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Mouse (Murine) IL17A Protein expressed in Escherichia coli (E. coli) - ABIN2667468
Ouyang, Kolls, Zheng: The biological functions of T helper 17 cell effector cytokines in inflammation. in Immunity 2008
Show all 10 references for ABIN2667468
Human IL17A Protein expressed in Escherichia coli (E. coli) - ABIN2667466
Yu, Gaffen: Interleukin-17: a novel inflammatory cytokine that bridges innate and adaptive immunity. in Frontiers in bioscience : a journal and virtual library 2007
Show all 7 references for ABIN2667466
Human IL17A Protein expressed in Escherichia coli (E. coli) - ABIN2667465
Rouvier, Luciani, Mattéi, Denizot, Golstein: CTLA-8, cloned from an activated T cell, bearing AU-rich messenger RNA instability sequences, and homologous to a herpesvirus saimiri gene. in Journal of immunology (Baltimore, Md. : 1950) 1993
Show all 7 references for ABIN2667465
Human IL17A Protein expressed in Escherichia coli (E. coli) - ABIN413453
Bérubé, Roussel, Nattagh, Rousseau et al.: Loss of cystic fibrosis transmembrane conductance regulator function enhances activation of p38 and ERK MAPKs, increasing interleukin-6 synthesis in airway epithelial cells exposed to Pseudomonas ... in The Journal of biological chemistry 2010
Show all 3 references for ABIN413453
Rat (Rattus) IL17A Protein expressed in Escherichia coli (E. coli) - ABIN413456
Arif, Moore, Marks, Bouckenooghe, Dayan, Planas, Vives-Pi, Powrie, Tree, Marchetti, Huang, Gurzov, Pujol-Borrell, Eizirik, Peakman: Peripheral and islet interleukin-17 pathway activation characterizes human autoimmune diabetes and promotes cytokine-mediated β-cell death. in Diabetes 2011
Data indicate that IL-17/22-producing cells play an important role in maintenance of intestinal mucosa in gluten-sensitive primates.
The potential pathogenic role of IL-17A-producing T cells in the inflammatory response and fibrosis of Thyroid-associated ophthalmopathy.
These findings suggest that IL-17A is an independent risk factor of non-proliferative diabetic retinopathy, and irisin (show FNDC5 Proteins) could protect against diabetic retinopathy through potential anti-IL-17A effects.
Th17 cells count and the serum IL-17 level were increased in patients with oral squamous cell carcinoma.
Vitreous fluid IL-17A levels were significantly elevated in patients with diabetic retinopathy compared with those of the control group.
PD-1 (show PDCD1 Proteins) is overexpressed in IL-17A-producing T cells in both imiquimod-treated mice and patients with psoriasis. Moreover, recombinant PD-L1 (show CD274 Proteins)-Fc alleviates psoriatic inflammation in imiquimod-treated mice.
BAFF (show TNFSF13B Proteins) and IL-17A are associated with different subphenotypes of primary Sjogren's syndrome.
Study demonstrated a correlation between miR (show MLXIP Proteins)-155 and IL-17 in the formation of proteinuria during late onset preeclampsia: positive correlation found between the expression of miR (show MLXIP Proteins)-155 and IL-17 in the serum and placenta, and the number of podocytes in the urine, overexpression of miR (show MLXIP Proteins)-155 caused an increase in IL-17 production, which induced podocyte apoptosis in a dose- and time-dependent manner
High serum IL17 expression is associated with Insulin (show INS Proteins) Resistance.
IL-8 (show IL8 Proteins) polymorphism (rs 2227543) and IL-17 (rs2275913) variants showed significant associations with the severity of acute bronchiolitis.
Potassium supplementation has a blocking effect against salt-loading-induced IL-17A production in T lymphocytes, and the protective effect was mediated through suppression of p38/MAPK (show MAPK14 Proteins)-SGK1 (show SGK1 Proteins) pathway.
Stat3 (show STAT3 Proteins) plays a compensatory anti-apoptotic role in IL-17A/iNOS (show NOS2 Proteins)-mediated cardiomyocyte apoptosis via inhibiting iNOS (show NOS2 Proteins) transcription, providing a novel molecular mechanism of apoptosis regulation and complicated interactions between IL-17A/iNOS (show NOS2 Proteins) and IL-17A/Stat3 (show STAT3 Proteins) signalings.
this study shows that the type of infectious bacteria influences the way in which IL-17A functions during pulmonary infection
Blocking IL-17A alleviates diabetic retinopathy in mice.
