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Mouse (Murine) IL17A Protein expressed in Escherichia coli (E. coli) - ABIN2667468
Ouyang, Kolls, Zheng: The biological functions of T helper 17 cell effector cytokines in inflammation. in Immunity 2008
Show all 10 references for ABIN2667468
Human IL17A Protein expressed in Escherichia coli (E. coli) - ABIN2667466
Yu, Gaffen: Interleukin-17: a novel inflammatory cytokine that bridges innate and adaptive immunity. in Frontiers in bioscience : a journal and virtual library 2007
Show all 7 references for ABIN2667466
Human IL17A Protein expressed in Escherichia coli (E. coli) - ABIN2667465
Rouvier, Luciani, Mattéi, Denizot, Golstein: CTLA-8, cloned from an activated T cell, bearing AU-rich messenger RNA instability sequences, and homologous to a herpesvirus saimiri gene. in Journal of immunology (Baltimore, Md. : 1950) 1993
Show all 7 references for ABIN2667465
Human IL17A Protein expressed in Escherichia coli (E. coli) - ABIN413453
Bérubé, Roussel, Nattagh, Rousseau et al.: Loss of cystic fibrosis transmembrane conductance regulator function enhances activation of p38 and ERK MAPKs, increasing interleukin-6 synthesis in airway epithelial cells exposed to Pseudomonas ... in The Journal of biological chemistry 2010
Show all 3 references for ABIN413453
Rat (Rattus) IL17A Protein expressed in Escherichia coli (E. coli) - ABIN413456
Arif, Moore, Marks, Bouckenooghe, Dayan, Planas, Vives-Pi, Powrie, Tree, Marchetti, Huang, Gurzov, Pujol-Borrell, Eizirik, Peakman: Peripheral and islet interleukin-17 pathway activation characterizes human autoimmune diabetes and promotes cytokine-mediated β-cell death. in Diabetes 2011
Data indicate that IL-17/22-producing cells play an important role in maintenance of intestinal mucosa in gluten-sensitive primates.
Because of IL-17 centrality in the pathogenesis of both psoriasis and dry eye disease, this study could provide relevant evidence linking these disorders and, thus, substantiating their epidemiological association
Our findings suggest that, the ratios of Treg/Th17 and IL-10 (show IL10 Proteins)/IL-17 could be used as indicators for the prognosis of CLL, which would be potentially helpful for the disease management and treatment guideline in clinic.
this study shows that IL-17+IFN-gamma (show IFNG Proteins)- and IL-17+IFN-gamma (show IFNG Proteins)+ memory T cell expansion depends on the genotype of the infecting Mycobacterium tuberculosis strains
we analyzed the association of three polymorphism loci (rs2275913, 197 G/A; rs3748067, 383 A/G; and rs763780, 7488 T/C) of IL-17A and IL-17F (show IL17F Proteins) with laryngeal cancer. Allele and genotype frequencies of IL-17A rs2275913 were significantly different between patients and controls with rs2275913 (197 G/A) AA and GA+AA genotypes compared to the GG genotype significantly higher in patients.
Th17 micro-milieu via IL-17A regulates NLRP1-dependent CASP5 (show CASP5 Proteins) activity in psoriatic skin autoinflammation.
High IL-17A expression is associated with polycystic ovary syndrome.
Findings elevated serum IL-17A might be involved in the extravasation of lymphocytes in interstitial pneumonia.
Interleukin-17A (IL-17A) has been shown to be mostly beneficial against infection caused by extracellular bacteria and fungi.
this study shows that miR (show MLXIP Proteins)-23a regulated IL-17-mediated proinflammatory mediators expression in rheumatoid arthritis by directly targeting IKKalpha (show CHUK Proteins)
There were correlations between the levels of IL-6 (show IL6 Proteins), IL-17A.
his study shows that Mir (show MLXIP Proteins)-26a attenuates the development of non-alcoholic fatty liver disease by inhibiting the expression of IL-17 and IL-6 (show IL6 Proteins)
induced IL-17A depletion peritransplant also enhanced acute GVHD, consistent with an additional protective role for this cytokine independent of effects on dysbiosis.
