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Mouse (Murine) IL17A Protein expressed in Escherichia coli (E. coli) - ABIN2667468
Ouyang, Kolls, Zheng: The biological functions of T helper 17 cell effector cytokines in inflammation. in Immunity 2008
Show all 10 references for ABIN2667468
Human IL17A Protein expressed in Escherichia coli (E. coli) - ABIN2667466
Yu, Gaffen: Interleukin-17: a novel inflammatory cytokine that bridges innate and adaptive immunity. in Frontiers in bioscience : a journal and virtual library 2007
Show all 7 references for ABIN2667466
Human IL17A Protein expressed in Escherichia coli (E. coli) - ABIN413453
Bérubé, Roussel, Nattagh, Rousseau et al.: Loss of cystic fibrosis transmembrane conductance regulator function enhances activation of p38 and ERK MAPKs, increasing interleukin-6 synthesis in airway epithelial cells exposed to Pseudomonas ... in The Journal of biological chemistry 2010
Show all 3 references for ABIN413453
Rat (Rattus) IL17A Protein expressed in Escherichia coli (E. coli) - ABIN413456
Arif, Moore, Marks, Bouckenooghe, Dayan, Planas, Vives-Pi, Powrie, Tree, Marchetti, Huang, Gurzov, Pujol-Borrell, Eizirik, Peakman: Peripheral and islet interleukin-17 pathway activation characterizes human autoimmune diabetes and promotes cytokine-mediated β-cell death. in Diabetes 2011
Mouse (Murine) IL17A Protein expressed in Escherichia coli (E. coli) - ABIN1033169
Hurst, Muchamuel, Gorman, Gilbert, Clifford, Kwan, Menon, Seymour, Jackson, Kung, Brieland, Zurawski, Chapman, Zurawski, Coffman: New IL-17 family members promote Th1 or Th2 responses in the lung: in vivo function of the novel cytokine IL-25. in Journal of immunology (Baltimore, Md. : 1950) 2002
Data indicate that IL-17/22-producing cells play an important role in maintenance of intestinal mucosa in gluten-sensitive primates.
These results indicate an essential role for MAPKs in the induction of MMP-3 (show MMP3 Proteins) in synovial sarcoma cells, through AP-1 (show FOSB Proteins) activation.
The present study showed that IL-17, in addition to stimulating an inflammatory response, negatively regulates the action of NGF and NGF R in the polar forms of the leprosy.
GG genotype of the rs2275913 IL17A gene promoter polymorphism is associated with significantly impaired long-term kidney allograft function.
we showed that elevated IL-17/IL-23 (show IL23A Proteins) serum concentrations helped to discriminate BP patients who later relapsed.
IL-17 inhibited both the proliferation and migration of periodontal ligament stem cells
IL-17 plays a role in lung cancer progression via different mechanisms. [review]
No associations were found between rs8193036, rs2275913 and rs3748067 in IL-17A and rs763780 in IL-17F (show IL17F Proteins) SNPs and myasthenia gravis in Chinese patients
study found elevations of plasma IL-17A prior to treatment in myasthenia gravis (MG) patients most likely to have thymic hyperplasia and with greater disease severity; also found patients with purely ocular MG more likely to develop generalized weakness with higher IL-17A levels; results further support the role of IL-17A in MG pathogenesis
Data show that the single nucleotide polymorphism of interleukin 17A (IL17A) gene is a risk factor for hepatocellular carcinoma (HCC (show FAM126A Proteins)) development may be through increased serum IL17 and IgE.
IL-17 might also be a culprit in bone destruction caused by late stage bone metastasis[review]
these results suggest that IL-17 intensified IFN-gamma-induced (show SAMHD1 Proteins) NOS2 (show NOS2 Proteins) upregulation and NO production by increasing the transcription activity of p-STAT1 (show STAT1 Proteins)(Y701) and NF-kappaB (show NFKB1 Proteins) in RAW 264.7 cells.
IL17A promotes the formation of lung metastases through tumor-endothelial transmigration.
