anti-Mouse (Murine) IL17A antibody for Neutralization

Recommended IL17A Antibody (supplied by: Log in to see )

Antigen
Interleukin 17A (IL17A) Antibodies
  • Il17
  • IL17A
  • CTLA8
  • IL-17
  • IL-17A
  • IL17
  • Ctla-8
  • Ctla8
  • CTLA-8
  • ChIL-17
  • IL-17F
  • interleukin 17A
  • interleukin 17A-like
  • interleukin 17F
  • Il17a
  • IL17A
  • LOC100339322
  • IL17F
Epitope
AA 22-158
27
24
13
12
11
9
9
7
7
6
4
4
3
3
2
2
1
1
1
1
1
1
Reactivity
Mouse (Murine)
374
132
41
7
7
5
3
3
2
2
Host
Goat
248
134
77
39
3
3
Clonality
Polyclonal
Conjugate
This IL17A antibody is un-conjugated
56
32
27
20
16
15
15
12
11
11
10
7
7
7
7
7
5
5
5
4
4
4
4
4
4
3
2
2
1
Application
Cytometry by Time of Flight (CyTOF), Flow Cytometry (FACS), Neutralization (Neut), Western Blotting (WB)
269
229
194
44
29
20
19
16
8
8
8
7
6
6
6
4
4
4
3
3
2
1
1
1
1
1
1
1
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Catalog No. ABIN4899637
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN1177292 ICS Neut ELISA Rat IgG1, kappa Log in to see TC11-18H10 3
1 ABIN2689741 Inhibition Neut ELISA WB Rat IgG1, kappa Log in to see TC11 2
1 ABIN959225 Neut Rat IgG1, kappa Log in to see TC11-18H10
1 ABIN218197 FACS IF Neut ELISA WB Rat IgG1, kappa Log in to see
1 ABIN2689742 Inhibition Neut ELISA WB Rat IgG1, kappa Log in to see TC11

General

Antigen Interleukin 17A (IL17A) Antibodies
Epitope AA 22-158
(27), (24), (13), (12), (11), (9), (9), (7), (7), (6), (4), (4), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1)
Reactivity Mouse (Murine)
(374), (132), (41), (7), (7), (5), (3), (3), (2), (2)
Host Goat
(248), (134), (77), (39), (3), (3)
Clonality
Polyclonal
Conjugate This IL17A antibody is un-conjugated
(56), (32), (27), (20), (16), (15), (15), (12), (11), (11), (10), (7), (7), (7), (7), (7), (5), (5), (5), (4), (4), (4), (4), (4), (4), (3), (2), (2), (1)
Application Cytometry by Time of Flight (CyTOF), Flow Cytometry (FACS), Neutralization (Neut), Western Blotting (WB)
(269), (229), (194), (44), (29), (20), (19), (16), (8), (8), (8), (7), (6), (6), (6), (4), (4), (4), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1)
Pubmed 10 references available
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Product Details anti-IL17A Antibody

Target Details IL17A Application Details Handling ProductDetails: References for anti-IL17A antibody (ABIN4899637) Images
Specificity Detects mouse and rat IL-17 in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 10 % cross-reactivity with recombinant human IL-17A and recombinant mouse (rm) IL-17F is observed and less than 1 % cross-reactivity with rmIL-17B, rmIL-17C, rmIL-17D, and rmIL-17E is observed.
Purification Immunogen affinity purified
Sterility 0.2 μm filtered
Endotoxin Level <0.10 EU per 1 μg of the antibody by the LAL method.
Immunogen E. coli-derived recombinant mouse IL-17, Thr22-Ala158, Accession # Q62386
Isotype IgG

Target Details IL17A

Product Details anti-IL17A Antibody Application Details Handling ProductDetails: References for anti-IL17A antibody (ABIN4899637) Images back to top
Antigen
Alternative Name IL-17/IL-17A (IL17A Antibody Abstract)
Background Alternative Names: CTLA-8, CTLA8cytotoxic T-lymphocyte-associated serine esterase 8, Cytotoxic T-lymphocyte-associated antigen 8, IL17, IL17A, IL-17A, IL-17Acytotoxic T-lymphocyte-associated protein 8, IL-17CTLA-8, IL17interleukin-17A, interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8), interleukin 17A
Gene ID 3605
UniProt Q62386

Application Details

Product Details anti-IL17A Antibody Target Details IL17A Handling ProductDetails: References for anti-IL17A antibody (ABIN4899637) Images back to top
Application Notes Western Blot 0.1 μg/mL
Neutralization 0.05-0.25 μg/mL
Intracellular Staining by Flow Cytometry 2.5 μg/10^6 cells
CyTOF-ready
Restrictions For Research Use only

Handling

Product Details anti-IL17A Antibody Target Details IL17A Application Details ProductDetails: References for anti-IL17A antibody (ABIN4899637) Images back to top
Reconstitution Reconstitute at 0.2 mg/mL in sterile PBS.
Buffer Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Preservative Without preservative
Storage 4 °C,-20 °C,-80 °C
Storage Comment Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt,-20°C to -70°C as supplied. 1 month,2°C to 8°C under sterile conditions after reconstitution. 6 months,-20°C to -70°C under sterile conditions after reconstitution.
Expiry Date 12 months

ProductDetails: References for anti-IL17A antibody (ABIN4899637)

Product Details anti-IL17A Antibody Target Details IL17A Application Details Handling Images back to top
Product cited in:

Benevides, da Fonseca, Donate, Tiezzi, De Carvalho, de Andrade, Martins, Silva: "IL17 Promotes Mammary Tumor Progression by Changing the Behavior of Tumor Cells and Eliciting Tumorigenic Neutrophils Recruitment." in: Cancer research, Vol. 75, Issue 18, pp. 3788-99, 2015 Method employed by authors: In vivo Studies (in vivo) (Sample species: Mouse (Murine)).

