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Browse our IL17A Proteins (IL17A)

Full name:
Interleukin 17A Proteins (IL17A)
On are 127 Interleukin 17A (IL17A) Proteins from 21 different suppliers available. Additionally we are shipping IL17A Antibodies (607) and IL17A Kits (232) and many more products for this protein. A total of 989 IL17A products are currently listed.
ChIL-17, CTLA-8, Ctla8, IL-17, IL-17A, IL-17F, IL17, IL17A
list all proteins Gene Name GeneID UniProt
IL17A 25465  
IL17A 3605 Q16552
IL17A 16171 Q62386

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IL17A Proteins (IL17A) by Origin

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Top referenced IL17A Proteins

  1. Mouse (Murine) IL17A Protein expressed in Escherichia coli (E. coli) - ABIN2667468 : Ouyang, Kolls, Zheng: The biological functions of T helper 17 cell effector cytokines in inflammation. in Immunity 2008 (PubMed)
    Show all 10 references for ABIN2667468

  2. Human IL17A Protein expressed in Escherichia coli (E. coli) - ABIN2667466 : Yu, Gaffen: Interleukin-17: a novel inflammatory cytokine that bridges innate and adaptive immunity. in Frontiers in bioscience : a journal and virtual library 2007 (PubMed)
    Show all 7 references for ABIN2667466

  3. Human IL17A Protein expressed in Escherichia coli (E. coli) - ABIN2667465 : Rouvier, Luciani, Mattéi, Denizot, Golstein: CTLA-8, cloned from an activated T cell, bearing AU-rich messenger RNA instability sequences, and homologous to a herpesvirus saimiri gene. in Journal of immunology (Baltimore, Md. : 1950) 1993 (PubMed)
    Show all 7 references for ABIN2667465

  4. Human IL17A Protein expressed in Escherichia coli (E. coli) - ABIN413453 : Bérubé, Roussel, Nattagh, Rousseau et al.: Loss of cystic fibrosis transmembrane conductance regulator function enhances activation of p38 and ERK MAPKs, increasing interleukin-6 synthesis in airway epithelial cells exposed to Pseudomonas ... in The Journal of biological chemistry 2010 (PubMed)
    Show all 3 references for ABIN413453

  5. Rat (Rattus) IL17A Protein expressed in Escherichia coli (E. coli) - ABIN413456 : Arif, Moore, Marks, Bouckenooghe, Dayan, Planas, Vives-Pi, Powrie, Tree, Marchetti, Huang, Gurzov, Pujol-Borrell, Eizirik, Peakman: Peripheral and islet interleukin-17 pathway activation characterizes human autoimmune diabetes and promotes cytokine-mediated β-cell death. in Diabetes 2011 (PubMed)

More Proteins for IL17A Interaction Partners

Rhesus Monkey Interleukin 17A (IL17A) interaction partners

  1. Data indicate that IL-17/22-producing cells play an important role in maintenance of intestinal mucosa in gluten-sensitive primates.

Human Interleukin 17A (IL17A) interaction partners

  1. The potential pathogenic role of IL-17A-producing T cells in the inflammatory response and fibrosis of Thyroid-associated ophthalmopathy.

  2. These findings suggest that IL-17A is an independent risk factor of non-proliferative diabetic retinopathy, and irisin (show FNDC5 Proteins) could protect against diabetic retinopathy through potential anti-IL-17A effects.

  3. Th17 cells count and the serum IL-17 level were increased in patients with oral squamous cell carcinoma.

  4. Vitreous fluid IL-17A levels were significantly elevated in patients with diabetic retinopathy compared with those of the control group.

  5. PD-1 (show PDCD1 Proteins) is overexpressed in IL-17A-producing T cells in both imiquimod-treated mice and patients with psoriasis. Moreover, recombinant PD-L1 (show CD274 Proteins)-Fc alleviates psoriatic inflammation in imiquimod-treated mice.