IL-17 might be targeted to prevent the progression of airway fibrosis in chronic obstructive pulmonary disease.
IL-17A-mediated expression of epithelial IL-17C (show IL17C Proteins) amplifies the release of chemokines by epithelial cells and thereby contributes to the recruitment of neutrophils and systemic inflammation during acute P. aeruginosa pneumonia.
Taken together, these data show that, in adipose tissues, IL-17A contributes to exacerbating insulin (show INS Proteins) resistance-enhancing IL-6 (show IL6 Proteins) production and promotes the infiltration of Th17 cells in cooperation with TNFalpha (show TNF Proteins); these findings represent a novel hypothesis for the association between IL-17A-producing cells and type 2 diabetes.
Smooth muscle cell-derived IL-17C (show IL17C Proteins) plays a proatherogenic role by supporting the recruitment of Il17a-positive Th17 cells to atherosclerotic lesions.
Lipopolysaccharide treatment significantly suppressed the acute lung injury in mice with Acute lung injury/acute respiratory distress syndrome, accompanied with significant reduction in neutrophil influx, interleukin-17, monocyte chemoattractant protein 1 (show CCL2 Proteins), high-mobility group box 1 (show HMGB1 Proteins) protein, suppressor of cytokine signaling 3 (show SOCS3 Proteins), and surfactant protein D (SP-D (show SFTPD Proteins)) in the lungs .
RORgamma/IL-17A axis influences VEGF (show VEGFA Proteins) production and neovascular retinopathy by mechanisms involving neuroglia. Inhibition of RORgamma and IL-17A may have potential for the improved treatment of neovascular retinopathies.
At week 15, skin cell infiltrates from pigs with crusted scabies had significantly higher CD8 (show CD8A Proteins)+ T cell, gammadelta T cell and IL-17+ cell numbers than those with ordinary scabies. Peripheral IL-17 levels were not increased, suggesting that localized skin IL-17-secreting T cells may play a critical role in the pathogenesis of crusted scabies development.
Alterations in the IL-17 regulated pathway of porcine colon in response to dietary supplementation with seaweeds and yeast are reported.
conclude that only two subpopulations of porcine WBCs are sources of IL-17 after non-specific stimulation: CD3 (show CD3 Proteins)(+)CD4 (show CD4 Proteins)(+) and CD3 (show CD3 Proteins)(+)gammadeltaTCR(+).
Cloning and expression of interleukin-17.
calves, like humans, mount a robust IL-17 response during respiratory syncytial virus infection.
Data show that CD4 (show CD4 Proteins)(+) and WC1(+) gammadelta T-cells were induced to produce IL-17 termed Th17 and gammadelta17 cells.
IL-17A was shown to be upregulated, supporting its investigation as a potential biomarker of bTB.
IL-17A and IL-17F (show IL17F Proteins) have a potential to modulate the mammary gland immune response to mastitis-causing pathogens.
The results of this study provide evidence of the role of IL-17 in the immunopathology of tuberculosis and support the use of IL-17 as a potential biomarker with predictive value of prognosis in bTB.
Data show increased interleukin 17 (IL-17) staining intensity in mediastinal lymph node from chronic recurrent airway obstruction (RAO (show AOC2 Proteins)) horses.
cloning and characterization of interleukin-17 expressed gene sequence from mRNA obtained from intestinal tissue and interleukin-23 expressed gene sequence from mRNA obtained from peripheral blood mononuclear cells
This study examined effects of in vitro exposure to solutions of hay (show GTF2H5 Proteins) dust, lipopolysaccharides, or beta-glucan on cytokine expression in pulmonary mononuclear cells isolated from healthy horses and horses with recurrent airway obstruction.
molecular cloning and expression of recombinant IL-17A; homology modeling revealed that the three-dimensional structure resembles that of human IL-17A. The secondary structure predicted showed the presence of one extra helix in the N-terminal region.
one of the interaction sites between IL17A and its receptor IL17RA (show IL17RA Proteins)
The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.
, Interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8)
, cytotoxic T-lymphocyte-associated antigen 8
, cytotoxic T-lymphocyte-associated protein 8
, interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8)
, interleukin 17