this study shows that madecassoside ointment ameliorates imiquimod-induced skin inflammation and abnormal keratinocyte proliferation by regulating the IL-23 (show IL23A Proteins)/IL-17 axis
Ellagic acid treatment augmented specific IL-10 (show IL10 Proteins) production in response to S. mansoni antigenic stimulation. However, specific IL-1beta (show IL1B Proteins), IL-4 (show IL4 Proteins), IL-12 (show IL12A Proteins), IL-13 (show IL13 Proteins), IL-17A, TNF-alpha (show TNF Proteins) and IFN-gamma (show IFNG Proteins) production were significantly reduced with ex vivo and in vivo ellagic acid treatment.
These results demonstrate that IL-17 is not required for development of severe pathology in response to infection with Borrelia burgdorferi, but may contribute to disease through an interaction with IFN-gamma (show IFNG Proteins).
Results indicate that IL-17A promotes tumorigenicity of colon cancer cells by enhancing cell cycle progression and directly induces the expression of Sca-1.
In conclusion, the data demonstrate that endogenous IL-17 may be a factor determining the severity of CDI in mice.
Choroidal neovascularization lesions trigger a systemic immune response, augmenting local ocular inflammation via the infiltration of IL-17-producing gamma-delta T-cells, which are presumably recruited to the eye in a C5a-dependent manner.
Th17 cells/Il17A participate in the pathogenesis of skin and lung fibrosis by enhancing fibroblast proliferation and cytokine production in a mouse bleomycin model of systemic sclerosis.
These data provide a mechanism where IL-17A affects bone formation by regulating Wnt (show WNT2 Proteins) signaling in osteoblasts and osteocytes.
At week 15, skin cell infiltrates from pigs with crusted scabies had significantly higher CD8 (show CD8A Proteins)+ T cell, gammadelta T cell and IL-17+ cell numbers than those with ordinary scabies. Peripheral IL-17 levels were not increased, suggesting that localized skin IL-17-secreting T cells may play a critical role in the pathogenesis of crusted scabies development.
Alterations in the IL-17 regulated pathway of porcine colon in response to dietary supplementation with seaweeds and yeast are reported.
conclude that only two subpopulations of porcine WBCs are sources of IL-17 after non-specific stimulation: CD3 (show CD3 Proteins)(+)CD4 (show CD4 Proteins)(+) and CD3 (show CD3 Proteins)(+)gammadeltaTCR(+).
Cloning and expression of interleukin-17.
calves, like humans, mount a robust IL-17 response during respiratory syncytial virus infection.
Data show that CD4 (show CD4 Proteins)(+) and WC1(+) gammadelta T-cells were induced to produce IL-17 termed Th17 and gammadelta17 cells.
IL-17A was shown to be upregulated, supporting its investigation as a potential biomarker of bTB.
IL-17A and IL-17F (show IL17F Proteins) have a potential to modulate the mammary gland immune response to mastitis-causing pathogens.
The results of this study provide evidence of the role of IL-17 in the immunopathology of tuberculosis and support the use of IL-17 as a potential biomarker with predictive value of prognosis in bTB.
Data show increased interleukin 17 (IL-17) staining intensity in mediastinal lymph node from chronic recurrent airway obstruction (RAO (show AOC2 Proteins)) horses.
cloning and characterization of interleukin-17 expressed gene sequence from mRNA obtained from intestinal tissue and interleukin-23 expressed gene sequence from mRNA obtained from peripheral blood mononuclear cells
This study examined effects of in vitro exposure to solutions of hay (show GTF2H5 Proteins) dust, lipopolysaccharides, or beta-glucan on cytokine expression in pulmonary mononuclear cells isolated from healthy horses and horses with recurrent airway obstruction.
molecular cloning and expression of recombinant IL-17A; homology modeling revealed that the three-dimensional structure resembles that of human IL-17A. The secondary structure predicted showed the presence of one extra helix in the N-terminal region.
one of the interaction sites between IL17A and its receptor IL17RA (show IL17RA Proteins)
The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.
, Interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8)
, cytotoxic T-lymphocyte-associated antigen 8
, cytotoxic T-lymphocyte-associated protein 8
, interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8)
, interleukin 17