IL-17 production in the hearts of M2AChR mice is dependent on P2x7 (show P2RX7 Proteins) expression in dilated cardiomyopathy.
Our results show that intestinal inflammation induces the reprogramming of iTreg cells into IL-17-producing cells and that vitamin A restrains reprogramming in the gut (show GUSB Proteins).
impaired induction of acute lung injury in IL-17-deficient mice
A deficiency of IL-17A reduced leukocyte adhesion to endothelium in vivo. IL-17A activated endothelial cells via p38 MAPK (show MAPK14 Proteins) pathway.
Regulatory T-cell Response to Enterotoxigenic Bacteroides fragilis Colonization Triggers IL17-Dependent Colon Carcinogenesis
IL-17A and IL-22 (show IL22 Proteins) work synergistically to induce antimicrobials and chemokines such as IL-8 (show IL8 Proteins), components of calprotectin (show S100A8 Proteins) (CP), lipocalin (show APOD Proteins) (LCN) and some beta-defensins in both human and primary mouse gastric epithelial cells (GEC) and gastroids
gammadelta T cells produce IL-17A, which promotes bone formation and facilitates bone fracture healing. Repair is impaired in IL-17A-deficient mice due to a defect in osteoblastic bone formation.
The study demonstrated the probable involvement of gamma delta T cells in the immune response of an organism via the secretion of IL-17 and IL-22 (show IL22 Proteins).
At week 15, skin cell infiltrates from pigs with crusted scabies had significantly higher CD8 (show CD8A Proteins)+ T cell, gammadelta T cell and IL-17+ cell numbers than those with ordinary scabies. Peripheral IL-17 levels were not increased, suggesting that localized skin IL-17-secreting T cells may play a critical role in the pathogenesis of crusted scabies development.
Alterations in the IL-17 regulated pathway of porcine colon in response to dietary supplementation with seaweeds and yeast are reported.
conclude that only two subpopulations of porcine WBCs are sources of IL-17 after non-specific stimulation: CD3 (show CD3 Proteins)(+)CD4 (show CD4 Proteins)(+) and CD3 (show CD3 Proteins)(+)gammadeltaTCR(+).
Cloning and expression of interleukin-17.
calves, like humans, mount a robust IL-17 response during respiratory syncytial virus infection.
Data show that CD4 (show CD4 Proteins)(+) and WC1(+) gammadelta T-cells were induced to produce IL-17 termed Th17 and gammadelta17 cells.
IL-17A was shown to be upregulated, supporting its investigation as a potential biomarker of bTB.
IL-17A and IL-17F (show IL17F Proteins) have a potential to modulate the mammary gland immune response to mastitis-causing pathogens.
The results of this study provide evidence of the role of IL-17 in the immunopathology of tuberculosis and support the use of IL-17 as a potential biomarker with predictive value of prognosis in bTB.
Data show increased interleukin 17 (IL-17) staining intensity in mediastinal lymph node from chronic recurrent airway obstruction (RAO (show AOC2 Proteins)) horses.
cloning and characterization of interleukin-17 expressed gene sequence from mRNA obtained from intestinal tissue and interleukin-23 expressed gene sequence from mRNA obtained from peripheral blood mononuclear cells
This study examined effects of in vitro exposure to solutions of hay (show GTF2H5 Proteins) dust, lipopolysaccharides, or beta-glucan on cytokine expression in pulmonary mononuclear cells isolated from healthy horses and horses with recurrent airway obstruction.
molecular cloning and expression of recombinant IL-17A; homology modeling revealed that the three-dimensional structure resembles that of human IL-17A. The secondary structure predicted showed the presence of one extra helix in the N-terminal region.
one of the interaction sites between IL17A and its receptor IL17RA (show IL17RA Proteins)
The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.
, Interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8)
, cytotoxic T-lymphocyte-associated antigen 8
, cytotoxic T-lymphocyte-associated protein 8
, interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8)
, interleukin 17