  6. BAFF (show TNFSF13B Proteins) and IL-17A are associated with different subphenotypes of primary Sjogren's syndrome.

  7. Study demonstrated a correlation between miR (show MLXIP Proteins)-155 and IL-17 in the formation of proteinuria during late onset preeclampsia: positive correlation found between the expression of miR (show MLXIP Proteins)-155 and IL-17 in the serum and placenta, and the number of podocytes in the urine, overexpression of miR (show MLXIP Proteins)-155 caused an increase in IL-17 production, which induced podocyte apoptosis in a dose- and time-dependent manner

  8. High serum IL17 expression is associated with Insulin (show INS Proteins) Resistance.

  9. IL-8 (show IL8 Proteins) polymorphism (rs 2227543) and IL-17 (rs2275913) variants showed significant associations with the severity of acute bronchiolitis.

  10. Potassium supplementation has a blocking effect against salt-loading-induced IL-17A production in T lymphocytes, and the protective effect was mediated through suppression of p38/MAPK (show MAPK14 Proteins)-SGK1 (show SGK1 Proteins) pathway.

Mouse (Murine) Interleukin 17A (IL17A) interaction partners

  1. Stat3 (show STAT3 Proteins) plays a compensatory anti-apoptotic role in IL-17A/iNOS (show NOS2 Proteins)-mediated cardiomyocyte apoptosis via inhibiting iNOS (show NOS2 Proteins) transcription, providing a novel molecular mechanism of apoptosis regulation and complicated interactions between IL-17A/iNOS (show NOS2 Proteins) and IL-17A/Stat3 (show STAT3 Proteins) signalings.

  2. this study shows that the type of infectious bacteria influences the way in which IL-17A functions during pulmonary infection

  3. Blocking IL-17A alleviates diabetic retinopathy in mice.

  4. IL-17 might be targeted to prevent the progression of airway fibrosis in chronic obstructive pulmonary disease.

  5. PD-1 (show PDCD1 Proteins) is overexpressed in IL-17A-producing T cells in both imiquimod-treated mice and patients with psoriasis. Moreover, recombinant PD-L1 (show CD274 Proteins)-Fc alleviates psoriatic inflammation in imiquimod-treated mice.

  6. IL-17A-mediated expression of epithelial IL-17C (show IL17C Proteins) amplifies the release of chemokines by epithelial cells and thereby contributes to the recruitment of neutrophils and systemic inflammation during acute P. aeruginosa pneumonia.

  7. Taken together, these data show that, in adipose tissues, IL-17A contributes to exacerbating insulin (show INS Proteins) resistance-enhancing IL-6 (show IL6 Proteins) production and promotes the infiltration of Th17 cells in cooperation with TNFalpha (show TNF Proteins); these findings represent a novel hypothesis for the association between IL-17A-producing cells and type 2 diabetes.

  8. Smooth muscle cell-derived IL-17C (show IL17C Proteins) plays a proatherogenic role by supporting the recruitment of Il17a-positive Th17 cells to atherosclerotic lesions.

  9. Lipopolysaccharide treatment significantly suppressed the acute lung injury in mice with Acute lung injury/acute respiratory distress syndrome, accompanied with significant reduction in neutrophil influx, interleukin-17, monocyte chemoattractant protein 1 (show CCL2 Proteins), high-mobility group box 1 (show HMGB1 Proteins) protein, suppressor of cytokine signaling 3 (show SOCS3 Proteins), and surfactant protein D (SP-D (show SFTPD Proteins)) in the lungs .

  10. RORgamma/IL-17A axis influences VEGF (show VEGFA Proteins) production and neovascular retinopathy by mechanisms involving neuroglia. Inhibition of RORgamma and IL-17A may have potential for the improved treatment of neovascular retinopathies.

