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anti-Human IL17A antibody for Neutralization

Recommended IL17A Antibody (supplied by: Log in to see )

Antigen
Interleukin 17A (IL17A) Antibodies
  • ChIL-17
  • Ctla-8
  • CTLA-8
  • CTLA8
  • Ctla8
  • IL-17
  • IL-17A
  • IL-17F
  • IL17
  • Il17
  • IL17A
Reactivity
Human
305
174
54
10
5
5
1
Host
Rabbit
200
128
96
42
8
3
1
Clonality
Polyclonal
Conjugate
This IL17A antibody is un-conjugated
63
31
26
18
17
9
7
6
6
6
4
3
3
2
2
2
2
2
2
2
2
2
2
2
1
Application
Enzyme Immunoassay (EIA), Neutralization (Neut), Western Blotting (WB)
251
249
138
42
38
27
24
22
19
14
11
10
9
9
9
8
7
6
5
4
4
2
2
2
2
2
1
1
1
1
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Catalog No. ABIN401101
$ 253.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.00087858096 ABIN401100 EIA Neut WB Rabbit IgG Log in to see Polyclonal 3
0.00087858096 ABIN282544 ELISA (Capture) ELISPOT (Capture) Neut Mouse IgG1 kappa Log in to see 64CAP17 1
0.00087858096 ABIN1686096 Neut IHC ELISA WB Rabbit IgG Log in to see Polyclonal
0.00087858096 ABIN1686097 Neut ELISA WB Rabbit IgG Log in to see Polyclonal
0.00087858096 ABIN1102463 IHC (p) Neut ELISA WB Rabbit IgG Log in to see Polyclonal
0.00087858096 ABIN181572 EIA IHC (p) Neut WB Goat Log in to see Polyclonal
0.00087858096 ABIN465126 IHC Neut ELISA WB Goat Log in to see Polyclonal
0.00087858096 ABIN786714 Neut Mouse IgG1 Log in to see 403D10-01 6
0.00087858096 ABIN2472055 Neut ELISA WB Biotin Mouse IgG2b, kappa full length Log in to see Polyclonal
0.00087858096 ABIN290358 ICC FACS Neut ELISA WB Goat IgG Log in to see Polyclonal
0.00087858096 ABIN2472054 Neut ELISA WB Mouse IgG2b, kappa full length Log in to see Polyclonal
0.00087858096 ABIN2451283 Neut IHC ELISA Rabbit IgG Log in to see Polyclonal
0.00087858096 ABIN2287945 IC FACS IP Neut ELISA WB Goat IgG AA 20-155 Log in to see Polyclonal
0.00087858096 ABIN2290000 Neut IHC ELISA WB Goat IgG Log in to see Polyclonal
0.00087858096 ABIN2287922 Neut ELISA WB HRP Rabbit IgG Log in to see Polyclonal
0.00087858096 ABIN2287924 Neut ELISA WB PE Rabbit IgG Log in to see Polyclonal
0.00087858096 ABIN2287968 Neut ELISA WB Alkaline Phosphatase (AP) Rabbit IgG Log in to see Polyclonal
0.00087858096 ABIN2287972 Neut ELISA WB Biotin Rabbit IgG Log in to see Polyclonal
0.00087858096 ABIN2287971 Neut ELISA WB APC Rabbit IgG Log in to see Polyclonal
0.00087858096 ABIN2287974 Neut ELISA WB FITC Rabbit IgG Log in to see Polyclonal

Top referenced anti-IL17A antibody for Neutralization

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Application / Reactivity Human
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Blocking Antibody (Inhibition) 3 Antibodies
Blocking Reagent (BR) 2 Antibodies
Confocal Microscopy (CM) 2 Antibodies
Depletion (Dep) 1 Antibodies
ELISA 148 Antibodies
ELISA (Capture) 7 Antibodies
ELISA (Detection) 8 Antibodies
ELISpot 9 Antibodies
ELISpot (Capture) (ELISPOT (Capture)) 3 Antibodies
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General

