cells in cutaneous T-cell lymphoma associated with neutrophilic infiltrate of the skin." in: The British journal of dermatology, Vol. 166, Issue 3, pp. 687-9, 2012 Method employed by authors: Immunohistochemistry (IHC) (Sample species: Human).

Droeser, Zlobec, Kilic, Güth, Heberer, Spagnoli, Oertli, Tapia: "Differential pattern and prognostic significance of CD4+, FOXP3+ and IL-17+ tumor infiltrating lymphocytes in ductal and lobular breast cancers." in: BMC cancer, Vol. 12, pp. 134, 2012 Method employed by authors: Immunohistochemistry (IHC) (Sample species: Human).

Liu, Lee, McManus, Choy: "Induction of endothelial nitric oxide synthase expression by IL-17 in human vascular endothelial cells: implications for vascular remodeling in transplant vasculopathy." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 188, Issue 3, pp. 1544-50, 2012 Method employed by authors: Immunohistochemistry (IHC) (Sample species: Human).

Lapinski, Kwon, Lubeck, Wilkinson, Srinivasan, Sevick-Muraca, King: "RASA1 maintains the lymphatic vasculature in a quiescent functional state in mice." in: The Journal of clinical investigation, Vol. 122, Issue 2, pp. 733-47, 2012 Method employed by authors: Neutralization (Neut) (Sample species: Human).

Images

Product Details anti-IL17A Antibody Target Details IL17A Application Details Handling References for anti-IL17A Antibody (ABIN4900592) back to top
Supplier Images
Neutralization (Neut) image for anti-IL17A antibody (Interleukin 17A) (AA 20-155) (ABIN4900592) IL-6 Secretion Induced by IL-17 and Neutralization by Human IL-17 Antibody.
Flow Cytometry (FACS) image for anti-IL17A antibody (Interleukin 17A) (AA 20-155) (ABIN4900592) Detection of IL-17 in Human PBMCs by Flow Cytometry.
Immunohistochemistry (IHC) image for anti-IL17A antibody (Interleukin 17A) (AA 20-155) (ABIN4900592) IL-17/IL-17A in Human Tonsil. IL-17/IL-17A was detected in immersion fixed paraffin-e...
Immunoprecipitation (IP) image for anti-IL17A antibody (Interleukin 17A) (AA 20-155) (ABIN4900592) Immunoprecipitation of Human IL-17.
Western Blotting (WB) image for anti-IL17A antibody (Interleukin 17A) (AA 20-155) (ABIN4900592) Detection of Human IL-17 by Western Blot.