Carmi, Rinott, Dotan, Elkabets, Rider, Voronov, Apte: "Microenvironment-derived IL-1 and IL-17 interact in the control of lung metastasis." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 186, Issue 6, pp. 3462-71, 2011 Method employed by authors: In vivo Studies (in vivo) (Sample species: Mouse (Murine)).

Li, Burns, Han, Rumbaut, Smith: "IL-17 and VEGF are necessary for efficient corneal nerve regeneration." in: The American journal of pathology, Vol. 178, Issue 3, pp. 1106-16, 2011 Method employed by authors: In vivo Studies (in vivo) (Sample species: Mouse (Murine)).

Otani, Watanabe, Tanigawa, Okazaki, Yamagami, Watanabe, Tominaga, Fujiwara, Oshitani, Arakawa: "Anti-inflammatory effects of IL-17A on Helicobacter pylori-induced gastritis." in: Biochemical and biophysical research communications, Vol. 382, Issue 2, pp. 252-8, 2009 Method employed by authors: Immunohistochemistry (IHC) (Sample species: Mouse (Murine)).

Yuan, Ansari, DAddio, Paez-Cortez, Schmitt, Donnarumma, Boenisch, Zhao, Popoola, Clarkson, Yagita, Akiba, Freeman, Iacomini, Turka, Glimcher, Sayegh: "Targeting Tim-1 to overcome resistance to transplantation tolerance mediated by CD8 T17 cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 26, pp. 10734-9, 2009 Method employed by authors: Immunohistochemistry (Frozen Sections) (IHC (fro)) (Sample species: Mouse (Murine)).

Lemos, Grespan, Vieira, Cunha, Verri, Fernandes, Souto, McInnes, Ferreira, Liew, Cunha: "Prostaglandin mediates IL-23/IL-17-induced neutrophil migration in inflammation by inhibiting IL-12 and IFNgamma production." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 14, pp. 5954-9, 2009 Method employed by authors: In vivo Studies (in vivo) (Sample species: Mouse (Murine)).

Muranski, Boni, Antony, Cassard, Irvine, Kaiser, Paulos, Palmer, Touloukian, Ptak, Gattinoni, Wrzesinski, Hinrichs, Kerstann, Feigenbaum, Chan, Restifo: "Tumor-specific Th17-polarized cells eradicate large established melanoma." in: Blood, Vol. 112, Issue 2, pp. 362-73, 2008 Method employed by authors: In vivo Studies (in vivo) (Sample species: Mouse (Murine)).

Venkatachalam, Mummidi, Cortez, Prabhu, Valente, Chandrasekar: "Resveratrol inhibits high glucose-induced PI3K/Akt/ERK-dependent interleukin-17 expression in primary mouse cardiac fibroblasts." in: American journal of physiology. Heart and circulatory physiology, Vol. 294, Issue 5, pp. H2078-87, 2008 Method employed by authors: Western Blotting (WB) (Sample species: Mouse (Murine)).

Gocke, Cravens, Ben, Hussain, Northrop, Racke, Lovett-Racke: "T-bet regulates the fate of Th1 and Th17 lymphocytes in autoimmunity." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 178, Issue 3, pp. 1341-8, 2007 Method employed by authors: Western Blotting (WB) (Sample species: Mouse (Murine)).

Ferretti, Bonneau, Dubois, Jones, Trifilieff: "IL-17, produced by lymphocytes and neutrophils, is necessary for lipopolysaccharide-induced airway neutrophilia: IL-15 as a possible trigger." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 170, Issue 4, pp. 2106-12, 2003 Method employed by authors: In vivo Studies (in vivo) (Sample species: Mouse (Murine)).

Images

Product Details anti-IL17A Antibody Target Details IL17A Application Details Handling ProductDetails: References for anti-IL17A antibody (ABIN4899637) back to top
Supplier Images
Neutralization (Neut) image for anti-Interleukin 17A (IL17A) (AA 22-158) antibody (ABIN4899637) IL-6 Secretion Induced by IL-17 and Neutralization by Mouse IL-17 Antibody. Recombina...
Flow Cytometry (FACS) image for anti-Interleukin 17A (IL17A) (AA 22-158) antibody (ABIN4899637) Detection of IL-17 in EL-4 Mouse Cell Line by Flow Cytometry. EL-4 mouse lymphoblast ...
Flow Cytometry (FACS) image for anti-Interleukin 17A (IL17A) (AA 22-158) antibody (ABIN4899637) Detection of IL-17 in EL-4 Mouse Cell Line by Flow Cytometry. EL-4 mouse lymphoblast ...
Neutralization (Neut) image for anti-Interleukin 17A (IL17A) (AA 22-158) antibody (ABIN4899637) IL-6 Secretion Induced by IL-17 and Neutralization by Mouse IL-17 Antibody. Recombina...