Pig (Porcine) Interleukin 17A (IL17A) interaction partners

  1. At week 15, skin cell infiltrates from pigs with crusted scabies had significantly higher CD8 (show CD8A Proteins)+ T cell, gammadelta T cell and IL-17+ cell numbers than those with ordinary scabies. Peripheral IL-17 levels were not increased, suggesting that localized skin IL-17-secreting T cells may play a critical role in the pathogenesis of crusted scabies development.

  2. Alterations in the IL-17 regulated pathway of porcine colon in response to dietary supplementation with seaweeds and yeast are reported.

  3. conclude that only two subpopulations of porcine WBCs are sources of IL-17 after non-specific stimulation: CD3 (show CD3 Proteins)(+)CD4 (show CD4 Proteins)(+) and CD3 (show CD3 Proteins)(+)gammadeltaTCR(+).

  4. Cloning and expression of interleukin-17.

Cow (Bovine) Interleukin 17A (IL17A) interaction partners

  1. calves, like humans, mount a robust IL-17 response during respiratory syncytial virus infection.

  2. Data show that CD4 (show CD4 Proteins)(+) and WC1(+) gammadelta T-cells were induced to produce IL-17 termed Th17 and gammadelta17 cells.

  3. IL-17A was shown to be upregulated, supporting its investigation as a potential biomarker of bTB.

  4. IL-17A and IL-17F (show IL17F Proteins) have a potential to modulate the mammary gland immune response to mastitis-causing pathogens.

  5. The results of this study provide evidence of the role of IL-17 in the immunopathology of tuberculosis and support the use of IL-17 as a potential biomarker with predictive value of prognosis in bTB.

Horse (Equine) Interleukin 17A (IL17A) interaction partners

  1. Data show increased interleukin 17 (IL-17) staining intensity in mediastinal lymph node from chronic recurrent airway obstruction (RAO (show AOC2 Proteins)) horses.

  2. cloning and characterization of interleukin-17 expressed gene sequence from mRNA obtained from intestinal tissue and interleukin-23 expressed gene sequence from mRNA obtained from peripheral blood mononuclear cells

  3. This study examined effects of in vitro exposure to solutions of hay (show GTF2H5 Proteins) dust, lipopolysaccharides, or beta-glucan on cytokine expression in pulmonary mononuclear cells isolated from healthy horses and horses with recurrent airway obstruction.

Guinea Pig Interleukin 17A (IL17A) interaction partners

  1. molecular cloning and expression of recombinant IL-17A; homology modeling revealed that the three-dimensional structure resembles that of human IL-17A. The secondary structure predicted showed the presence of one extra helix in the N-terminal region.

Rabbit Interleukin 17A (IL17A) interaction partners

  1. one of the interaction sites between IL17A and its receptor IL17RA (show IL17RA Proteins)

IL17A Protein Profile

Protein Summary

The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.

Alternative names and synonyms associated with IL17A

  • interleukin 17A (Il17a)
  • interleukin 17A (IL17A)
  • interleukin 17A-like (LOC100339322)
  • interleukin 17F (IL17F)
  • ChIL-17 protein
  • CTLA-8 protein
  • Ctla8 protein
  • IL-17 protein
  • IL-17A protein
  • IL-17F protein
  • IL17 protein
  • IL17A protein

Protein level used designations for Interleukin 17A Proteins (IL17A)

interleukin 17A , Interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8) , CTLA-8 , cytotoxic T-lymphocyte-associated antigen 8 , cytotoxic T-lymphocyte-associated protein 8 , interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8) , interleukin-17A , IL-17 , IL-17A , interleukin-17 , interleukin 17

25465 Rattus norvegicus
472029 Pan troglodytes
708123 Macaca mulatta
3605 Homo sapiens
16171 Mus musculus
301289 Rattus norvegicus
449530 Sus scrofa
282863 Bos taurus
100034142 Equus caballus
100735572 Cavia porcellus
100860877 Capra hircus
481837 Canis lupus familiaris
101103931 Ovis aries
100339322 Oryctolagus cuniculus
395111 Gallus gallus
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