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anti-Rat (Rattus) IL17A antibody for Neutralization

Recommended IL17A Antibody (supplied by: Log in to see )

Antigen
Interleukin 17A (IL17A) Antibodies
  • ChIL-17
  • Ctla-8
  • CTLA-8
  • CTLA8
  • Ctla8
  • IL-17
  • IL-17A
  • IL-17F
  • IL17
  • Il17
  • IL17A
Reactivity
Rat (Rattus)
431
194
71
10
5
5
1
Host
Rabbit
248
206
111
44
8
3
1
Clonality
Polyclonal
Conjugate
This IL17A antibody is un-conjugated
71
34
34
24
17
16
14
11
8
7
7
7
7
7
7
7
7
7
6
6
5
5
4
3
3
3
2
2
2
2
2
2
2
2
2
1
1
Application
Immunohistochemistry (IHC), Neutralization (Neut), Radioimmunoassay (RIA), ELISA, Western Blotting (WB)
344
311
193
58
43
41
24
22
19
15
11
10
9
9
9
8
7
6
5
4
4
3
2
2
2
2
2
1
1
1
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Catalog No. ABIN349633
$ 369.00
Plus shipping costs $45.00

Similar anti-IL17A Antibodies

Application / Reactivity Rat (Rattus)
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ELISA 24 Antibodies
ELISA (Detection) 1 Antibodies
ELISpot (Detection) (ELISPOT (Detection)) 1 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies
Flow Cytometry (FACS) 27 Antibodies
Immunocytochemistry (ICC) 4 Antibodies
Immunofluorescence (IF) 5 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies
Immunohistochemistry (IHC) 14 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 2 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 5 Antibodies
Intracellular Staining (ICS) 9 Antibodies
Neutralization (Neut) 1 Antibodies
Radioimmunoassay (RIA) 1 Antibodies
Western Blotting (WB) 44 Antibodies

General

Antigen Interleukin 17A (IL17A) Antibodies
Reactivity Rat (Rattus)
(431), (194), (71), (10), (5), (5), (1)
Host Rabbit
(248), (206), (111), (44), (8), (3), (1)
Clonality
Polyclonal
Conjugate This IL17A antibody is un-conjugated
(71), (34), (34), (24), (17), (16), (14), (11), (8), (7), (7), (7), (7), (7), (7), (7), (7), (7), (6), (6), (5), (5), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1)
Application Immunohistochemistry (IHC), Neutralization (Neut), Radioimmunoassay (RIA), ELISA, Western Blotting (WB)
(344), (311), (193), (58), (43), (41), (24), (22), (19), (15), (11), (10), (9), (9), (9), (8), (7), (6), (5), (4), (4), (3), (2), (2), (2), (2), (2), (1), (1), (1)
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Product Details anti-IL17A Antibody

Target Details IL17A Application Details Handling Images
Cross-Reactivity Mouse (Murine)
Characteristics Concentration Definition: by UV absorbance at 280 nm
Immunogen This purified antibody was prepared from whole rabbit serum produced by repeated immunizations with full length recombinant rat IL17-A protein.
Immunogentype:Recombinant
Isotype IgG

Target Details IL17A

Product Details anti-IL17A Antibody Application Details Handling Images back to top
Antigen
Alternative Name IL-17A (IL17A Antibody Abstract)
Background Rat IL17-A (also known as Interleukin-17, Cytotoxic T-lymphocyte-associated antigen 8 and CTLA-8) is a proinflammatory cytokine member of a six-species family of proteins (IL-17A-17F). Rat IL-17A protein is a homodimer consisting of two 134 amino acids peptides. IL-17A is secreted mainly by activated CD4+ and CD8+ T lymphocytes and acts through its receptor, IL-17R, to induce the expression of many mediators of inflammation, most strikingly, those that are involved in the proliferation, maturation and chemotaxis of neutrophils. Elevated levels of IL-17A have been associated with several conditions, including rheumatoid arthritis, airway inflammation, allograft rejection, inflammatory bowel disease, psoriasis, cancer and multiple sclerosis. There is 58% identity between the amino acid sequence of human and rat IL-17A.
Synonyms: Interleukin-17, Cytotoxic T-lymphocyte-associated antigen 8 and CTLA-8
Gene ID 301289
UniProt Q61453
Pathways TCR Signaling

Application Details

Product Details anti-IL17A Antibody Target Details IL17A Handling Images back to top
Application Notes This purified antibody has been tested for use in ELISA and western blotting. Reactivity is also expected in neutralizations, radioimmunoassay and immunohistochemistry. The endotoxin content is estimated to be <10 pg/µl by the LAL method. The recombinant immunogen is a non-glycosylated homodimer joined by disulfide bonds having a molecular mass of 30.0 kDa. By western blot from a reducing gel expect a band approximately 15.0 kDa in size corresponding to rat IL17-A protein in the appropriate cell lysate or extract. Specific conditions for reactivity should be optimized by the end user.
Restrictions For Research Use only

Handling

Product Details anti-IL17A Antibody Target Details IL17A Application Details Images back to top
Format Lyophilized
Reconstitution Restore with deionized water (or equivalent)
Concentration 1.0 mg/mL
Buffer 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Storage 4 °C

Images

Product Details anti-IL17A Antibody Target Details IL17A Application Details Handling back to top
Supplier Images
Western Blotting (WB) image for anti-IL17A antibody (Interleukin 17A) (ABIN349633) Western blot using anti-IL-17A antibody shows detection of mouse recombinant IL-17A p...
 image for anti-IL17A antibody (Interleukin 17A) (ABIN349633) anti-Interleukin 17A (IL17A) antibody (Image 2)