Antigen Interleukin 17A (IL17A) Antibodies
Reactivity Human
(305), (174), (54), (10), (5), (5), (1)
Host Rabbit
(200), (128), (96), (42), (8), (3), (1)
Clonality
Polyclonal
Conjugate This IL17A antibody is un-conjugated
(63), (31), (26), (18), (17), (9), (7), (6), (6), (6), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1)
Application Enzyme Immunoassay (EIA), Neutralization (Neut), Western Blotting (WB)
(251), (249), (138), (42), (38), (27), (24), (22), (19), (14), (11), (10), (9), (9), (9), (8), (7), (6), (5), (4), (4), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Pubmed 3 references available
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Product Details anti-IL17A Antibody

Target Details IL17A Application Details Handling References for anti-IL17A Antibody (ABIN401101) Images
Specificity This antibody will recognize both native and recombinant human IL17-A in cell supernatants and certain body fluids.
Purification Purified
Immunogen Recombinant human IL17-A protein
Isotype IgG

Target Details IL17A

Product Details anti-IL17A Antibody Application Details Handling References for anti-IL17A Antibody (ABIN401101) Images back to top
Antigen
Alternative Name Interleukin-17A (IL17A) (IL17A Antibody Abstract)
Background IL17-A (also known as Interleukin-17, Cytotoxic T-lymphocyte-associated antigen 8 and CTLA-8 in rodents) is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NFkappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. IL17-A is the founding member of a group of cytokines called the IL-17 family. IL17-A was originally identified as a transcript from a rodent T-cell hybridoma. To elicit its functions, IL17 binds to a type I cell surface receptor called IL17R of which there are at least three variants IL17RA, IL17RB, and IL17RC.Synonyms: CTLA-8, CTLA8, Cytotoxic T-lymphocyte-associated antigen 8, IL-17, IL-17A, IL17
Gene ID 3605
NCBI Accession NP_002181
UniProt Q16552
Research Area Cytokines, Receptors, Inflammation, Immunology, Virology, Cancer
Pathways TCR Signaling

Application Details

Product Details anti-IL17A Antibody Target Details IL17A Handling References for anti-IL17A Antibody (ABIN401101) Images back to top
Application Notes ELISA: 1/20000 - 1/100000. Western Blot: 1/500 - 1/2000. Neutralization: 1/400.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-IL17A Antibody Target Details IL17A Application Details References for anti-IL17A Antibody (ABIN401101) Images back to top
Format Liquid
Reconstitution Restore with 0.1 mL of deionized water (or equivalent).
Concentration 1.0 mg/mL (by UV absorbance at 280 nm)
Buffer 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Prior to reconstitution store at 2-8 °C. Following reconstitution store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

References for anti-IL17A Antibody (ABIN401101)

Product Details anti-IL17A Antibody Target Details IL17A Application Details Handling Images back to top
Background publications

Yin, Wen, Li, Wang: "Hypoxia enhances stimulating effect of amyloid beta peptide (25-35) for interleukin 17 and T helper lymphocyte subtype 17 upregulation in cultured peripheral blood mononuclear cells." in: Microbiology and immunology, Vol. 53, Issue 5, pp. 281-6, 2009

Paust, Turner, Steinmetz, Peters, Heymann, Hölscher, Wolf, Kurts, Mittrücker, Stahl, Panzer: "The IL-23/Th17 axis contributes to renal injury in experimental glomerulonephritis." in: Journal of the American Society of Nephrology : JASN, Vol. 20, Issue 5, pp. 969-79, 2009

Shin, Shin, Noh: "Interleukin-17A inhibits adipocyte differentiation in human mesenchymal stem cells and regulates pro-inflammatory responses in adipocytes." in: Biochemical pharmacology, Vol. 77, Issue 12, pp. 1835-44, 2009

Images

Product Details anti-IL17A Antibody Target Details IL17A Application Details Handling References for anti-IL17A Antibody (ABIN401101) back to top
Supplier Images
 image for anti-IL17A antibody (Interleukin 17A) (ABIN401101) anti-Interleukin 17A (IL17A) antibody